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Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia

• Authors : Taub, JW; Matherly, LH; Stout, ML

• Source: Blood; April 1996, Vol. 87 Issue: 8 p3395-3403, 9p

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Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric acute myeloid leukemia.

• Authors : Xie C; Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, 110 E. Warren Avenue, Detroit, MI 48201, USA.; Edwards H

Subjects: Cytarabine/Cytarabine/Cytarabine/*pharmacology ; Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/*drug therapy ; Valproic Acid/Valproic Acid/Valproic Acid/*pharmacology

• Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2010 Nov 15; Vol. 16 (22), pp. 5499-510. Date of Electronic Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia.

• Authors : Ge Y; Experimental and Clinical Therapeutics Program, Barbara Ann Karmanos Cancer Institute of Environmental Sciences, Wayne State University, Detroit, MI 48201, USA.; Dombkowski AA

Subjects: Down Syndrome/Down Syndrome/Down Syndrome/*genetics ; GATA1 Transcription Factor/GATA1 Transcription Factor/GATA1 Transcription Factor/*genetics ; Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/Leukemia, Megakaryoblastic, Acute/*drug therapy

• Source: Blood [Blood] 2006 Feb 15; Vol. 107 (4), pp. 1570-81. Date of Electronic Publication: 2005 Oct 25.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0006-4971

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Role of USF1 in the differential expression of the human deoxycytidine kinase gene in acute myeloid leukemia.

• Authors : Ge Y; Jensen TL; Tatman DA

Subjects: DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics ; Deoxycytidine Kinase/Deoxycytidine Kinase/Deoxycytidine Kinase/*genetics ; Leukemia, Myeloid/Leukemia, Myeloid/Leukemia, Myeloid/*genetics

• Source: Leukemia [Leukemia] 2005 Apr; Vol. 19 (4), pp. 677-9.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print Cited Medium: Print

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GATA1, cytidine deaminase, and the high cure rate of Down syndrome children with acute megakaryocytic leukemia.

• Authors : Ge Y; Experimental and Clinical Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA.; Stout ML

Subjects: Cytidine Deaminase/Cytidine Deaminase/Cytidine Deaminase/*metabolism ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; Down Syndrome/Down Syndrome/Down Syndrome/*complications

• Source: Journal of the National Cancer Institute [J Natl Cancer Inst] 2005 Feb 02; Vol. 97 (3), pp. 226-31.Publisher: Oxford University Press Country of Publication: United States NLM ID: 7503089 Publication Model: Print Cited Medium: Internet ISSN:

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The role of cytidine deaminase and GATA1 mutations in the increased cytosine arabinoside sensitivity of Down syndrome myeloblasts and leukemia cell lines.

• Authors : Ge Y; Experimental and Clinical Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, Michigan, USA.; Jensen TL

Subjects: Cytarabine/Cytarabine/Cytarabine/*toxicity ; Cytosine Deaminase/Cytosine Deaminase/Cytosine Deaminase/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics

• Source: Cancer research [Cancer Res] 2004 Jan 15; Vol. 64 (2), pp. 728-35.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Print

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Cystathionine-beta-synthase cDNA transfection alters the sensitivity and metabolism of 1-beta-D-arabinofuranosylcytosine in CCRF-CEM leukemia cells in vitro and in vivo: a model of leukemia in Down syndrome.

• Authors : Taub JW; Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit 48201, USA.; Huang X

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology ; Cystathionine beta-Synthase/Cystathionine beta-Synthase/Cystathionine beta-Synthase/*genetics ; Cytarabine/Cytarabine/Cytarabine/*pharmacology

• Source: Cancer research [Cancer Res] 2000 Nov 15; Vol. 60 (22), pp. 6421-6.Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Print

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Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin.

• Authors : Taub JW; Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI, USA.; Huang X

Subjects: Chromosomes, Human, Pair 21*; Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/*pharmacology ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology

• Source: Blood [Blood] 1999 Aug 15; Vol. 94 (4), pp. 1393-400.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Print ISSN: 0006-4971 (Print)

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Myeloblasts from Down syndrome children with acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin.

• Authors : Taub JW; Stout ML; Buck SA

Subjects: Cytarabine/Cytarabine/Cytarabine/*therapeutic use ; Daunorubicin/Daunorubicin/Daunorubicin/*therapeutic use ; Down Syndrome/Down Syndrome/Down Syndrome/*pathology

• Source: Leukemia [Leukemia] 1997 Sep; Vol. 11 (9), pp. 1594-5.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print Cited Medium: Print

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Alkylsulphonic acid ion pairing with radial compression columns for determining plasma or cerebrospinal fluid 1-beta-D-arabinofuranosylcytosine in pediatric pharmacokinetic analysis.

• Authors : Stout ML; Department of Pediatrics, Wayne State University, Detroit, MI.; Ravindranath Y

Subjects: Chromatography, High Pressure Liquid/Chromatography, High Pressure Liquid/Chromatography, High Pressure Liquid/*methods ; Cytarabine/Cytarabine/Cytarabine/*analysis ; Sulfonic Acids/Sulfonic Acids/Sulfonic Acids/*chemistry

• Source: Journal of chromatography. A [J Chromatogr A] 1995 Feb 10; Vol. 692 (1-2), pp. 59-66.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print Cited Medium: Print ISSN: 0021-9673 (Print)

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