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Academic Journal

Construction of viral-based expression vectors for high-level production of human interferon alpha 2b in plants.

  • Authors : Sindarovska Y; Department of Genetic Engineering, Institute of Cell Biology and Genetic Engineering of NAS of Ukraine, Akad. Zabolotnogo Str., 148, Kyiv, 03148, Ukraine. .; Kuchuk M

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/genetics ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/metabolism ; Genetic Vectors*

  • Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2024 Feb 23; Vol. 108 (1), pp. 229. Date of Electronic Publication: 2024 Feb 23.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Detection of interferon alpha and beta receptor subunit 1 (IFNAR1) loss-of-function Glu386∗ variant by tri-allelic genotyping.

  • Authors : Woon ST; Molecular Immunology, LabPLUS, Te Whatu Ora, Health New Zealand Te Toka Tumai Auckland, New Zealand; Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand. Electronic address: .

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/genetics ; Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/genetics; Humans

  • Source: Pathology [Pathology] 2024 Feb; Vol. 56 (1), pp. 92-97. Date of Electronic Publication: 2023 Oct 29.Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 0175411 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Cytokine mRNA Expression Profile in Target Organs of IFNAR (-/-) Mice Infected with African Horse Sickness Virus.

  • Authors : Calvo-Pinilla E; Centro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Consejo Superior de Investigaciones Científicas (INIA-CSIC), 28130 Valdeolmos, Spain.; Jiménez-Cabello L

Subjects: African Horse Sickness*/African Horse Sickness*/African Horse Sickness*/genetics ; African Horse Sickness Virus*/African Horse Sickness Virus*/African Horse Sickness Virus*/metabolism ; African Horse Sickness Virus*/African Horse Sickness Virus*/African Horse Sickness Virus*/pathogenicity

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 08; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Safety, Tolerability, Pharmacokinetics, and Immunogenicity of the Anti-IFNAR1 Monoclonal Antibody QX006N: A First-in-Human Single Ascending Dose Study in Healthy Chinese Volunteers.

  • Authors : Li X; Phase I Clinical Trial Center, First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, 130021, China.; Li B

Subjects: Antibodies, Monoclonal*/Antibodies, Monoclonal*/Antibodies, Monoclonal*/adverse effects ; Antibodies, Monoclonal*/Antibodies, Monoclonal*/Antibodies, Monoclonal*/pharmacokinetics ; Receptor, Interferon alpha-beta*

  • Source: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy [BioDrugs] 2024 Mar; Vol. 38 (2), pp. 313-321. Date of Electronic Publication: 2023 Dec 27.Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9705305 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-α2a.

Subjects: HIV Infections*/HIV Infections*/HIV Infections*/drug therapy ; HIV-1*/HIV-1*/HIV-1*/genetics ; Panobinostat*/Panobinostat*/Panobinostat*/therapeutic use

  • Source: Cell [Cell] 2024 Feb 29; Vol. 187 (5), pp. 1238-1254.e14. Date of Electronic Publication: 2024 Feb 17.Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus.

  • Authors : Fujii H; The Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime, 794-8555, Japan; Department of Virology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan. Electronic address: .

Subjects: Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/genetics ; Interferon Type I* ; Bunyaviridae*Heartland virus

  • Source: Virus research [Virus Res] 2024 Feb; Vol. 340, pp. 199301. Date of Electronic Publication: 2023 Dec 16.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8410979 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

IFNAR2 relevance in the clinical outcome of individuals with severe COVID-19.

Subjects: COVID-19*/COVID-19*/COVID-19*/genetics ; COVID-19*/COVID-19*/COVID-19*/mortality ; Interferon Type I*/Interferon Type I*/Interferon Type I*/genetics

  • Source: Frontiers in immunology [Front Immunol] 2022 Jul 29; Vol. 13, pp. 949413. Date of Electronic Publication: 2022 Jul 29 (Print Publication: 2022).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

[Progress in the clinical cure of the population of inactive hepatitis B surface antigen carriers].

  • Authors : Mo ZS; Department of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China.; Gao ZL

Subjects: Hepatitis B Surface Antigens* ; Interferon-alpha*

  • Source: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology [Zhonghua Gan Zang Bing Za Zhi] 2023 Dec 20; Vol. 31 (12), pp. 1336-1339.Publisher: Chongqing yi ke da xue, di 2 lin chuang xue yuan Bing du xing gan yan yan jiu suo Country of Publication: China NLM ID: 9710009 Publication Model:

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Academic Journal

[Interferon-α mediating the functional damage of CD56 dim CD57 + natural killer cells in peripheral blood of systemic lupus erythematosuss].

  • Authors : Zhao XG; Department of Immunology, College of Basic Medical Science, Dalian Medical University, Dalian 116044, Liaoning, China.; Liu JQ

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/pharmacology ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/metabolism ; Lupus Erythematosus, Systemic*

  • Source: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences [Beijing Da Xue Xue Bao Yi Xue Ban] 2023 Dec 18; Vol. 55 (6), pp. 975-981.Publisher: Beijing da xue Country of Publication: China NLM ID: 101125284 Publication Model: Print Cited Medium: Print ISSN: 1671-167X (Print)

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Academic Journal

Engineering a New IFN-ApoA-I Fusion Protein with Low Toxicity and Prolonged Action.

  • Authors : Miroshnichenko S; Federal Research Center of Fundamental and Translational Medicine (FRC FTM), Timakova str., 2, 630117 Novosibirsk, Russia.; Pykhtina M

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/genetics ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/pharmacology ; Apolipoproteins A*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 08; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Inhibition of human cytomegalovirus replication by interferon alpha can involve multiple anti-viral factors.

  • Authors : Chowdhury S; Institute of Infection & Immunity, St George's, University of London, London, UK.; Latham KA

Subjects: Cytomegalovirus*/Cytomegalovirus*/Cytomegalovirus*/physiology ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/pharmacology; Humans

  • Source: The Journal of general virology [J Gen Virol] 2023 Dec; Vol. 104 (12).Publisher: Microbiology Society Country of Publication: England NLM ID: 0077340 Publication Model: Print Cited Medium: Internet ISSN: 1465-2099

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Academic Journal

Upregulated SPAG6 correlates with increased STAT1 and is associated with reduced sensitivity of interferon-α response in BCR::ABL1 negative myeloproliferative neoplasms.

  • Authors : Ding L; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Hematology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/pharmacology ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

  • Source: Cancer science [Cancer Sci] 2023 Nov; Vol. 114 (11), pp. 4445-4458. Date of Electronic Publication: 2023 Sep 08.Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic

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Academic Journal

RanBP2/Nup358 Mediates Sumoylation of STAT1 and Antagonizes Interferon-α-Mediated Antiviral Innate Immunity.

  • Authors : Li J; Department of Immunology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350108, China.; Su L

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/pharmacology ; Virus Diseases*; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 25; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

[A study of the clinical curative effect of nucleos(t)ide analogues treated to pegylated interferon-α add-on therapy in patients with chronic hepatitis B].

  • Authors : Liang H; Department of Infectious Diseases, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.; Wang C

Subjects: Hepatitis B, Chronic*/Hepatitis B, Chronic*/Hepatitis B, Chronic*/drug therapy ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/therapeutic use ; Polyethylene Glycols*/Polyethylene Glycols*/Polyethylene Glycols*/therapeutic use

  • Source: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology [Zhonghua Gan Zang Bing Za Zhi] 2023 Dec 20; Vol. 31 (12), pp. 1297-1305.Publisher: Chongqing yi ke da xue, di 2 lin chuang xue yuan Bing du xing gan yan yan jiu suo Country of Publication: China NLM ID: 9710009 Publication Model:

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Academic Journal

Desmethoxycurcumin aids IFNα's anti-HBV activity by antagonising CRYAB reduction and stabilising IFNAR1 protein.

  • Authors : Wei J; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Deng X

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/pharmacology ; Hepatitis B virus*/Hepatitis B virus*/Hepatitis B virus*/physiology; Curcumin/Curcumin/Curcumin/*analogs & derivatives

  • Source: Journal of drug targeting [J Drug Target] 2023 Dec; Vol. 31 (9), pp. 976-985. Date of Electronic Publication: 2023 Nov 16.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9312476 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lactate inhibits interferon-α response in ovarian cancer by inducing STAT1 ubiquitin degradation.

  • Authors : Dong X; Central Laboratory of Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde Foshan), Foshan 528300, Guangdong, China.; Lin C

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/metabolism ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/genetics; Humans

  • Source: International immunopharmacology [Int Immunopharmacol] 2023 Dec; Vol. 125 (Pt A), pp. 111099. Date of Electronic Publication: 2023 Oct 31.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chronic IFNα treatment induces leukopoiesis, increased plasma succinate and immune cell metabolic rewiring.

  • Authors : Yennemadi AS; TB Immunology Group, Department of Clinical Medicine, Trinity Translational Medicine Institute, School of Medicine, Trinity College Dublin, The University of Dublin, Dublin, Ireland.; Jameson G

Subjects: Succinic Acid*/Succinic Acid*/Succinic Acid*/metabolism ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/pharmacology; Humans

  • Source: Cellular immunology [Cell Immunol] 2023 Aug; Vol. 390, pp. 104741. Date of Electronic Publication: 2023 Jun 20.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1246405 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

CXCL13 variant predicts pegylated-interferon α treatment response in HBeAg-positive chronic hepatitis B patients.

  • Authors : Luo M; State Key Laboratory of Organ Failure Research, Guangdong Key Laboratory of Viral Hepatitis Research, Institutes of Liver Diseases Research of Guangdong Province, Department of Infectious Diseases and Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou, China.; The Key Laboratory of Molecular Pathology (Hepatic Diseases) of Guangxi, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.

Subjects: Chemokine CXCL13*/Chemokine CXCL13*/Chemokine CXCL13*/genetics ; Hepatitis B, Chronic*/Hepatitis B, Chronic*/Hepatitis B, Chronic*/drug therapy ; Hepatitis B, Chronic*/Hepatitis B, Chronic*/Hepatitis B, Chronic*/genetics

  • Source: Journal of medical virology [J Med Virol] 2023 Jul; Vol. 95 (7), pp. e28963.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071

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Academic Journal

Elevated Levels of Interferon-α Act Directly on B Cells to Breach Multiple Tolerance Mechanisms Promoting Autoantibody Production.

  • Authors : Ferri DM; Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Nassar C

Subjects: Interferon-alpha* ; Lupus Erythematosus, Systemic*; Animals

  • Source: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2023 Sep; Vol. 75 (9), pp. 1542-1555. Date of Electronic Publication: 2023 Jun 30.Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Immune modulation in chronic myeloid leukaemia patients treated with nilotinib and interferon-alpha.

  • Authors : Irani YD; Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.; The University of Adelaide, School of Medicine, Adelaide, South Australia, Australia.

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/therapeutic use ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy; Humans

  • Source: British journal of haematology [Br J Haematol] 2023 Sep; Vol. 202 (6), pp. 1127-1136. Date of Electronic Publication: 2023 Jul 22.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of interferon-α on COVID-19 in-hospital mortality: a large-scale propensity score-matched study.

  • Authors : Pourhoseingholi MA; Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Javazm AR

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/therapeutic use ; COVID-19*; Humans

  • Source: European cytokine network [Eur Cytokine Netw] 2023 Sep 01; Vol. 34 (2), pp. 10-19.Publisher: John Libbey Eurotext Ltd Country of Publication: France NLM ID: 9100879 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Interleukin-36γ is causative for liver damage upon infection with Rift Valley fever virus in type I interferon receptor-deficient mice.

  • Authors : Anzaghe M; Division of Immunology, Paul-Ehrlich-Institut, Langen, Germany.; Niles MA

Subjects: Interleukin-1* ; Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/Receptor, Interferon alpha-beta*/genetics ; Rift Valley Fever*/Rift Valley Fever*/Rift Valley Fever*/immunology

  • Source: Frontiers in immunology [Front Immunol] 2023 Sep 01; Vol. 14, pp. 1194733. Date of Electronic Publication: 2023 Sep 01 (Print Publication: 2023).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Time-dependent recruitment of GAF, ISGF3 and IRF1 complexes shapes IFNα and IFNγ-activated transcriptional responses and explains mechanistic and functional overlap.

  • Authors : Sekrecka A; Human Molecular Genetics Research Unit, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, Poznan, Poland.; Kluzek K

Subjects: Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/pharmacology ; Interferon-alpha*/Interferon-alpha*/Interferon-alpha*/genetics ; Interferon Type I*/Interferon Type I*/Interferon Type I*/metabolism

  • Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2023 Jun 22; Vol. 80 (7), pp. 187. Date of Electronic Publication: 2023 Jun 22.Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071

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Academic Journal

A genetic variant of CXCR4 predicts pegylated interferon-alpha treatment response in HBeAg-positive chronic hepatitis B patients.

  • Authors : Luo M; State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University , Guangzhou, China.; Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University , Guangzhou, China.

Subjects: Hepatitis B*/Hepatitis B*/Hepatitis B*/drug therapy ; Hepatitis B, Chronic*/Hepatitis B, Chronic*/Hepatitis B, Chronic*/drug therapy; Humans

  • Source: Journal of clinical microbiology [J Clin Microbiol] 2024 Feb 14; Vol. 62 (2), pp. e0139623. Date of Electronic Publication: 2024 Jan 23.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Tissue factor binds to and inhibits interferon-α receptor 1 signaling.

  • Authors : Manoharan J; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostic, University Hospital, Leipzig, Germany.; Rana R

Subjects: Signal Transduction* ; Thromboplastin*/Thromboplastin*/Thromboplastin*/genetics; Animals

  • Source: Immunity [Immunity] 2024 Jan 09; Vol. 57 (1), pp. 68-85.e11. Date of Electronic Publication: 2023 Dec 22.Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-25 of  36,471 results for ""INTERFERON alpha""