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Academic Journal

Synthetic transcription factor engineering for cell and gene therapy.

  • Authors : Bhatt B; Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, and Baylor College of Medicine, Houston, TX, USA.; García-Díaz P

Subjects: Transcription Factors*/Transcription Factors*/Transcription Factors*/genetics ; Transcription Factors*/Transcription Factors*/Transcription Factors*/metabolism ; Gene Expression Regulation*

  • Source: Trends in biotechnology [Trends Biotechnol] 2024 Apr; Vol. 42 (4), pp. 449-463. Date of Electronic Publication: 2023 Oct 19.Publisher: Elsevier Science Publishers Country of Publication: England NLM ID: 8310903 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A heat-inducible expression system for external control of gene expression in plastids.

  • Authors : Xu W; State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan, China.; Li S

Subjects: Hot Temperature* ; Plastids*/Plastids*/Plastids*/genetics ; Plastids*/Plastids*/Plastids*/metabolism

  • Source: Plant biotechnology journal [Plant Biotechnol J] 2024 Apr; Vol. 22 (4), pp. 960-969. Date of Electronic Publication: 2023 Dec 07.Publisher: Wiley on behalf of the Society for Experimental Biology, Association of Applied Biologists Country of Publication: England NLM ID: 101201889 Publication

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Academic Journal

Improving CRISPR-Cas9 directed faithful transgene integration outcomes by reducing unwanted random DNA integration.

  • Authors : Hermantara R; School of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. .; Department of Biomedicine, School of Life Sciences, Indonesia International Institute for Life Sciences, Jakarta, Indonesia. .

Subjects: CRISPR-Cas Systems* ; Gene Editing*/Gene Editing*/Gene Editing*/methods; Humans

  • Source: Journal of biomedical science [J Biomed Sci] 2024 Mar 26; Vol. 31 (1), pp. 32. Date of Electronic Publication: 2024 Mar 26.Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127

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Academic Journal

Transgene-Free Cynomolgus Monkey iPSCs Generated under Chemically Defined Conditions.

  • Authors : Tereshchenko Y; Research Platform Degenerative Diseases, German Primate Center-Leibniz Institute for Primate Research, Kellnerweg 4, 37077 Göttingen, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Göttingen, 37075 Göttingen, Germany.

Subjects: Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/metabolism; Animals ; Humans

  • Source: Cells [Cells] 2024 Mar 21; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Intrathecal Gene Therapy for Giant Axonal Neuropathy.

Subjects: Genetic Therapy*/Genetic Therapy*/Genetic Therapy*/adverse effects ; Genetic Therapy*/Genetic Therapy*/Genetic Therapy*/methods ; Giant Axonal Neuropathy*/Giant Axonal Neuropathy*/Giant Axonal Neuropathy*/genetics

  • Source: The New England journal of medicine [N Engl J Med] 2024 Mar 21; Vol. 390 (12), pp. 1092-1104.Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Multiplexed CRISPR-Cas9 protocol for large transgene integration into the Schistosoma mansoni genome.

  • Authors : Ittiprasert W; Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, George Washington University, Washington, DC 20037, USA. Electronic address: .; Moescheid MM

Subjects: CRISPR-Cas Systems*/CRISPR-Cas Systems*/CRISPR-Cas Systems*/genetics ; Schistosoma mansoni*/Schistosoma mansoni*/Schistosoma mansoni*/genetics; Animals

  • Source: STAR protocols [STAR Protoc] 2024 Mar 15; Vol. 5 (1), pp. 102886. Date of Electronic Publication: 2024 Feb 13.Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

In planta transformation in wheat: an improved protocol to develop wheat transformants.

  • Authors : Kumar S; ICAR-National Institute for Plant Biotechnology, Pusa Campus, New Delhi, 110012, India.; Vishwakarma H

Subjects: Triticum*/Triticum*/Triticum*/genetics ; Agrobacterium tumefaciens*/Agrobacterium tumefaciens*/Agrobacterium tumefaciens*/genetics; Plants, Genetically Modified/Plants, Genetically Modified/Plants, Genetically Modified/genetics

  • Source: Molecular biology reports [Mol Biol Rep] 2024 Mar 09; Vol. 51 (1), pp. 407. Date of Electronic Publication: 2024 Mar 09.Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978

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Academic Journal

Calcineurin contributes to RNAi-mediated transgene silencing and small interfering RNA production in the human fungal pathogen Cryptococcus neoformans.

  • Authors : Yadav V; Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.; Mohan R

Subjects: Cryptococcus neoformans*/Cryptococcus neoformans*/Cryptococcus neoformans*/metabolism ; Cryptococcosis*/Cryptococcosis*/Cryptococcosis*/microbiology; Humans

  • Source: Genetics [Genetics] 2024 Mar 06; Vol. 226 (3).Publisher: Oxford University Press Country of Publication: United States NLM ID: 0374636 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Optimization strategies and advances in the research and development of AAV-based gene therapy to deliver large transgenes.

  • Authors : Kolesnik VV; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov University, Moscow, Russia.; Nurtdinov RF

Subjects: Dependovirus*/Dependovirus*/Dependovirus*/genetics ; Dependovirus*/Dependovirus*/Dependovirus*/metabolism ; Genetic Therapy*

  • Source: Clinical and translational medicine [Clin Transl Med] 2024 Mar; Vol. 14 (3), pp. e1607.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Academic Journal

Permanent transduction of retinal ganglion cells by rAAV2-retro.

  • Authors : Zheng YJ; Program in Neuroscience, Department of Ophthalmology University of California, San Francisco, San Francisco, CA, 94143, USA.; Dilbeck MD

Subjects: Retinal Ganglion Cells* ; Genetic Vectors*; Rats

  • Source: Experimental eye research [Exp Eye Res] 2024 Mar; Vol. 240, pp. 109793. Date of Electronic Publication: 2024 Jan 19.Publisher: Academic Press Country of Publication: England NLM ID: 0370707 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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