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Academic Journal

Increases in computationally predicted deleterious variants of unknown significance and sperm mtDNA copy numbers may be associated with semen quality.

  • Authors : Pi Y; Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, Hunan, China.; Huang Z

Subjects: Semen Analysis* ; DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/genetics ; DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/metabolism

  • Source: Andrology [Andrology] 2024 Mar; Vol. 12 (3), pp. 585-598. Date of Electronic Publication: 2023 Aug 25.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101585129 Publication Model: Print-Electronic Cited

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Academic Journal

Nucleic acid vaccines-based therapy for triple-negative breast cancer: A new paradigm in tumor immunotherapy arena.

  • Authors : Saleh RO; Department of Medical Laboratory Techniques, Al-Maarif University College, Al-Anbar, Iraq.; Ibrahim FM

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Vaccines, DNA*

  • Source: Cell biochemistry and function [Cell Biochem Funct] 2024 Apr; Vol. 42 (3), pp. e3992.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8305874 Publication Model: Print Cited Medium:

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Academic Journal

Low-pass whole genome sequencing is a reliable and cost-effective approach for copy number variant analysis in the clinical setting.

  • Authors : Mazzonetto PC; The Human Genome and Stem Cell Research Center, Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, SP, Brazil.; Diagnósticos da América S.A., DASA, São Paulo, Brazil.

Subjects: DNA Copy Number Variations* ; Aneuploidy*; Pregnancy

  • Source: Annals of human genetics [Ann Hum Genet] 2024 Mar; Vol. 88 (2), pp. 113-125. Date of Electronic Publication: 2023 Oct 09.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0416661 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The relationship between sperm nuclear DNA fragmentation, mitochondrial DNA fragmentation, and copy number in normal and abnormal human ejaculates.

  • Authors : Tímermans A; INIBIC-Complexo Hospitalario Universitario A Coruña (CHUAC), Spain.; Laboratory of Molecular Genetics and Radiobiology, Centro Oncológico de Galicia, Doctor Camilo Veiras, Spain.

Subjects: DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/genetics ; DNA Copy Number Variations*; Humans

  • Source: Andrology [Andrology] 2024 May; Vol. 12 (4), pp. 870-880. Date of Electronic Publication: 2023 Oct 02.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101585129 Publication Model: Print-Electronic Cited

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Academic Journal

Copy number variants and fetal structural abnormalities in stillborn fetuses: A secondary analysis of the Stillbirth Collaborative Research Network study.

Subjects: Stillbirth*/Stillbirth*/Stillbirth*/epidemiology ; Stillbirth*/Stillbirth*/Stillbirth*/genetics ; DNA Copy Number Variations*/DNA Copy Number Variations*/DNA Copy Number Variations*/genetics

  • Source: BJOG : an international journal of obstetrics and gynaecology [BJOG] 2024 Jan; Vol. 131 (2), pp. 157-162. Date of Electronic Publication: 2023 Jun 01.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100935741 Publication Model: Print-Electronic Cited

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Academic Journal

A phenotypic screen with Trypanosoma brucei for discovering small molecules that target the SLiM-binding pocket of proliferating cell nuclear antigen orthologs.

  • Authors : Actis M; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Fujii N

Subjects: DNA Replication* ; Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/Trypanosoma brucei brucei*/metabolism; Humans

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2024 Jan; Vol. 103 (1), pp. e14361. Date of Electronic Publication: 2023 Sep 28.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited

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Academic Journal

Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.

  • Authors : Zhang L; Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Subjects: DNA Damage* ; Lymphoma, B-Cell*/Lymphoma, B-Cell*/Lymphoma, B-Cell*/genetics; Humans

  • Source: EMBO molecular medicine [EMBO Mol Med] 2023 Sep 11; Vol. 15 (9), pp. e16431. Date of Electronic Publication: 2023 Jul 24.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101487380 Publication Model: Print-Electronic Cited

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Academic Journal

Region-based epigenetic clock design improves RRBS-based age prediction.

  • Authors : Simpson DJ; MRC Human Genetics Unit, MRC Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Zhao Q

Subjects: DNA Methylation*/DNA Methylation*/DNA Methylation*/genetics ; Epigenomics*; Mice

  • Source: Aging cell [Aging Cell] 2023 Aug; Vol. 22 (8), pp. e13866. Date of Electronic Publication: 2023 May 11.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited

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Academic Journal

Transgenerational impact of grand-paternal lifetime exposures to both folic acid deficiency and supplementation on genome-wide DNA methylation in male germ cells.

  • Authors : Chan D; Research Institute of the McGill University Health Centre, Montreal, QC, Canada.; Ly L

Subjects: DNA Methylation* ; Folic Acid Deficiency*/Folic Acid Deficiency*/Folic Acid Deficiency*/genetics ; Folic Acid Deficiency*/Folic Acid Deficiency*/Folic Acid Deficiency*/metabolism

  • Source: Andrology [Andrology] 2023 Jul; Vol. 11 (5), pp. 927-942. Date of Electronic Publication: 2023 Feb 17.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101585129 Publication Model: Print-Electronic Cited

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Academic Journal

A decrease in NR2B expression mediated by DNA hypermethylation induces perioperative neurocognitive disorder in aged mice.

  • Authors : Xu F; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.; Cong P

Subjects: Cognition Disorders*/Cognition Disorders*/Cognition Disorders*/metabolism ; DNA Methylation* ; Receptors, N-Methyl-D-Aspartate*/Receptors, N-Methyl-D-Aspartate*/Receptors, N-Methyl-D-Aspartate*/genetics

  • Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2023 May; Vol. 29 (5), pp. 1229-1242. Date of Electronic Publication: 2023 Jan 24.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print-Electronic Cited

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