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  • 1-10 of  4,263 results for ""Cytochrome P-450 CYP2C19""

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Academic Journal

The effects of CYP2C19 genotype polymorphism and clopidogrel resistance on ischemic event occurrence in patients with peripheral arterial disease undergoing revascularization: A prospective cohort study.

  • Authors : Zhang Y; Diagnosis and Treatment Center of Vascular Disease, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.; Ran Q

Subjects: Clopidogrel*/Clopidogrel*/Clopidogrel*/therapeutic use ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/metabolism

  • Source: Thrombosis research [Thromb Res] 2024 Apr; Vol. 236, pp. 37-50. Date of Electronic Publication: 2024 Feb 17.Publisher: Pergamon Press Country of Publication: United States NLM ID: 0326377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Impact of CYP2C:TG Haplotype on CYP2C19 Substrates Clearance In Vivo, Protein Content, and In Vitro Activity.

  • Authors : Zubiaur P; Clinical Pharmacology Department, Hospital Universitario de La Princesa, Instituto Teófilo Hernando, Universidad Autónoma de Madrid (UAM), Instituto de Investigación Sanitaria La Princesa (IP), Madrid, Spain.; Division of Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Research Institute (CMRI), Kansas City, Missouri, USA.

Subjects: Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism; Humans

  • Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2023 Nov; Vol. 114 (5), pp. 1033-1042. Date of Electronic Publication: 2023 Aug 11.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535

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Academic Journal

CYP2C19 loss-of-function alleles are not associated with higher prevalence of gastrointestinal bleeds in those who have been prescribed antidepressants: Analysis in a British-South Asian cohort.

Subjects: Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/adverse effects ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/metabolism ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Nov; Vol. 89 (11), pp. 3432-3438. Date of Electronic Publication: 2023 Aug 06.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

CYP2C19*17 association with higher plasma 4-hydroxy tamoxifen in Pakistani (estrogen-positive) breast cancer patients.

  • Authors : Tareen MU; Department of Biochemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan.; Riaz S

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology

  • Source: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2023 Sep; Vol. 248 (17), pp. 1507-1517. Date of Electronic Publication: 2023 Sep 09.Publisher: Sage Country of Publication: Switzerland NLM ID: 100973463 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3699

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Academic Journal

Association of CYP2C19 Loss-of-Function Metabolizer Status With Stroke Risk Among Chinese Patients Treated With Ticagrelor-Aspirin vs Clopidogrel-Aspirin: A Prespecified Secondary Analysis of a Randomized Clinical Trial.

  • Authors : Xie X; China National Clinical Research Center for Neurological Diseases, Beijing, China.; Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Subjects: Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Ischemic Attack, Transient*/Ischemic Attack, Transient*/Ischemic Attack, Transient*/drug therapy ; Ischemic Stroke*/Ischemic Stroke*/Ischemic Stroke*/drug therapy

  • Source: JAMA network open [JAMA Netw Open] 2023 Jun 01; Vol. 6 (6), pp. e2317037. Date of Electronic Publication: 2023 Jun 01.Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Feasibility of Community Pharmacist-Initiated and Point-of-Care CYP2C19 Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors.

  • Authors : Levens AD; Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.; den Haan MC

Subjects: Acute Coronary Syndrome*/Acute Coronary Syndrome*/Acute Coronary Syndrome*/drug therapy ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/Platelet Aggregation Inhibitors*/therapeutic use

  • Source: Genes [Genes (Basel)] 2023 Feb 25; Vol. 14 (3). Date of Electronic Publication: 2023 Feb 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425

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Academic Journal

The Frequency of CYP2C19 Loss-of-Function Variants in Patients with Non-Cardioembolic Ischemic Stroke or Transient Ischemic Attack in the Dutch Population.

Subjects: Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Gene Frequency* ; Ischemic Attack, Transient*/Ischemic Attack, Transient*/Ischemic Attack, Transient*/drug therapy

  • Source: Cerebrovascular diseases (Basel, Switzerland) [Cerebrovasc Dis] 2023; Vol. 52 (6), pp. 700-705. Date of Electronic Publication: 2023 Mar 22.Publisher: Karger Country of Publication: Switzerland NLM ID: 9100851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9786

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Academic Journal

Generation of cytochrome P450 enzyme-polymorphic human induced pluripotent stem cell lines with CYP2D6*10/CYP3A5*3C and CYP2D6*10/CYP2C19*2.

  • Authors : Lee J; Laboratory of Stem Cells and Tissue Regeneration, Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, South Korea; Department of New Drug Development, NEXEL Co., Ltd., Seoul 02580, South Korea.

Subjects: Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics

  • Source: Stem cell research [Stem Cell Res] 2022 Dec; Vol. 65, pp. 102970. Date of Electronic Publication: 2022 Nov 14.Publisher: Elsevier Country of Publication: England NLM ID: 101316957 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-7753

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Academic Journal

Genetic polymorphism of clopidogrel metabolism related gene CYP2C19 gene in Chinese from Foshan area of Guangdong Province.

  • Authors : Yuan XW; Department of The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, People's Republic of China.; Yuan SY

Subjects: Clopidogrel*/Clopidogrel*/Clopidogrel*/pharmacology ; Clopidogrel*/Clopidogrel*/Clopidogrel*/therapeutic use ; Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/Cytochrome P-450 CYP2C19*/genetics

  • Source: Hematology (Amsterdam, Netherlands) [Hematology] 2022 Dec; Vol. 27 (1), pp. 1056-1061.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print Cited Medium: Internet ISSN: 1607-8454

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  • 1-10 of  4,263 results for ""Cytochrome P-450 CYP2C19""