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Academic Journal

Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase.

  • Authors : Faulkner RA; Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9046.; Yang Y

Subjects: Sterols*/Sterols*/Sterols*/metabolism ; Phytosterols*; Endoplasmic Reticulum-Associated Degradation

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Feb 13; Vol. 121 (7), pp. e2318822121. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Novel sterol binding domains in bacteria.

  • Authors : Zhai L; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, United States.; Bonds AC

Subjects: Sterols*/Sterols*/Sterols*/metabolism ; Phytosterols*/Phytosterols*/Phytosterols*/metabolism; Bacteria/Bacteria/Bacteria/genetics

  • Source: ELife [Elife] 2024 Feb 08; Vol. 12. Date of Electronic Publication: 2024 Feb 08.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Conformational changes in the Niemann-Pick type C1 protein NCR1 drive sterol translocation.

  • Authors : Frain KM; Department of Molecular Biology and Genetics, Aarhus University, Aarhus C 8000, Denmark.; Dedic E

Subjects: Sterols*/Sterols*/Sterols*/metabolism ; Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/genetics ; Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/metabolism

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Apr 09; Vol. 121 (15), pp. e2315575121. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

7-Dehydrocholesterol: A sterol shield against an iron sword.

  • Authors : Cui S; College of Biomedicine and Health, Huazhong Agricultural University, Wuhan, Hubei 430070, China; College of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China

Subjects: Sterols* ; Iron*; Dehydrocholesterols/Dehydrocholesterols/Dehydrocholesterols/metabolism

  • Source: Molecular cell [Mol Cell] 2024 Apr 04; Vol. 84 (7), pp. 1183-1185.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164

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Academic Journal

B-ring sterols to the rescue.

  • Authors : Senft D; Nature Reviews Cancer, . .

Subjects: Sterols*; Humans ; Structure-Activity Relationship

  • Source: Nature reviews. Cancer [Nat Rev Cancer] 2024 Apr; Vol. 24 (4), pp. 231.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124168 Publication Model: Print Cited Medium: Internet ISSN: 1474-1768

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Academic Journal

Oxygen-18 Labeling Reveals a Mixed Fe-O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α-Demethylation.

  • Authors : McCarty KD; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA.; Tateishi Y

Subjects: Sterols* ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism ; Formates*

  • Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Feb 26; Vol. 63 (9), pp. e202317711. Date of Electronic Publication: 2024 Jan 24.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

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Academic Journal

Druggable Sterol Metabolizing Enzymes in Infectious Diseases: Cell Targets to Therapeutic Leads.

  • Authors : Nes WD; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.; Chaudhuri M

Subjects: Sterols*/Sterols*/Sterols*/chemistry ; Communicable Diseases*; Humans

  • Source: Biomolecules [Biomolecules] 2024 Feb 20; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Truncated derivatives of amphidinol 3 reveal the functional role of polyol chain in sterol-recognition and pore formation.

  • Authors : Matsumori N; Department of Chemistry, Graduate School of Science, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan. Electronic address: .; Hieda M

Subjects: Sterols*/Sterols*/Sterols*/pharmacology ; Sterols*/Sterols*/Sterols*/chemistry ; Amphidinols*

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Jan 15; Vol. 98, pp. 129594. Date of Electronic Publication: 2023 Dec 15.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Sterols in Inflammatory Diseases: Implications and Clinical Utility.

  • Authors : Yalcinkaya A; Department of Medical Biochemistry, Faculty of Medicine, Hacettepe University, Ankara, Turkey.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.

Subjects: Sterols*/Sterols*/Sterols*/metabolism ; Phytosterols*/Phytosterols*/Phytosterols*/chemistry ; Phytosterols*/Phytosterols*/Phytosterols*/metabolism

  • Source: Advances in experimental medicine and biology [Adv Exp Med Biol] 2024; Vol. 1440, pp. 261-275.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Fully activated structure of the sterol-bound Smoothened GPCR-Gi protein complex.

  • Authors : Vo AP; Materials and Process Simulation Center, Division of Chemistry & Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.; Kim SK

Subjects: Sterols*/Sterols*/Sterols*/metabolism ; Hedgehog Proteins*/Hedgehog Proteins*/Hedgehog Proteins*/metabolism; Humans

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Dec 05; Vol. 120 (49), pp. e2300919120. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  25,795 results for ""STEROLS""