Search Results

Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia

• Authors : Taub, JW; Matherly, LH; Stout, ML

• Source: Blood; April 1996, Vol. 87 Issue: 8 p3395-3403, 9p

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The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia.

• Authors : Su Y; Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan.; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan.

Subjects: Oxidative Phosphorylation* ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism

• Source: Cancer research [Cancer Res] 2024 Apr 01; Vol. 84 (7), pp. 1084-1100.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium:

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Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis in vitro.

• Authors : Hurrish KH; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI, USA.; Su Y

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism ; Isoflavones*/Isoflavones*/Isoflavones*/pharmacology ; Sulfonamides*

• Source: Biochemical pharmacology [Biochem Pharmacol] 2024 Feb; Vol. 220, pp. 115981. Date of Electronic Publication: 2023 Dec 10.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Integrative multi-dimensional characterization of striatal projection neuron heterogeneity in adult brain.

• Authors : Gayden J; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.

• Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 21. Date of Electronic Publication: 2023 Oct 21.Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not

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Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration.

• Authors : Buck SA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA 15213, USA.

• Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 03. Date of Electronic Publication: 2023 Oct 03.Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not

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Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis.

• Authors : Hurrish KH; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI 48201, USA.; Su Y

• Source: Research square [Res Sq] 2023 Apr 28. Date of Electronic Publication: 2023 Apr 28.Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: Res Sq Subsets: PubMed not

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Enhancing crop yields through improvements in the efficiency of photosynthesis and respiration.

• Authors : Garcia A; ARC Centre of Excellence in Plant Energy Biology, Research School of Biology, The Australian National University, Canberra, ACT, 2601, Australia.; Division of Plant Sciences, Research School of Biology, Australian National University, Canberra, ACT, 2601, Australia.

Subjects: Carbon Dioxide*/Carbon Dioxide*/Carbon Dioxide*/metabolism ; Crops, Agricultural*/Crops, Agricultural*/Crops, Agricultural*/physiology ; Cytochrome P-450 CYP2B1*/Cytochrome P-450 CYP2B1*/Cytochrome P-450 CYP2B1*/metabolism

• Source: The New phytologist [New Phytol] 2023 Jan; Vol. 237 (1), pp. 60-77. Date of Electronic Publication: 2022 Nov 17.Publisher: Wiley on behalf of New Phytologist Trust Country of Publication: England NLM ID: 9882884 Publication Model: Print-Electronic Cited Medium:

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Sex Differences in Dopaminergic Vulnerability to Environmental Toxicants - Implications for Parkinson's Disease.

• Authors : Adamson A; Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, 1719 6th Ave South, CIRC 560, Birmingham, AL, 35294, USA.; Buck SA

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/etiology; Female ; Male

• Source: Current environmental health reports [Curr Environ Health Rep] 2022 Dec; Vol. 9 (4), pp. 563-573. Date of Electronic Publication: 2022 Oct 06.Publisher: Springer International Publishing AG Country of Publication: Switzerland NLM ID: 101629387 Publication Model: Print-Electronic Cited Medium:

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Relevance of interactions between dopamine and glutamate neurotransmission in schizophrenia.

• Authors : Buck SA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15213, USA.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, USA.

Subjects: Dopamine*/Dopamine*/Dopamine*/physiology ; Schizophrenia*; Humans

• Source: Molecular psychiatry [Mol Psychiatry] 2022 Sep; Vol. 27 (9), pp. 3583-3591. Date of Electronic Publication: 2022 Jun 10.Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium:

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Roles of VGLUT2 and Dopamine/Glutamate Co-Transmission in Selective Vulnerability to Dopamine Neurodegeneration.

• Authors : Buck SA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, United States.

Subjects: Dopamine* ; Parkinson Disease*; Dopaminergic Neurons

• Source: ACS chemical neuroscience [ACS Chem Neurosci] 2022 Jan 19; Vol. 13 (2), pp. 187-193. Date of Electronic Publication: 2022 Jan 07.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet

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VGLUT2 Is a Determinant of Dopamine Neuron Resilience in a Rotenone Model of Dopamine Neurodegeneration.

• Authors : Buck SA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213.

Subjects: Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*pathology ; Nerve Degeneration/Nerve Degeneration/Nerve Degeneration/*pathology ; Parkinsonian Disorders/Parkinsonian Disorders/Parkinsonian Disorders/*metabolism

• Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Jun 02; Vol. 41 (22), pp. 4937-4947. Date of Electronic Publication: 2021 Apr Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet

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Vesicular glutamate transporter modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration.

• Authors : Buck SA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.

Subjects: Sex Characteristics*; Aging/Aging/Aging/*physiology ; Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*physiology

• Source: Aging cell [Aging Cell] 2021 May; Vol. 20 (5), pp. e13365. Date of Electronic Publication: 2021 Apr 28.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Roles of dopamine and glutamate co-release in the nucleus accumbens in mediating the actions of drugs of abuse.

• Authors : Buck SA; Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Psychiatry, Translational Neuroscience Program, University of Pittsburgh, Pittsburgh, PA, USA.

Subjects: Analgesics, Opioid/Analgesics, Opioid/Analgesics, Opioid/*adverse effects ; Cocaine/Cocaine/Cocaine/*adverse effects ; Dopamine/Dopamine/Dopamine/*metabolism

• Source: The FEBS journal [FEBS J] 2021 Mar; Vol. 288 (5), pp. 1462-1474. Date of Electronic Publication: 2020 Aug 11.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Exposure to elevated embryonic kynurenine in rats: Sex-dependent learning and memory impairments in adult offspring.

• Authors : Buck SA; Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.; Baratta AM

Subjects: Sex Characteristics*; Brain/Brain/Brain/*drug effects ; Kynurenine/Kynurenine/Kynurenine/*administration & dosage

• Source: Neurobiology of learning and memory [Neurobiol Learn Mem] 2020 Oct; Vol. 174, pp. 107282. Date of Electronic Publication: 2020 Jul 30.Publisher: Academic Press Country of Publication: United States NLM ID: 9508166 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia.

• Authors : Luedtke DA; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, MI, 48201, USA.; Su Y

Subjects: Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*administration & dosage ; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*genetics ; Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/*drug therapy

• Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2020 Feb 26; Vol. 5 (1), pp. 17. Date of Electronic Publication: 2020 Feb 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN:

Record details

Sex Differences in Hippocampal Memory and Kynurenic Acid Formation Following Acute Sleep Deprivation in Rats.

• Authors : Baratta AM; Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Buck SA

Subjects: Hippocampus/Hippocampus/Hippocampus/*metabolism ; Kynurenic Acid/Kynurenic Acid/Kynurenic Acid/*metabolism ; Sleep Deprivation/Sleep Deprivation/Sleep Deprivation/*metabolism

• Source: Scientific reports [Sci Rep] 2018 May 03; Vol. 8 (1), pp. 6963. Date of Electronic Publication: 2018 May 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Evidence for Increased Response to Induced Endoplasmic Reticulum Stress in Myeloid Cells in Acquired Aplastic Anemia.

• Authors : Sidhu A; Department of Pediatrics and Human Development, Michigan State University, East Lansing, MI †Department of Pediatrics, Wayne State University School of Medicine, Children's Hospital of Michigan ‡Molecular Therapeutics Program, Karmanos Cancer Institute §Pediatric Blood and Marrow Transplant Program, Children's Hospital of Michigan, Barbara Ann Karmanos Cancer Center, Detroit, MI.; Callaghan MU

Subjects: Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/physiology ; Unfolded Protein Response*; Anemia, Aplastic/Anemia, Aplastic/Anemia, Aplastic/*etiology

• Source: Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2017 Apr; Vol. 39 (3), pp. e163-e166.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505928 Publication Model: Print Cited Medium: Internet ISSN:

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Spontaneous remission of congenital AML with skin involvement and t(1;11)(p32;q23).

• Authors : Jesudas R; Division of Hematology/Oncology, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan.; Buck SA

Subjects: Neoplasm Regression, Spontaneous*; Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/*pathology ; Skin Neoplasms/Skin Neoplasms/Skin Neoplasms/*pathology

• Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2017 Mar; Vol. 64 (3). Date of Electronic Publication: 2016 Sep 29.Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Comparative genomics and prediction of conditionally dispensable sequences in legume-infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors.

• Authors : Williams AH; The Institute of Agriculture, The University of Western Australia, 35 Stirling Highway, Crawley, WA, 6009, Australia. .; CSIRO Agriculture, Centre for Environment and Life Sciences, Wembley, WA, 6913, Australia. .

Subjects: Genome, Fungal*; Fabaceae/Fabaceae/Fabaceae/*microbiology ; Fusarium/Fusarium/Fusarium/*genetics

• Source: BMC genomics [BMC Genomics] 2016 Mar 05; Vol. 17, pp. 191. Date of Electronic Publication: 2016 Mar 05.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Targeting histone deacetylases (HDACs) and Wee1 for treating high-risk neuroblastoma.

• Authors : Hanmod SS; Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, Michigan.; Wang G

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*antagonists & inhibitors ; Histone Deacetylases/Histone Deacetylases/Histone Deacetylases/*chemistry

• Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2015 Jan; Vol. 62 (1), pp. 52-9. Date of Electronic Publication: 2014 Oct 12.Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Targeting the wee1 kinase for treatment of pediatric Down syndrome acute myeloid leukemia.

• Authors : Caldwell JT; MD/PhD Program, Wayne State University School of Medicine, Detroit, Michigan; Cancer Biology Graduate Program, Wayne State University School of Medicine, Detroit, Michigan.

Subjects: Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*pharmacology ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*antagonists & inhibitors ; Down Syndrome/Down Syndrome/Down Syndrome/*complications

• Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2014 Oct; Vol. 61 (10), pp. 1767-73. Date of Electronic Publication: 2014 Jun 24.Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Panobinostat enhances cytarabine and daunorubicin sensitivities in AML cells through suppressing the expression of BRCA1, CHK1, and Rad51.

• Authors : Xie C; Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan, United States of America ; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America

Subjects: Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/*pharmacology ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology ; BRCA1 Protein/BRCA1 Protein/BRCA1 Protein/*biosynthesis

• Source: PloS one [PLoS One] 2013 Nov 11; Vol. 8 (11), pp. e79106. Date of Electronic Publication: 2013 Nov 11 (Print Publication: 2013).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Panobinostat synergistically enhances the cytotoxic effects of cisplatin, doxorubicin or etoposide on high-risk neuroblastoma cells.

• Authors : Wang G; Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, United States of America ; College of Life Science, Jilin University, Changchun, China.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/*pharmacology

• Source: PloS one [PLoS One] 2013 Sep 30; Vol. 8 (9), pp. e76662. Date of Electronic Publication: 2013 Sep 30 (Print Publication: 2013).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

Record details

Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia.

• Authors : Caldwell JT; Wayne State University School of Medicine, Detroit, Michigan, United States of America.; Edwards H

Subjects: Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics ; GATA1 Transcription Factor/GATA1 Transcription Factor/GATA1 Transcription Factor/*genetics ; Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/*genetics

• Source: PloS one [PLoS One] 2013 Jul 10; Vol. 8 (7), pp. e68601. Date of Electronic Publication: 2013 Jul 10 (Print Publication: 2013).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet

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Valproic acid synergistically enhances the cytotoxicity of clofarabine in pediatric acute myeloid leukemia cells.

• Authors : Xie C; Department of Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA.; Edwards H

Subjects: Drug Screening Assays, Antitumor*; Adenine Nucleotides/Adenine Nucleotides/Adenine Nucleotides/*administration & dosage ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage

• Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2012 Dec 15; Vol. 59 (7), pp. 1245-51. Date of Electronic Publication: 2012 Apr 05.Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line.

• Authors : Vangipuram SD; Children's Research Center of Michigan, The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, USA. ; Buck SA

Subjects: Drug Resistance, Neoplasm*; Doxorubicin/Doxorubicin/Doxorubicin/*pharmacology ; Neoplastic Stem Cells/Neoplastic Stem Cells/Neoplastic Stem Cells/*drug effects

• Source: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine [Tumour Biol] 2012 Dec; Vol. 33 (6), pp. 2173-83. Date of Electronic Publication: Publisher: IOS Press Country of Publication: Netherlands NLM ID: 8409922 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells.

• Authors : Xu X; Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America.; Xie C

Subjects: Histone Deacetylases*/Histone Deacetylases*/Histone Deacetylases*/metabolism; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*therapeutic use ; Apoptosis/Apoptosis/Apoptosis/*drug effects

• Source: PloS one [PLoS One] 2011 Feb 16; Vol. 6 (2), pp. e17138. Date of Electronic Publication: 2011 Feb 16.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet

Record details

A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.

• Authors : Xavier AC; Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, Michigan, United States of America.; Edwards H

Subjects: Down Syndrome/Down Syndrome/Down Syndrome/*complications ; GATA1 Transcription Factor/GATA1 Transcription Factor/GATA1 Transcription Factor/*metabolism ; Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/*drug therapy

• Source: PloS one [PLoS One] 2011; Vol. 6 (11), pp. e27486. Date of Electronic Publication: 2011 Nov 16.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric acute myeloid leukemia.

• Authors : Xie C; Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, 110 E. Warren Avenue, Detroit, MI 48201, USA.; Edwards H

Subjects: Cytarabine/Cytarabine/Cytarabine/*pharmacology ; Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/*drug therapy ; Valproic Acid/Valproic Acid/Valproic Acid/*pharmacology

• Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2010 Nov 15; Vol. 16 (22), pp. 5499-510. Date of Electronic Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia.

• Authors : Edwards H; Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA.; Xie C

Subjects: Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/*physiology ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics ; Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/*genetics

• Source: Blood [Blood] 2009 Sep 24; Vol. 114 (13), pp. 2744-52. Date of Electronic Publication: 2009 Jul 28.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Synthesis and discovery of high affinity folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.

• Authors : Deng Y; Graduate Program in Cancer Biology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.; Wang Y

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*chemical synthesis ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*chemical synthesis ; Folic Acid Antagonists/Folic Acid Antagonists/Folic Acid Antagonists/*chemical synthesis

• Source: Journal of medicinal chemistry [J Med Chem] 2008 Aug 28; Vol. 51 (16), pp. 5052-63. Date of Electronic Publication: 2008 Aug 05.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy.

• Authors : Ge Y; Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.; LaFiura KM

Subjects: Gene Expression Regulation, Leukemic/Gene Expression Regulation, Leukemic/Gene Expression Regulation, Leukemic/*physiology ; Leukemia, Myeloid/Leukemia, Myeloid/Leukemia, Myeloid/*etiology ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*physiology

• Source: Leukemia [Leukemia] 2008 Mar; Vol. 22 (3), pp. 521-9. Date of Electronic Publication: 2007 Dec 20.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia.

• Authors : Ge Y; Experimental and Clinical Therapeutics Program, Barbara Ann Karmanos Cancer Institute of Environmental Sciences, Wayne State University, Detroit, MI 48201, USA.; Dombkowski AA

Subjects: Down Syndrome/Down Syndrome/Down Syndrome/*genetics ; GATA1 Transcription Factor/GATA1 Transcription Factor/GATA1 Transcription Factor/*genetics ; Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/*drug therapy

• Source: Blood [Blood] 2006 Feb 15; Vol. 107 (4), pp. 1570-81. Date of Electronic Publication: 2005 Oct 25.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0006-4971

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Role of USF1 in the differential expression of the human deoxycytidine kinase gene in acute myeloid leukemia.

• Authors : Ge Y; Jensen TL; Tatman DA

Subjects: DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics ; Deoxycytidine Kinase/Deoxycytidine Kinase/Deoxycytidine Kinase/*genetics ; Leukemia, Myeloid/Leukemia, Myeloid/Leukemia, Myeloid/*genetics

• Source: Leukemia [Leukemia] 2005 Apr; Vol. 19 (4), pp. 677-9.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print Cited Medium: Print

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Metabolic alterations in genetically selected Drosophila strains with different longevities.

• Authors : Buck SA; Department of Biological Sciences, Wayne State University, Detroit, MI 48202 USA.; Arking R

• Source: Journal of the American Aging Association [J Am Aging Assoc] 2001 Oct; Vol. 24 (4), pp. 151-61.Publisher: American Aging Association Country of Publication: United States NLM ID: 100964172 Publication Model: Print Cited Medium: Print ISSN:

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Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin.

• Authors : Taub JW; Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI, USA.; Huang X

Subjects: Chromosomes, Human, Pair 21*; Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/*pharmacology ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology

• Source: Blood [Blood] 1999 Aug 15; Vol. 94 (4), pp. 1393-400.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Print ISSN: 0006-4971 (Print)

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Myeloblasts from Down syndrome children with acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin.

• Authors : Taub JW; Stout ML; Buck SA

Subjects: Cytarabine/Cytarabine/Cytarabine/*therapeutic use ; Daunorubicin/Daunorubicin/Daunorubicin/*therapeutic use ; Down Syndrome/Down Syndrome/Down Syndrome/*pathology

• Source: Leukemia [Leukemia] 1997 Sep; Vol. 11 (9), pp. 1594-5.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print Cited Medium: Print

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The differentiation of delayed serologic and delayed hemolytic transfusion reactions: incidence, long-term serologic findings, and clinical significance.

• Authors : Ness PM; Johns Hopkins Hospital Blood Bank, Baltimore, Maryland.; Shirey RS

Subjects: Antigen-Antibody Complex* ; Hemolysis* ; Transfusion Reaction*

• Source: Transfusion [Transfusion] 1990 Oct; Vol. 30 (8), pp. 688-93.Publisher: American Association Of Blood Banks Country of Publication: United States NLM ID: 0417360 Publication Model: Print Cited Medium: Print

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The utility of platelet washing using an automated procedure for severe platelet allergic reactions.

• Authors : Buck SA; Kickler TS; McGuire M

Subjects: Blood Platelets*/Blood Platelets*/Blood Platelets*/immunology ; Blood Platelets*/Blood Platelets*/Blood Platelets*/physiology; Hypersensitivity/Hypersensitivity/Hypersensitivity/*prevention & control

• Source: Transfusion [Transfusion] 1987 Sep-Oct; Vol. 27 (5), pp. 391-3.Publisher: American Association Of Blood Banks Country of Publication: United States NLM ID: 0417360 Publication Model: Print Cited Medium: Print

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SELECTION FOR DELAYED SENESCENCE IN DROSOPHILA MELANOGASTER.

• Authors : Luckinbill LS; Department of Biological Sciences, Wayne State University, Detroit, Michigan, 48202.; Arking R

• Source: Evolution; international journal of organic evolution [Evolution] 1984 Sep; Vol. 38 (5), pp. 996-1003.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0373224 Publication Model: Print Cited Medium: Internet ISSN:

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