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Academic Journal

Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo.

  • Authors : Wang G; Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease of Sichuan Province, Drug Discovery Research Center, Southwest Medical University, Luzhou, China.; Laboratory for Cardiovascular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, China.

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Metformin/Metformin/Metformin/*pharmacology ; Oxidative Stress/Oxidative Stress/Oxidative Stress/*drug effects

  • Source: Cell death & disease [Cell Death Dis] 2022 Jan 10; Vol. 13 (1), pp. 29. Date of Electronic Publication: 2022 Jan 10.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Spironolactone Attenuates Methylglyoxal-induced Cellular Dysfunction in MC3T3-E1 Osteoblastic Cells.

  • Authors : Park SY; Department of Endocrinology and Metabolism, Kyung Hee University Hospital, Seoul, Korea.; Suh KS

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Protective Agents/Protective Agents/Protective Agents/*pharmacology ; Spironolactone/Spironolactone/Spironolactone/*pharmacology

  • Source: Journal of Korean medical science [J Korean Med Sci] 2021 Oct 04; Vol. 36 (38), pp. e265. Date of Electronic Publication: 2021 Oct 04.Publisher: Korean Academy of Medical Science Country of Publication: Korea (South) NLM ID: 8703518 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Methylglyoxal-derived hemoglobin advanced glycation end products induce apoptosis and oxidative stress in human umbilical vein endothelial cells.

  • Authors : Lee JH; College of Pharmacy, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Republic of Korea.; Samsuzzaman M

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Glycation End Products, Advanced/Glycation End Products, Advanced/Glycation End Products, Advanced/*toxicity ; Hemoglobins/Hemoglobins/Hemoglobins/*toxicity

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2021 Sep 30; Vol. 187, pp. 409-421. Date of Electronic Publication: 2021 Jul 13.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Molecular docking and dynamic studies of a potential therapeutic target inhibiting glyoxalase system: Metabolic action of the 3, 3 '- [3- (5-chloro-2-hydroxyphenyl) -3-oxopropane-1, 1-diyl] - Bis-4-hydroxycoumarin leads overexpression of the intracellular level of methylglyoxal and induction of a pro-apoptotic phenomenon in a hepatocellular carcinoma model.

  • Authors : Taïbi N; Centre de Recherche Scientifique et Technique en Analyses Physico-chimiques CRAPC, BP 384, Bou-Ismail, 42004, Tipaza, Algeria; Université des Sciences et de La Technologie Houari Boumediene (USTHB), Faculté des Sciences Biologiques (FSB), Laboratoire de Recherche sur Les Zones Arides, (LRZA), BP 32 El Alia 16111, Bab Ezzouar, 16111, Algeria. Electronic address: .

Subjects: Models, Molecular*; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*pathology

  • Source: Chemico-biological interactions [Chem Biol Interact] 2021 Aug 25; Vol. 345, pp. 109511. Date of Electronic Publication: 2021 May 11.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786

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Academic Journal

Pterostilbene prevents methylglyoxal-induced cytotoxicity in endothelial cells by regulating glyoxalase, oxidative stress and apoptosis.

  • Authors : Tang D; Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM and Engineering & Technology Research Center for Chinese Materia Medica Quality of Guangdong Province, Guangdong Pharmaceutical University, Guangzhou, 510006, China.; Xiao W

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cell Survival/Cell Survival/Cell Survival/*drug effects ; Lactoylglutathione Lyase/Lactoylglutathione Lyase/Lactoylglutathione Lyase/*metabolism

  • Source: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2021 Jul; Vol. 153, pp. 112244. Date ofPublisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Methylglyoxal-Derived Advanced Glycation End Product (AGE4)-Induced Apoptosis Leads to Mitochondrial Dysfunction and Endoplasmic Reticulum Stress through the RAGE/JNK Pathway in Kidney Cells.

  • Authors : Jeong SR; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Anam-Dong, Sungbuk-Gu, Seoul 02841, Korea.; Lee KW

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/drug effects ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 18; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Naringenin, a dietary flavanone, enhances insulin-like growth factor 1 receptor-mediated antioxidant defense and attenuates methylglyoxal-induced neurite damage and apoptotic death.

  • Authors : Tseng YT; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Hsu HT

Subjects: Antioxidants/Antioxidants/Antioxidants/*administration & dosage ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Flavanones/Flavanones/Flavanones/*administration & dosage

  • Source: Nutritional neuroscience [Nutr Neurosci] 2021 Jan; Vol. 24 (1), pp. 71-81. Date of Electronic Publication: 2019 Mar 22.Publisher: Taylor & Francis Country of Publication: England NLM ID: 100892202 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Autophagy Functions to Prevent Methylglyoxal-Induced Apoptosis in HK-2 Cells.

  • Authors : Park SH; Division of Food Functionality Research, Korea Food Research Institute, Wanju-gun, Jeollabuk-do 55365, Republic of Korea.; Department of Food Biotechnology, Korea University of Science and Technology, Wanju-gun, Jeollabuk-do 55365, Republic of Korea.

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Autophagy/Autophagy/Autophagy/*drug effects ; Pyruvaldehyde/Pyruvaldehyde/Pyruvaldehyde/*pharmacology

  • Source: Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2020 Jun 04; Vol. 2020, pp. 8340695. Date of Electronic Publication: 2020 Jun 04 (Print Publication: 2020).Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101479826 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Osteomeles schwerinae Extract and Its Major Compounds Inhibit Methylglyoxal-Induced Apoptosis in Human Retinal Pigment Epithelial Cells.

  • Authors : Pyun BJ; Herbal Medicine Division, Korea Institute of Oriental Medicine, 1672 Yuseongdae-ro, Yuseong-gu, Daejeon 34054, Korea.; Kim YS

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Plant Extracts/Plant Extracts/Plant Extracts/*pharmacology ; Plant Leaves/Plant Leaves/Plant Leaves/*chemistry

  • Source: Molecules (Basel, Switzerland) [Molecules] 2020 Jun 03; Vol. 25 (11). Date of Electronic Publication: 2020 Jun 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Cyanidin Attenuates Methylglyoxal-Induced Oxidative Stress and Apoptosis in INS-1 Pancreatic β-Cells by Increasing Glyoxalase-1 Activity.

  • Authors : Suantawee T; Program in Biomedical Sciences, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand.; Phytochemical and Functional Food Research Unit for Clinical Nutrition, Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

Subjects: Anthocyanins/Anthocyanins/Anthocyanins/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Gene Expression/Gene Expression/Gene Expression/*drug effects

  • Source: Nutrients [Nutrients] 2020 May 06; Vol. 12 (5). Date of Electronic Publication: 2020 May 06.Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  139 results for ""PYRUVALDEHYDE""