Search Results

Kidney Outcomes and Preservation of Kidney Function With Obinutuzumab in Patients With Lupus Nephritis: A Post Hoc Analysis of the NOBILITY Trial.

• Authors : Rovin, Brad H.; Furie, Richard A.; Ross Terres, Jorge A.

Subjects: KIDNEY physiology; THERAPEUTIC use of monoclonal antibodies; STATISTICS

• Source: Arthritis & Rheumatology; Feb2024, Vol. 76 Issue 2, p247-254, 8p

Record details

Clinical and Biomarker Responses to BI 655064, an Antagonistic Anti‐CD40 Antibody, in Patients With Active Lupus Nephritis: A Randomized, Double‐Blind, Placebo‐Controlled, Phase II Trial.

• Authors : Jayne, David R.; Steffgen, Jürgen; Romero‐Diaz, Juanita

Subjects: THERAPEUTIC use of monoclonal antibodies; GLUCOCORTICOIDS; DRUG efficacy

• Source: Arthritis & Rheumatology; Nov2023, Vol. 75 Issue 11, p1983-1993, 11p

Record details

Complement inhibitors in pediatric kidney diseases: new therapeutic opportunities.

• Authors : Antonucci, Luca; Thurman, Joshua M.; Vivarelli, Marina

Subjects: PROTEINURIA; IMMUNOSUPPRESSIVE agents; LUPUS nephritisUNITED States. Food & Drug Administration

• Source: Pediatric Nephrology; May2024, Vol. 39 Issue 5, p1387-1404, 18p

Record details

The use of combination monoclonal antibody therapies in lupus—where are we now?

• Authors : Rua, Joana; Dall'Era, Maria; Isenberg, David

Subjects: THERAPEUTIC use of monoclonal antibodies; DRUG efficacy; RITUXIMAB

• Source: Rheumatology; May2023, Vol. 62 Issue 5, p1724-1729, 6p

Record details

A typical clinical manifestation of atypical underlying diagnosis: Answers.

• Authors : B, Nuzaimah; CJ, Nur Asyilla; MK, Anis Munirah

Subjects: THERAPEUTIC use of monoclonal antibodies; IMMUNOCHEMISTRY; LUPUS nephritis

• Source: Pediatric Nephrology; Nov2023, Vol. 38 Issue 11, p3615-3617, 3p, 2 Color Photographs

Record details

Lupus low disease activity state as a treatment target for pediatric patients with lupus nephritis.

• Authors : Kisaoglu, Hakan; Baba, Ozge; Kalyoncu, Mukaddes

Subjects: EVALUATION of medical care; HYPERTENSION; LUPUS nephritis

• Source: Pediatric Nephrology; Apr2023, Vol. 38 Issue 4, p1167-1175, 9p, 5 Charts

Record details

CCR2- and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis.

• Authors : Zoshima, Takeshi; Baba, Tomohisa; Tanabe, Yamato

Subjects: ENDOTHELIAL cells; GLOMERULAR filtration rate; LUPUS nephritis

• Source: Rheumatology; Jul2022, Vol. 61 Issue 7, p3033-3048, 16p

Record details

Lupus Nephritis: Improving Treatment Options.

• Authors : Kostopoulou, Myrto; Pitsigavdaki, Sofia; Bertsias, George

Subjects: DRUG approval; LUPUS nephritis; MONOCLONAL antibodies

• Source: Drugs; May2022, Vol. 82 Issue 7, p735-748, 14p

Record details

B-cell depletion with obinutuzumab for the treatment of proliferative lupus nephritis: a randomised, double-blind, placebo-controlled trial.

• Authors : Furie, Richard A.; Aroca, Gustavo; Cascino, Matthew D.

Subjects: THERAPEUTIC use of monoclonal antibodies; GLOMERULAR filtration rate; RESEARCH

• Source: Annals of the Rheumatic Diseases; Jan2022, Vol. 81 Issue 1, p100-107, 8p

Record details

T Helper 2-Associated Immunity in the Pathogenesis of Systemic Lupus Erythematosus.

• Authors : Ko, Haeun; Kim, Chan Johng; Im, Sin-Hyeog

Subjects: SYSTEMIC lupus erythematosus; IMMUNOGLOBULIN G; IMMUNITY

• Source: Frontiers in Immunology; 4/4/2022, Vol. 13, p1-9, 9p

Record details

Phase II randomised trial of type I interferon inhibitor anifrolumab in patients with active lupus nephritis.

• Authors : Jayne, David; Rovin, Brad; Mysler, Eduardo F.

Subjects: THERAPEUTIC use of monoclonal antibodies; GLUCOCORTICOIDS; RESEARCH

• Source: Annals of the Rheumatic Diseases; Apr2022, Vol. 81 Issue 4, p496-506, 66p

Record details

New and Old Anti-CD20 Monoclonal Antibodies for Nephrotic Syndrome. Where We Are?

• Authors : Basu, Biswanath; Angeletti, Andrea; Islam, Bilkish

Subjects: MONOCLONAL antibodies; NEPHROTIC syndrome; FOCAL segmental glomerulosclerosis

• Source: Frontiers in Immunology; 2/11/2022, Vol. 13, p1-9, 9p

Record details

Efficacy and safety of an anti‐CD20 monoclonal antibody, rituximab, for lupus nephritis: A meta‐analysis.

• Authors : Teng, Siyuan; Tian, Yu; Luo, Nan

Subjects: LUPUS nephritis; MONOCLONAL antibodies; RITUXIMAB

• Source: International Journal of Rheumatic Diseases; Feb2022, Vol. 25 Issue 2, p101-109, 9p

Record details

Anifrolumab: First Approval.

• Authors : Deeks, Emma D.

Subjects: THERAPEUTIC use of monoclonal antibodies; DRUG approval; INTRAVENOUS therapy

• Source: Drugs; Oct2021, Vol. 81 Issue 15, p1795-1802, 8p

Record details

The Type II Anti‐CD20 Antibody Obinutuzumab (GA101) Is More Effective Than Rituximab at Depleting B Cells and Treating Disease in a Murine Lupus Model.

• Authors : Marinov, Anthony D.; Wang, Haowei; Bastacky, Sheldon I.

Subjects: THERAPEUTIC use of monoclonal antibodies; DRUG efficacy; RITUXIMAB

• Source: Arthritis & Rheumatology; May2021, Vol. 73 Issue 5, p826-836, 11p

Record details

From sequential to combination and personalised therapy in lupus nephritis: moving towards a paradigm shift?

• Authors : Parodis, Ioannis; Houssiau, Frederic A.

Subjects: THERAPEUTIC use of monoclonal antibodies; RESEARCH; LUPUS nephritis

• Source: Annals of the Rheumatic Diseases; Jan2022, Vol. 81 Issue 1, p15-19, 5p

Record details

Patent Application Titled "Compositions And Methods Of Treating Lupus Nephritis" Published Online (USPTO 20240033351).

Subjects: PATENT applications; INTERNET publishing; LUPUS nephritis

• Source: Women's Health Weekly; 2/23/2024, p1937-1937, 1p

Record details

贝利尤单抗用于儿童系统性红斑狼疮的研究进展.

• Authors : 邓伟萍; 综述胡长平; 罗平

Subjects: SYSTEMIC lupus erythematosus; CHILD patients; BELIMUMABCHINA

• Source: Chinese Journal of Contemporary Pediatrics; Oct2021, Vol. 23 Issue 10, p1069-1074, 6p

Record details

Study Results from Osaka Medical and Pharmaceutical University in the Area of Lupus Published (A successful plasma exchange in bridging to rituximab for severe neuropsychiatric lupus and lupus nephritis with viral infections and aspiration...).

Subjects: VIRUS diseases; LUPUS nephritis; RITUXIMAB

• Source: Immunotherapy Weekly; 1/12/2024, p434-434, 1p

Record details

Mild Clinical Course of COVID-19 in 3 Patients Receiving Therapeutic Monoclonal Antibodies Targeting C5 Complement for Hematologic Disorders.

• Authors : Araten, David J.; Belmont, H. Michael; Schaefer-Cutillo, Julia

Subjects: COVID-19; MONOCLONAL antibodies; PATHOLOGY

• Source: American Journal of Case Reports; 9/12/2020, Vol. 21, p1-4, 4p

Record details

Monoclonal antibody therapy that targets phospholipid‐binding protein delays lupus activity in MRL/lpr mice.

• Authors : Mihaylova, Nikolina; Bradyanova, Silviya; Chipinski, Petroslav

Subjects: MONOCLONAL antibodies; ANTIBODY formation; INTERLEUKIN-21

• Source: Scandinavian Journal of Immunology; Sep2020, Vol. 92 Issue 3, p1-9, 9p

Record details

C1q A08 Is a Half-Cryptic Epitope of Anti-C1q A08 Antibodies in Lupus Nephritis and Important for the Activation of Complement Classical Pathway.

• Authors : Wu, Wen-Jun; Tan, Ying; Liu, Xiao-Ling

Subjects: ECULIZUMAB; LUPUS nephritis; COMPLEMENT activation

• Source: Frontiers in Immunology; 5/27/2020, Vol. 11, p1-11, 11p

Record details

Monoclonal anti‐dsDNA antibody 2C10 escorts DNA to intracellular DNA sensors in normal mononuclear cells and stimulates secretion of multiple cytokines implicated in lupus pathogenesis.

• Authors : Inoue, K.; Ishizawa, M.; Kubota, T.

Subjects: DNA antibodies; MONOCLONAL antibodies; TUMOR necrosis factors

• Source: Clinical & Experimental Immunology; Feb2020, Vol. 199 Issue 2, p150-162, 13p, 7 Graphs

Record details

2023 Lupus Nephritis Pipeline Report Reveals 20+ Companies and 25+ Promising Drugs in Development - ResearchAndMarkets.com.

Subjects: LUPUS nephritis; DRUG development; BLOOD proteins

• Source: Pharma Business Week; 8/8/2023, p70-70, 1p

Record details

Glomerular expression of matrix metalloproteinases in systemic lupus erythematosus in association with activity index and renal function.

• Authors : Adamidis, Konstantinos N.; Kopaka, Maria-Emmanouela; Petraki, Constantina

Subjects: LUPUS nephritis; MATRIX metalloproteinases; SYSTEMIC lupus erythematosus

• Source: Renal Failure; Nov2019, Vol. 41 Issue 1, p229-237, 9p, 1 Diagram, 5 Charts

Record details

Early onset neutropenia and thrombocytopenia following rituximab in lupus nephritis.

• Authors : Shah, Sanket; Kavadichanda, Chengappa G.; Belani, Pooja

Subjects: LUPUS nephritis; RITUXIMAB; SYSTEMIC lupus erythematosus

• Source: International Journal of Rheumatic Diseases; May2019, Vol. 22 Issue 5, p946-950, 5p

Record details

Clinical significance of serum and mesangial galactose-deficient IgA1 in patients with IgA nephropathy.

• Authors : Wada, Yukihiro; Matsumoto, Kei; Suzuki, Taihei

Subjects: GALACTOSE; LUPUS nephritis; MONOCLONAL antibodies

• Source: PLoS ONE; 11/2/2018, Vol. 13 Issue 11, p1-17, 17p

Record details

Ofatumumab for B cell depletion in patients with systemic lupus erythematosus who are allergic to rituximab.

• Authors : Masoud, Sherry; McAdoo, Stephen P; Bedi, Rachna

Subjects: THERAPEUTIC use of monoclonal antibodies; LUPUS nephritis; B cells

• Source: Rheumatology; Jul2018, Vol. 57 Issue 7, p1156-1161, 6p, 1 Chart, 1 Graph

Record details

Safety, pharmacokinetics and pharmacodynamics of single rising doses of BI 655064, an antagonistic anti-CD40 antibody in healthy subjects: a potential novel treatment for autoimmune diseases.

• Authors : Albach, Fredrik; Wagner, Frank; Hüser, Andreas

Subjects: AUTOIMMUNE diseases; MONOCLONAL antibodies; PHARMACOKINETICS

• Source: European Journal of Clinical Pharmacology; Feb2018, Vol. 74 Issue 2, p161-169, 9p, 2 Charts, 3 Graphs

Record details

A monoclonal antibody against CD86 and its protection in a murine lupus nephritis model of chronic graft-versus-host disease.

• Authors : Han, Lianhua; Shen, Lijun; Zhu, Ying

Subjects: GRAFT versus host disease; LUPUS nephritis; MONOCLONAL antibodies

• Source: Immunopharmacology & Immunotoxicology; Oct2017, Vol. 39 Issue 5, p285-291, 7p

Record details

Findings from University College London (UCL) Yields New Data on Lupus (Identification of Biomarkers To Stratify Response To B-cell- Targeted Therapies In Systemic Lupus Erythematosus: an Exploratory Analysis of a Randomised Controlled Trial).

Subjects: RANDOMIZED controlled trials; LUPUS nephritis; SYSTEMIC lupus erythematosusUNIVERSITY College, London

• Source: Immunotherapy Weekly; 2/14/2023, p700-700, 1p

Record details

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Treatment With Sirukumab (CNTO 136) in Patients With Active Lupus Nephritis.

• Authors : Rovin, Brad H.; van Vollenhoven, Ronald F.; Aranow, Cynthia

Subjects: CLINICAL medicine; CONFIDENCE intervals; DRUG side effects

• Source: Arthritis & Rheumatology; Sep2016, Vol. 68 Issue 9, p2174-2183, 10p

Record details

Editorial: A Stalemate in Lupus-Related End-Stage Renal Disease: Can We Do Better?

• Authors : Feldman, Candace H.; Costenbader, Karen H.

Subjects: THERAPEUTIC use of monoclonal antibodies; IMMUNOSUPPRESSIVE agents; DRUGS

• Source: Arthritis & Rheumatology; Jun2016, Vol. 68 Issue 6, p1323-1326, 4p

Record details

Systemic lupus erythematosus exacerbation following cessation of belimumab treatment.

• Authors : Furer, V; Zisman, D; Pokroy-Shapira, E

Subjects: SYSTEMIC lupus erythematosus; AUTOIMMUNE diseases; BELIMUMAB

• Source: Scandinavian Journal of Rheumatology; Mar2016, Vol. 45 Issue 2, p103-106, 4p

Record details

A peptide mimic blocks the cross-reaction of anti-DNA antibodies with glomerular antigens.

• Authors : Xia, Y.; Eryilmaz, E.; Der, E.

Subjects: LUPUS nephritis; ENZYME-linked immunosorbent assay; FLOW cytometry

• Source: Clinical & Experimental Immunology; Mar2016, Vol. 183 Issue 3, p369-379, 11p

Record details

Interleukin-17 in systemic lupus erythematosus: A comprehensive review.

• Authors : Li, Duo; Guo, Bin; Wu, Haijing

Subjects: SYSTEMIC lupus erythematosus; AUTOIMMUNE diseases; SKIN diseases

• Source: Autoimmunity; Sep2015, Vol. 48 Issue 6, p353-361, 9p

Record details

Efficacy of novel monoclonal antibody belimumab in the treatment of lupus nephritis.

• Authors : Frieri, Marianne; Heuser, William; Bliss, Joshua

Subjects: LUPUS nephritis; BELIMUMAB; THERAPEUTIC use of monoclonal antibodies

• Source: Journal of Pharmacology & Pharmacotherapeutics; Apr-Jun2015, Vol. 6 Issue 2, p71-76, 6p

Record details

Dramatic effects of eculizumab in a child with diffuse proliferative lupus nephritis resistant to conventional therapy.

• Authors : Coppo, Rosanna; Peruzzi, Licia; Amore, Alessandro

Subjects: SYSTEMIC lupus erythematosus diagnosis; SYSTEMIC lupus erythematosus treatment; COMPLEMENT (Immunology)

• Source: Pediatric Nephrology; Jan2015, Vol. 30 Issue 1, p167-172, 6p

Record details

Rituximab in Systemic Lupus Erythematosus and Lupus Nephritis.

• Authors : Beckwith, Hannah; Lightstone, Liz

Subjects: B cells; RITUXIMAB; ANTINEOPLASTIC agents

• Source: Nephron Clinical Practice; Jan2015, Vol. 128 Issue 3/4, p250-254, 5p

Record details

Update on Rituximab: An Established Treatment for All Immune-Mediated Kidney Diseases?

• Authors : Evans, Rhys; Salama, Alan D.

Subjects: VASCULAR diseases; MONOCLONAL antibodies; KIDNEY disease treatments

• Source: Nephron Clinical Practice; Jun2014, Vol. 126 Issue 3, p97-109, 13p

Record details

Formulary Drug Reviews - Belimumab.

• Authors : Cada, Dennis J.; Levien, Terri L.; Baker, Danial E.

Subjects: CENTRAL nervous system diseases; THERAPEUTICS; THERAPEUTIC use of monoclonal antibodies

• Source: Hospital Pharmacy; Jul2011, Vol. 46 Issue 7, p519-526, 8p

Record details

FDA Approves Benlysta for Children 5 Years and Up.

Subjects: KIDNEY disease prevention; DRUG approval; LUPUS nephritisUNITED States. Food & Drug Administration

• Source: Formulary Watch; 7/28/2022, p1-1, 1p

Record details

The treatment of systemic lupus proliferative nephritis.

• Authors : Punaro, Marilynn

Subjects: ADRENOCORTICAL hormones; ANTIMALARIALS; MONOCLONAL antibodies

• Source: Pediatric Nephrology; Nov2013, Vol. 28 Issue 11, p2069-2078, 10p, 1 Chart

Record details

Novel therapeutic agents in clinical development for systemic lupus erythematosus.

• Authors : Jordan, Natasha; Lutalo, Pamela M. K.; D'Cruz, David P.

Subjects: SYSTEMIC lupus erythematosus; IMMUNOSUPPRESSIVE agents; CUTANEOUS tuberculosis

• Source: BMC Medicine; 2013, Vol. 11 Issue 1, p1-11, 11p, 1 Chart

Record details

Anti-Idiotype scFv Localizes an Autoepitope in the Globular Domain of C1q.

• Authors : Todorova, Nadezhda; Rangelov, Miroslav; Bogoeva, Vanya

Subjects: DNA antibodies; RECOMBINANT antibodies; MOLECULAR dynamics

• Source: International Journal of Molecular Sciences; Aug2021, Vol. 22 Issue 15, p8288-8288, 1p

Record details

Rituximab: emerging treatment strategies of immune-mediated glomerular disease.

• Authors : Kattah, Andrea G.; Fervenza, Fernando C.

Subjects: RITUXIMAB; GLOMERULONEPHRITIS; MONOCLONAL antibodies

• Source: Expert Review of Clinical Immunology; Jul2012, Vol. 8 Issue 5, p413-421, 9p

Record details

New developments in the treatment of systemic lupus erythematosus.

• Authors : Tullus, Kjell

Subjects: IMMUNOLOGICAL adjuvants; THERAPEUTIC use of monoclonal antibodies; PEPTIDES

• Source: Pediatric Nephrology; May2012, Vol. 27 Issue 5, p727-732, 6p

Record details

Systemic Lupus Erythematosus.

Subjects: SYSTEMIC lupus erythematosus; RANDOMIZED controlled trials; MONOCLONAL antibodies

• Source: Current Medical Literature: Rheumatology; 2012, Vol. 31 Issue 1, p9-14, 6p

Record details

Induction of high-dose tolerance to the rat anti-mouse IL-6 receptor antibody in NZB/NZW F1 mice.

• Authors : Yoshida, Hiroto; Hashizume, Misato; Suzuki, Miho

Subjects: MONOCLONAL antibodies; LABORATORY mice; AUTOIMMUNE diseases

• Source: Rheumatology International; Nov2011, Vol. 31 Issue 11, p1445-1449, 5p, 1 Chart, 3 Graphs

Record details

A review of systemic lupus erythematosus and current treatment options.

• Authors : Bernknop, Allison; Rowley, Kristina; Bailey, Teresa

Subjects: THERAPEUTIC use of glucocorticoids; THERAPEUTIC use of monoclonal antibodies; NONSTEROIDAL anti-inflammatory agents

• Source: Formulary; May2011, Vol. 46 Issue 5, p178-194, 9p, 1 Color Photograph, 3 Charts

Record details