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Academic Journal

The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target.

  • Authors : Ng KP; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Medical School, Singapore, Singapore.; Manjeri A

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Arginase/Arginase/Arginase/*antagonists & inhibitors

  • Source: PloS one [PLoS One] 2018 Oct 11; Vol. 13 (10), pp. e0205254. Date of Electronic Publication: 2018 Oct 11 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors.

  • Authors : Ko TK; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore.; Chuah CT

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Benzamides/Benzamides/Benzamides/*pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*pharmacology

  • Source: Oncotarget [Oncotarget] 2014 Oct 15; Vol. 5 (19), pp. 9033-8.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer.

  • Authors : Ng KP; Cancer & Stem Cell Biology Signature Research Programme, Duke-National University of Singapore Graduate Medical School, Singapore.; Hillmer AM

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*genetics ; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*genetics

  • Source: Nature medicine [Nat Med] 2012 Mar 18; Vol. 18 (4), pp. 521-8. Date of Electronic Publication: 2012 Mar 18.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-3 of  3 results for ""Ng KP""