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Academic Journal

Daily Statin Trial for People With HIV Halted Early for Clear Benefit.

Subjects: Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/etiology ; Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/prevention & control ; HIV Infections*/HIV Infections*/HIV Infections*/complications

  • Source: JAMA [JAMA] 2023 May 16; Vol. 329 (19), pp. 1633.Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN:

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Editorial & Opinion

Early stopping of a randomised trial for efficacy: a medical, ethical and regulatory challenge.

  • Authors : Darmon A; FACT (French Alliance for Cardiovascular Trials), DHU-FIRE, Hopital Bichat-Claude Bernard, Paris, France .; Université de Paris, Assistance Publique-Hôpitaux de Paris, Paris, France.

Subjects: Continuity of Patient Care*/Continuity of Patient Care*/Continuity of Patient Care*/ethics ; Continuity of Patient Care*/Continuity of Patient Care*/Continuity of Patient Care*/organization & administration ; Early Termination of Clinical Trials*/Early Termination of Clinical Trials*/Early Termination of Clinical Trials*/ethics

  • Source: Heart (British Cardiac Society) [Heart] 2021 Jul; Vol. 107 (14), pp. 1109-1110. Date of Electronic Publication: 2021 May 21.Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9602087 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Periodical

COVID-19 impact on oncology clinical trials: a 1-year analysis.

Subjects: COVID-19*/COVID-19*/COVID-19*/epidemiology ; COVID-19*/COVID-19*/COVID-19*/prevention & control ; Clinical Trials as Topic*/Clinical Trials as Topic*/Clinical Trials as Topic*/classification

  • Source: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2021 Jun; Vol. 20 (6), pp. 415.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124171 Publication Model: Print Cited Medium: Internet ISSN: 1474-1784

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Academic Journal

Representativeness of Participants Eligible to Be Enrolled in Clinical Trials of Aducanumab for Alzheimer Disease Compared With Medicare Beneficiaries With Alzheimer Disease and Mild Cognitive Impairment.

  • Authors : Anderson TS; Division of General Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.; Ayanian JZ

Subjects: Early Termination of Clinical Trials*; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*therapeutic use

  • Source: JAMA [JAMA] 2021 Oct 26; Vol. 326 (16), pp. 1627-1629.Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN:

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Editorial & Opinion

Trial Discontinuation and Publication Outcome: Resource Wastage in Low Back Pain Research.

  • Authors : Tiefenbach J; Edinburgh Spinal Surgery Outcome Studies Group, Royal Infirmary of Edinburgh, Edinburgh, Scotland.; Cleveland Clinic, Cleveland, OH.

Subjects: Low Back Pain*/Low Back Pain*/Low Back Pain*/therapy; Humans ; Randomized Controlled Trials as Topic

  • Source: Spine [Spine (Phila Pa 1976)] 2023 Jul 01; Vol. 48 (13), pp. E219. Date of Electronic Publication: 2022 Nov 02.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7610646 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Early completion of phase I cancer clinical trials with Bayesian optimal interval design.

  • Authors : Kojima M; Biometrics Department, R&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan.; Department of Statistical Science, School of Multidisciplinary Sciences, The Graduate University for Advanced Studies, Tokyo, Japan.

Subjects: Early Termination of Clinical Trials* ; Models, Statistical* ; Neoplasms*/Neoplasms*/Neoplasms*/therapy

  • Source: Statistics in medicine [Stat Med] 2021 Jun 30; Vol. 40 (14), pp. 3215-3226. Date of Electronic Publication: 2021 Apr 12.Publisher: Wiley Country of Publication: England NLM ID: 8215016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0258

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Academic Journal

COVID-19 hits a trial: Arguments against hastily deviating from the plan.

  • Authors : Großhennig A; Institut für Biometrie, Medizinische Hochschule Hannover, Germany. Electronic address: .; Koch A

Subjects: COVID-19*/COVID-19*/COVID-19*/epidemiology ; COVID-19*/COVID-19*/COVID-19*/prevention & control ; Early Termination of Clinical Trials*/Early Termination of Clinical Trials*/Early Termination of Clinical Trials*/ethics

  • Source: Contemporary clinical trials [Contemp Clin Trials] 2020 Nov; Vol. 98, pp. 106155. Date of Publisher: Elsevier Country of Publication: United States NLM ID: 101242342 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

FDA's dilemma with the aducanumab approval: public pressure and hope, surrogate markers and efficacy, and possible next steps.

  • Authors : Rizk JG; University of Maryland, Baltimore, Department of Pharmaceutical Health Services Research, Baltimore, Maryland, USA .; Lewin JC

Subjects: Drug Approval* ; Antibodies, Monoclonal, Humanized*; Humans

  • Source: BMJ evidence-based medicine [BMJ Evid Based Med] 2023 Apr; Vol. 28 (2), pp. 78-82. Date of Electronic Publication: 2022 Apr 21.Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101719009 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Early termination of clinical trials in paediatrics.

  • Authors : Camara C; Graduate Tutor, Northumbria University.

Subjects: Early Termination of Clinical Trials* ; Pediatrics*; Child

  • Source: British journal of nursing (Mark Allen Publishing) [Br J Nurs] 2020 Jul 23; Vol. 29 (14), pp. 814-815.Publisher: MA Healthcare Country of Publication: England NLM ID: 9212059 Publication Model: Print Cited Medium: Internet ISSN: 0966-0461 (Print)

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Academic Journal

Clinical trials with sequential analysis that were early-stopped: How to interpret them?

  • Authors : Garegnani LI; Departamento de Investigación, Centro Cochrane Asociado, Instituto Universitario Hospital Italiano, Buenos Aires, Argentina.; Arancibia M

Subjects: Early Termination of Clinical Trials* ; Research Design*; Clinical Trials as Topic/Clinical Trials as Topic/Clinical Trials as Topic/*methods

  • Source: Medwave [Medwave] 2020 Jun 05; Vol. 20 (5), pp. e7930. Date of Electronic Publication: 2020 Jun 05.Publisher: Medwave Estudios Limitada Country of Publication: Chile NLM ID: 101581949 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  728 results for ""Early Termination of Clinical Trials""