Search Results

The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT).

• Authors : Pharaoh G; Department of Radiology, University of Washington, Seattle, WA, 98195, USA.; Kamat V

Subjects: Mitochondria*/Mitochondria*/Mitochondria*/metabolism ; Adenosine Triphosphate*/Adenosine Triphosphate*/Adenosine Triphosphate*/metabolism; Adenosine Diphosphate/Adenosine Diphosphate/Adenosine Diphosphate/pharmacology

• Source: GeroScience [Geroscience] 2023 Dec; Vol. 45 (6), pp. 3529-3548. Date of Electronic Publication: 2023 Jul 18.Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium:

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A novel mitochondrial complex I ROS inhibitor partially improves muscle regeneration in adult but not old mice.

• Authors : Pharaoh G; Department of Radiology, University of Washington School of Medicine, USA.; Ostrom EL

Subjects: Muscle, Skeletal* ; Mitochondria, Muscle*; Mice

• Source: Redox biology [Redox Biol] 2023 Aug; Vol. 64, pp. 102770. Date of Electronic Publication: 2023 Jun 02.Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Elamipretide Improves ADP Sensitivity in Aged Mitochondria by Increasing Uptake through the Adenine Nucleotide Translocator (ANT).

• Authors : Pharaoh G; Department of Radiology, University of Washington, Seattle, Washington, 98195, USA.; Kamat V

• Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 03. Date of Electronic Publication: 2023 Feb 03.Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not

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Determining the contributions of protein synthesis and breakdown to muscle atrophy requires non-steady-state equations.

• Authors : Kobak KA; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland.

Subjects: Muscle Denervation* ; Muscular Atrophy*/Muscular Atrophy*/Muscular Atrophy*/pathology; Animals

• Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2021 Dec; Vol. 12 (6), pp. 1764-1775. Date of Electronic Publication: 2021 Aug 21.Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication

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Reduced adenosine diphosphate sensitivity in skeletal muscle mitochondria increases reactive oxygen species production in mouse models of aging and oxidative stress but not denervation.

• Authors : Pharaoh G; Physiology Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

• Source: JCSM rapid communications [JCSM Rapid Commun] 2021 Jan-Jun; Vol. 4 (1), pp. 75-89. Date of Electronic Publication: 2020 Dec 28.Publisher: Wiley Country of Publication: United States NLM ID: 101726459 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Restoration of Sarcoplasmic Reticulum Ca 2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice.

• Authors : Qaisar R; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.; Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah 27272, UAE.

Subjects: Aminoquinolines/Aminoquinolines/Aminoquinolines/*pharmacology ; Benzamides/Benzamides/Benzamides/*pharmacology ; Muscle Weakness/Muscle Weakness/Muscle Weakness/*prevention & control

• Source: International journal of molecular sciences [Int J Mol Sci] 2020 Dec 22; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Cancer cachexia in a mouse model of oxidative stress.

• Authors : Brown JL; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Lawrence MM

Subjects: Cachexia*/Cachexia*/Cachexia*/etiology ; Carcinoma, Lewis Lung*/Carcinoma, Lewis Lung*/Carcinoma, Lewis Lung*/complications; Animals

• Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2020 Dec; Vol. 11 (6), pp. 1688-1704. Date of Electronic Publication: 2020 Sep 12.Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication

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Targeting cPLA 2 derived lipid hydroperoxides as a potential intervention for sarcopenia.

• Authors : Pharaoh G; Physiology Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

Subjects: Lipid Peroxides/Lipid Peroxides/Lipid Peroxides/*metabolism ; Phospholipases A2/Phospholipases A2/Phospholipases A2/*metabolism ; Sarcopenia/Sarcopenia/Sarcopenia/*therapy

• Source: Scientific reports [Sci Rep] 2020 Aug 18; Vol. 10 (1), pp. 13968. Date of Electronic Publication: 2020 Aug 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia.

• Authors : Sataranatarajan K; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.; Pharaoh G

Subjects: Sarcopenia*/Sarcopenia*/Sarcopenia*/metabolism; Animals ; Metabolic Networks and Pathways

• Source: GeroScience [Geroscience] 2020 Aug; Vol. 42 (4), pp. 1101-1118. Date of Electronic Publication: 2020 May 12.Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium:

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Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function.

• Authors : Pharaoh G; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.

Subjects: Aging/Aging/Aging/*metabolism ; Brain/Brain/Brain/*metabolism ; Insulin-Like Growth Factor I/Insulin-Like Growth Factor I/Insulin-Like Growth Factor I/*deficiency

• Source: Molecular neurobiology [Mol Neurobiol] 2020 Mar; Vol. 57 (3), pp. 1317-1331. Date of Electronic Publication: 2019 Nov 15.Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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