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Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease.

• Authors : De Miranda BR; Center for Environmental Medicine, Department of Environmental and Radiological Health Sciences, Animal Cancer Center, Colorado State University, Fort Collins, Colorado 80523-1680, USA.; Miller JA

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*therapeutic use ; Indoles/Indoles/Indoles/*pharmacokinetics

• Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2013 Apr; Vol. 345 (1), pp. 125-38. Date of Electronic Publication: 2013 Jan 14.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model:

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Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease.

• Authors : De Miranda BR; Department of Environmental and Radiological Health Sciences, Center for Environmental Medicine, Colorado State University, Fort Collins, Colorado 80523-1680, Texas A&M Health Science Center, Houston, TX 77030, Texas and Department of Veterinary Physiology and Pharmacology, Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University, College Station, TX 77843, Texas.; Popichak KA

Subjects: Anisoles/Anisoles/Anisoles/*pharmacology ; Antiparkinson Agents/Antiparkinson Agents/Antiparkinson Agents/*pharmacology ; Indoles/Indoles/Indoles/*pharmacology

• Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2015 Feb; Vol. 143 (2), pp. 360-73. Date of Electronic Publication: 2014 Nov 17.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Internet

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The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expression in BV-2 Microglial Cells by Inhibiting Nuclear Factor κB.

• Authors : De Miranda BR; Center for Environmental Medicine, Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, Colorado (B.R.D.M., K.A.P., S.L.H., B.A.J., A.T.P., R.B.T.); Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, Texas

Subjects: Indoles/Indoles/Indoles/*pharmacology ; Microglia/Microglia/Microglia/*drug effects ; Nuclear Receptor Subfamily 4, Group A, Member 2/Nuclear Receptor Subfamily 4, Group A, Member 2/Nuclear Receptor Subfamily 4, Group A, Member 2/*metabolism

• Source: Molecular pharmacology [Mol Pharmacol] 2015 Jun; Vol. 87 (6), pp. 1021-34. Date of Electronic Publication: 2015 Apr 09.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model:

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Astrocyte-specific DJ-1 overexpression protects against rotenone-induced neurotoxicity in a rat model of Parkinson's disease.

• Authors : De Miranda BR; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, United States; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, United States.

Subjects: Astrocytes/Astrocytes/Astrocytes/*metabolism ; Insecticides/Insecticides/Insecticides/*toxicity ; Parkinsonian Disorders/Parkinsonian Disorders/Parkinsonian Disorders/*metabolism

• Source: Neurobiology of disease [Neurobiol Dis] 2018 Jul; Vol. 115, pp. 101-114. Date of Electronic Publication: 2018 Apr 09.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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LRRK2 activation in idiopathic Parkinson's disease.

• Authors : Di Maio R; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Subjects: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/*metabolism ; Parkinson Disease/Parkinson Disease/Parkinson Disease/*metabolism; 14-3-3 Proteins/14-3-3 Proteins/14-3-3 Proteins/genetics

• Source: Science translational medicine [Sci Transl Med] 2018 Jul 25; Vol. 10 (451).Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited

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Long-term RNAi knockdown of α-synuclein in the adult rat substantia nigra without neurodegeneration.

• Authors : Zharikov A; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA, USA.

Subjects: Nerve Degeneration/Nerve Degeneration/Nerve Degeneration/*etiology ; RNAi Therapeutics/RNAi Therapeutics/RNAi Therapeutics/*methods ; Substantia Nigra/Substantia Nigra/Substantia Nigra/*pathology

• Source: Neurobiology of disease [Neurobiol Dis] 2019 May; Vol. 125, pp. 146-153. Date of Electronic Publication: 2019 Jan 15.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Response to Rotenone and Parkinson's Disease; Reduced Sensitivity in Females.

• Authors : De Miranda BR; Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.; Greenamyre JT

Subjects: Insecticides* ; Parkinson Disease*; Female

• Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2019 Jun 01; Vol. 170 (2), pp. 563.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN:

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Sex Differences in Rotenone Sensitivity Reflect the Male-to-Female Ratio in Human Parkinson's Disease Incidence.

• Authors : De Miranda BR; Pittsburgh Institute for Neurodegenerative Diseases.; Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213.

Subjects: Parkinson Disease/Parkinson Disease/Parkinson Disease/*metabolism ; Rotenone/Rotenone/Rotenone/*toxicity; Animals

• Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2019 Jul 01; Vol. 170 (1), pp. 133-143.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN:

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LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease.

• Authors : Rocha EM; Pittsburgh Institute for Neurodegenerative Diseases, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, United States of America. Electronic address: .; De Miranda BR

Subjects: Parkinson Disease*; Dopaminergic Neurons/Dopaminergic Neurons/Dopaminergic Neurons/*pathology ; Endosomes/Endosomes/Endosomes/*pathology

• Source: Neurobiology of disease [Neurobiol Dis] 2020 Feb; Vol. 134, pp. 104626. Date of Electronic Publication: 2019 Oct 13.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Minimally invasive tenodesis for peroneus longus tendon rupture: A case report and review of literature.

• Authors : Nishikawa DRC; Department of Orthopedics, Foot and Ankle Surgery, Hospital of the Municipal Public Servant of São Paulo (HSPM), Aclimação 01532-000, São Paulo, Brazil. .; Duarte FA

• Source: World journal of orthopedics [World J Orthop] 2020 Feb 18; Vol. 11 (2), pp. 137-144. Date of Electronic Publication: 2020 Feb 18 (Print Publication: 2020).Publisher: Baishideng Publishing Group Country of Publication: United States NLM ID: 101576349 Publication Model: eCollection Cited Medium: Print

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