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Academic Journal

Agonists of the P2Y[sub AC]-receptor activate MAP kinase by a ras-independent pathway in rat C6 glioma.

Subjects: GLIOMAS; RATS; NUCLEOTIDES

  • Source: Journal of Neurochemistry; 9/15/2001, Vol. 78 Issue 6, p1325-1338, 14p, 9 Diagrams, 7 Graphs

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Academic Journal

Proof of stability of an RSV Controlled Human Infection Model challenge agent.

  • Authors : Verstraelen S; Environmental Intelligence Unit, Flemish Institute for Technological Research (VITO), Industriezone Vlasmeer 7, Mol, 2400, Belgium. .; Roymans D

Subjects: Respiratory Syncytial Virus, Human*/Respiratory Syncytial Virus, Human*/Respiratory Syncytial Virus, Human*/physiology ; Respiratory Syncytial Virus, Human*/Respiratory Syncytial Virus, Human*/Respiratory Syncytial Virus, Human*/genetics ; Respiratory Syncytial Virus Infections*/Respiratory Syncytial Virus Infections*/Respiratory Syncytial Virus Infections*/virology

  • Source: Virology journal [Virol J] 2024 May 15; Vol. 21 (1), pp. 112. Date of Electronic Publication: 2024 May 15.Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X

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Academic Journal

JNJ-7184, a respiratory syncytial virus inhibitor targeting the connector domain of the viral polymerase.

  • Authors : Bonneux B; Laboratory for Microbiology, Parasitology and Hygiene, University of Antwerp, Universiteitsbaan 1, 2610 Wilrijk, Belgium; Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340 Beerse, Belgium.

Subjects: Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/chemistry ; Respiratory Syncytial Virus Infections*/Respiratory Syncytial Virus Infections*/Respiratory Syncytial Virus Infections*/drug therapy

  • Source: Antiviral research [Antiviral Res] 2024 Jul; Vol. 227, pp. 105907. Date of Electronic Publication: 2024 May 19.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor.

  • Authors : Yu X; Johnson & Johnson Innovative Medicine, Spring House, Pennsylvania, PA, 19477, USA. .; Abeywickrema P

Subjects: Respiratory Syncytial Virus, Human*; RNA-Dependent RNA Polymerase/RNA-Dependent RNA Polymerase/RNA-Dependent RNA Polymerase/chemistry ; Protein Binding

  • Source: Communications biology [Commun Biol] 2023 Oct 21; Vol. 6 (1), pp. 1074. Date of Electronic Publication: 2023 Oct 21.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation.

Subjects: DNA Methylation*; Methyltransferases/Methyltransferases/Methyltransferases/*metabolism ; RNA Caps/RNA Caps/RNA Caps/*metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2021 May 06; Vol. 17 (5), pp. e1009562. Date of Electronic Publication: 2021 May 06 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1 H -indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2 H -imidazo[4,5- c ]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus.

  • Authors : Vendeville S; Janssen Pharmaceutica NV, Janssen Pharmaceutical Companies of Johnson & Johnson, Turnhoutseweg 30, 2340 Beerse, Belgium.; Tahri A

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*chemistry ; Drug Discovery/Drug Discovery/Drug Discovery/*methods ; Imidazolidines/Imidazolidines/Imidazolidines/*chemistry

  • Source: Journal of medicinal chemistry [J Med Chem] 2020 Aug 13; Vol. 63 (15), pp. 8046-8058. Date of Electronic Publication: 2020 Jun 15.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Development of a Stable Respiratory Syncytial Virus Pre-Fusion Protein Powder Suitable for a Core-Shell Implant with a Delayed Release in Mice: A Proof of Concept Study.

  • Authors : Beugeling M; Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands. .; Amssoms K

  • Source: Pharmaceutics [Pharmaceutics] 2019 Oct 03; Vol. 11 (10). Date of Electronic Publication: 2019 Oct 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print)

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