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Agricola

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Agricola

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Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

• Authors : Scheuner, Donalyn; Mierde, Dirk Vander; Song, Benbo

• Source: Nature Medicine. July, 2005, Vol. 11 Issue 7, p757, 8 p.

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Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform

• Authors : De Keulenaer, Sarah; Hellemans, Jan; Lefever, Steve

• Source: BMC Medical Genomics. May 18, 2012, Vol. 5 Issue 1

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Detailed transcriptome atlas of the pancreatic beta cell.

• Authors : Kutlu, Burak; Burdick, David; Baxter, David

• Source: BMC Medical Genomics. January 15, 2009, Vol. 23.

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Development of a peptide-functionalized imaging nanoprobe for the targeting of (FXYD2)γa as a highly specific biomarker of pancreatic beta cells.

• Authors : Burtea, Carmen; Laurent, Sophie; Crombez, Deborah

• Source: Contrast Media & Molecular Imaging; Sep2015, Vol. 10 Issue 5, p398-412, 15p

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Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.

• Authors : Ortis F; Naamane N; Flamez D

• Source: Diabetes; Feb2010, Vol. 59 Issue 2, p358-374, 17p

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Cytokines Interleukin-1β and Tumor Necrosis Factor-α Regulate Different Transcriptional and Alternative Splicing Networks in Primary β-Cells.

• Authors : Ortis, Fernanda; Naamane, Najib; Flamez, Daisy

Subjects: CYTOKINES; PANCREATIC beta cells; DIABETES

• Source: Diabetes; Feb2010, Vol. 59 Issue 2, p358-374, 17p, 2 Diagrams, 1 Chart, 5 Graphs

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Double-Stranded RNA Induces Pancreatic β-Cell Apoptosis by Activation of the Toll-Like Receptor 3 and Interferon Regulatory Factor 3 Pathways.

• Authors : Dogusan, Zeynep; García, Mónica; Flamez, Daisy

Subjects: DOUBLE-stranded RNA; APOPTOSIS; PANCREATIC beta cells

• Source: Diabetes; May2008, Vol. 57 Issue 5, p1236-1245, 10p, 1 Diagram, 7 Graphs

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Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.

• Authors : Gysemans CA; Ladrière L; Callewaert H

• Source: Diabetes; Aug2005, Vol. 54 Issue 8, p2396-2403, 8p

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Disruption of the γ-Interferon Signaling Pathway at the Level of Signal Transducer and Activator of Transcription-1 Prevents Immune Destruction of β-cells.

• Authors : Gysemans, Conny A.; Ladrière, Laurence; Callewaert, Hanne

Subjects: PANCREATIC beta cells; DIABETES; INTERFERONS

• Source: Diabetes; Aug2005, Vol. 54 Issue 8, p2396-2402, 8p, 1 Chart, 5 Graphs

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Essential role of chicken ovalbumin upstream promoter-transcription factor II in insulin secretion and insulin sensitivity revealed by conditional gene knockout.

• Authors : Bardoux, Pascale; Zhang, Pili; Flamez, Daisy

Subjects: TRANSCRIPTION factors; BLOOD sugar; GLUCOSE

• Source: Diabetes; May2005, Vol. 54 Issue 5, p1357-1363, 7p, 4 Charts, 3 Graphs

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Glucose-Regulated Gene Expression Maintaining the Glucose-Responsive State of Β-Cells.

• Authors : Schuit, Frans; Flamez, Daisy; De Vos, Anick

Subjects: GENETICS of diabetes; GENE expression

• Source: Diabetes; Dec2002 Supplement 3, Vol. 51, pS326-S332, 7p, 2 Diagrams, 2 Graphs

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Critical role for cataplerosis via citrate in glucose-regulated insulin release.

• Authors : Flamez, Daisy; Berger, Veerle; Kruhøffer, Mogens

Subjects: MECHANISM of action for insulin; GLUCOSE

• Source: Diabetes; Jul2002, Vol. 51 Issue 7, p2018-2024, 7p, 1 Diagram, 3 Graphs

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Altered cAMP and Ca[sup 2+] signaling in mouse pancreatic islets with glucagon-like Peptide-1 receptor null phenotype.

• Authors : Flamez, Daisy; Gilon, Patrick; Moens, Karen

Subjects: PEPTIDES; ISLANDS of Langerhans

• Source: Diabetes; Oct99, Vol. 48 Issue 10, p1979, 8p, 7 Graphs

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Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.

• Authors : Pederson, Raymond A.; Satkunarajah, Malathy; McIntosh, Christopher H.S.

Subjects: PEPTIDES; INSULIN; GASTROINTESTINAL system

• Source: Diabetes; Jul1998, Vol. 47 Issue 7, p1046-1052, 7p, 11 Graphs

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Mouse pancreatic beta-cells exhibit preserved glucose competence after disruption of the glucagon-like peptide-1 receptor gene.

• Authors : Flamez, Daisy; Van Breusegem, An; Scrocchi, Louise A.

Subjects: PEPTIDES; ISLANDS of Langerhans

• Source: Diabetes; Apr1998, Vol. 47 Issue 4, p646-652, 7p, 6 Color Photographs, 3 Black and White Photographs, 1 Diagram, 2 Charts, 2 Graphs

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Dual glucagon recognition by pancreatic beta-cells via glucagon and glucagon-like peptide 1 receptors.

• Authors : Moens, Karen; Flamez, Daisy; Van Schravendijk, C.

Subjects: GLUCAGON; PEPTIDES; PANCREATIC beta cells

• Source: Diabetes; Jan1998, Vol. 47 Issue 1, p66-72, 7p, 2 Charts, 6 Graphs

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Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells.

• Authors : Moens, Karen; Heimberg, Harry; Flamez, Daisy

• Source: Diabetes; Feb1996, Vol. 45 Issue 2, p257-261, 5p, 3 Graphs

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Identification of New Pancreatic Beta Cell Targets for In Vivo Imaging by a Systems Biology Approach

• Authors : Bouckenooghe, Thomas; Flamez, Daisy; Ortis, Fernanda

• Source: Current Pharmaceutical Design; May 2010, Vol. 16 Issue: 14 p1609-1618, 10p

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Proteomics Analysis of Cytokine-induced Dysfunction and Death in Insulin-producing INS-1E Cells

• Authors : D'Hertog, Wannes; Overbergh, Lut; Lage, Kasper

• Source: Molecular and Cellular Proteomics (MCP Online); December 2007, Vol. 6 Issue: 12 p2180-2199, 20p

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T1DBase, a community web-based resource for type 1 diabetes research.

• Authors : Smink, Luc J.; Helton, Erin M.; Healy, Barry C.

• Source: Nucleic Acids Research; Jan2005, Vol. 33 Issue suppl 1, pd544-d549, 1p

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Prior in vitro exposure to GLP-1 with or without GIP can influence the subsequent beta cell responsiveness

• Authors : Delmeire, Dominique¹; Flamez, Daisy¹; Moens, Karen¹

Subjects: *PANCREATIC beta cells; *ISLANDS of Langerhans; *PEPTIDES

• Source: Biochemical Pharmacology. Jul2004, Vol. 68 Issue 1, p33-39. 7p.

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The AMP-activated protein kinase α2 catalytic subunit controls whole-body insulin sensitivity.

• Authors : Violett, Benoit; Andreelli, Fabrizio; Jorgensen, Sebastian B.

Subjects: PROTEIN kinases; PHYSIOLOGY

• Source: Journal of Clinical Investigation. 1/1/2003, Vol. 111 Issue 1, p91. 8p. 1 Diagram, 3 Charts, 4 Graphs.

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A Globin in the Nucleus!

• Authors : Geuens, Eva¹; Brouns, Inge¹; Flamez, Daisy¹

Subjects: *IMMUNOCYTOCHEMISTRY; *GLOBIN; *CELL nuclei

• Source: Journal of Biological Chemistry. 8/15/2003, Vol. 278 Issue 33, p30417-30420. 4p. 1 Diagram.

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