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Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes

• Authors : Barak, Oren; Lovelace, Tyler; Piekos, Samantha

• Source: BMC Medicine. September 8, 2023, Vol. 21 Issue 1

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A framework towards digital twins for type 2 diabetes.

• Authors : Yue Zhang; Guangrong Qin; Aguilar, Boris

Subjects: TYPE 2 diabetes; MACHINE learning; DIGITAL twins

• Source: Frontiers in Digital Health; 2024, p1-10, 10p

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The effect of maternal SARS-CoV-2 infection timing on birth outcomes: a retrospective multicentre cohort study.

• Authors : Piekos, Samantha N; Roper, Ryan T; Hwang, Yeon Mi

• Source: The Lancet. 2022, Vol. 4, Issue 2.

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The transition from genomics to phenomics in personalized population health

• Authors : Yurkovich, James T.; Evans, Simon J.; Rappaport, Noa

• Source: Nature Reviews Genetics; April 2024, Vol. 25 Issue: 4 p286-302, 17p

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Circulating cell-free mitochondrial DNA levels and glucocorticoid sensitivity in a cohort of male veterans with and without combat-related PTSD.

• Authors : Blalock, Zachary N.; Wu, Gwyneth W. Y; Lindqvist, Daniel

• Source: Translational Psychiatry; 1/10/2024, Vol. 14 Issue 1, p1-11, 11p

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A Remotely Coached Multimodal Lifestyle Intervention for Alzheimer's Disease Ameliorates Functional and Cognitive Outcomes.

• Authors : Roach, Jared C.; Rapozo, Molly K.; Hara, Junko

Subjects: ALZHEIMER'S disease; COVID-19 pandemic; PERSONAL coaching

• Source: Journal of Alzheimer's Disease; 2023, Vol. 96 Issue 2, p591-607, 17p

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A systems approach to clinical oncology uses deep phenotyping to deliver personalized care

• Authors : Yurkovich, James T.; Tian, Qiang; Price, Nathan D.

• Source: Nature Reviews Clinical Oncology. March 2020, Vol. 17 Issue 3, p183, 12 p.

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Reply to "Precision medicine in the clouds".

• Authors : Magis, Andrew T; Earls, John C; Glusman, Gustavo

• Source: Nature Biotechnology. 2018, Vol. 36, Issue 8, pages. 3

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A wellness study of 108 individuals using personal, dense, dynamic data clouds.

• Authors : Price, Nathan D; Magis, Andrew T; Earls, John C

• Source: Nature Biotechnology. 2017, Vol. 35, Issue 8, pages. 10

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Blood Is a Window into Health and Disease

• Authors : Yurkovich, James T.; Hood, Leroy

• Source: Clinical Chemistry. Oct, 2019, Vol. 65 Issue 10, p1204, 3 p.

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A Blueprint for Systems Biology

• Authors : Ideker, Trey; Hood, Leroy

• Source: Clinical Chemistry. Feb, 2019, Vol. 65 Issue 2, p342, 3 p.

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A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data.

• Authors : Hu, Hao; Roach, Jared C.; Coon, Hilary

• Source: Nature Biotechnology. 2014, Vol. 32, Issue 7, pages. 10

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Editorial: Translational phenomics and its applications in immunotherapy.

• Authors : Hai Fang; Liye Chen; Hood, Leroy

Subjects: IMMUNOTHERAPY; SYSTEMS biology; TRANSLATIONAL research

• Source: Frontiers in Immunology; 2023, p1-3, 3p

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Agricola

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Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.

• Authors : Baloni, Priyanka; Arnold, Matthias; Buitrago, Luna

Subjects: ALZHEIMER'S disease; METABOLIC flux analysis; SPHINGOMYELIN

• Source: Communications Biology; 10/8/2022, Vol. 5 Issue 1, p1-13, 13p

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Whole genome sequence and comparative analysis of Borrelia burgdorferi MM1

• Authors : Jabbari, Neda; Glusman, Gustavo; Joesch-Cohen, Lena M.

• Source: PLoS ONE. June 11, 2018, Vol. 13 Issue 6, e0198135

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Population-specific genetic modification of Huntington's disease in Venezuela

• Authors : Chao, Michael J.; Kim, Kyung-Hee; Shin, Jun Wan

• Source: PLoS Genetics. May 11, 2018, Vol. 14 Issue 5, e1007274

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Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention

• Authors : Watanabe, Kengo; Wilmanski, Tomasz; Diener, Christian

• Source: Nature Medicine; 20230101, Issue: Preprints p1-13, 13p

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Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood.

• Authors : Fan, Rong; Vermesh, Ophir; Srivastava, Alok

• Source: Nature Biotechnology. 2008, Vol. 26, Issue 12, pages. 6

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Direct multiplexed measurement of gene expression with color-coded probe pairs.

• Authors : Geiss, Gary K.; Bumgarner, Roger E.; Birditt, Brian

• Source: Nature Biotechnology. 2008, Vol. 26, Issue 3, pages. 10

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Systems Medicine and the Emergence of Proactive P4 Medicine

• Authors : Brogaard Kristin; Flores Mauricio; Hood Leroy

• Source: Handbook of Systems Biology.

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Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.

• Authors : Heath, Laura; Earls, John C.; Magis, Andrew T.

Subjects: DISEASE risk factors; METABOLOMICS; GENETIC variation

• Source: Scientific Reports; 4/12/2022, Vol. 12 Issue 1, p1-17, 17p

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The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort

• Authors : Wei, Kuo-Chen; Chen, Chia-Yuan; Feng, Li-Ying

• Source: PLoS ONE. June 2, 2017, Vol. 12 Issue 6, e0178842

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Biological complexity under attack.

• Authors : Hood, Leroy

• Source: Genetic Engineering and Biotechnology News. 2011, Vol. 31, Issue 17, pages. 6

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Nanomedicine Targets CANCER.

• Authors : Heath, James R.; Davis, Mark E.; Hood, Leroy

Subjects: NANOMEDICINE; NANOTECHNOLOGY; CANCER prevention

• Source: Scientific American. Feb2009, Vol. 300 Issue 2, p44-51. 8p.

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Agricola

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The Coaching for Cognition in Alzheimer's (COCOA) trial: Study design.

• Authors : Roach, Jared C.; Hara, Junko; Fridman, Deborah

Subjects: ALZHEIMER'S disease; CLINICAL trials; EXPERIMENTAL design

• Source: Alzheimer's & Dementia: Translational Research & Clinical Interventions; 2022, Vol. 8 Issue 1, p1-12, 12p

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Predictive, personalized, preventive, participatory (P4) cancer medicine

• Authors : Hood, Leroy; Friend, Stephen H.

• Source: Nature Reviews Clinical Oncology. March 2011, Vol. 8 Issue 3, p184, 4 p.

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The impact of systems approaches on biological problems in drug discovery.

• Authors : Hood, Leroy; Perlmutter, Roger M

• Source: Nature Biotechnology. 2004, Vol. 22, Issue 10, pages. 3

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Blood Is a Window into Health and Disease.

• Authors : Yurkovich, James, T.; Hood, Leroy

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Evolutionary history of Tibetans inferred from whole-genome sequencing

• Authors : Hu, Hao; Petousi, Nayia; Glusman, Gustavo

• Source: PLoS Genetics. April 27, 2017, Vol. 13 Issue 4, e1006675

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Predictive Big Data Analytics: A Study of Parkinson's Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations

• Authors : Dinov, Ivo D.; Heavner, Ben; Tang, Ming

• Source: PLoS ONE. August 5, 2016, Vol. 11 Issue 8, e0157077

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Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans.

• Authors : Diener, Christian; Shizhen Qin; Yong Zhou

• Source: MSystems; Oct2021, Vol. 6 Issue 5, p1-12, 12p

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iNetModels 2.0: an interactive visualization and database of multi-omics data.

• Authors : Arif, Muhammad; Zhang, Cheng; Li, Xiangyu

• Source: Nucleic Acids Research; 7/2/2021, Vol. 49 Issue W1, pW271-W276, 6p

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The geometry of clinical labs and wellness states from deeply phenotyped humans.

• Authors : Zimmer, Anat; Korem, Yael; Rappaport, Noa

Subjects: GEOMETRY; PHENOTYPES; CLINICAL pathology

• Source: Nature Communications; 6/11/2021, Vol. 12 Issue 1, p1-13, 13p

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