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Academic Journal

Involvement of BCR::ABL1 in laminin adhesion of Philadelphia chromosome-positive  acute lymphoblastic leukemia through upregulation of integrin α6.

  • Authors : Takahashi K; Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Chuo, Japan.; Nguyen TTT

Subjects: Integrin alpha6*/Integrin alpha6*/Integrin alpha6*/genetics ; Laminin*/Laminin*/Laminin*/metabolism ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*/Precursor Cell Lymphoblastic Leukemia-Lymphoma*/Precursor Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy

  • Source: Cancer reports (Hoboken, N.J.) [Cancer Rep (Hoboken)] 2024 Apr; Vol. 7 (4), pp. e2034.Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101747728 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

CHIP suppresses the proliferation and migration of A549 cells by mediating the ubiquitination of eIF2α and upregulation of tumor suppressor RBM5.

  • Authors : Jin B; Engineering Research Center of Cell and Therapeutic Antibody, Ministry of Education, and School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, China.; Wang M

Subjects: Eukaryotic Initiation Factor-2*/Eukaryotic Initiation Factor-2*/Eukaryotic Initiation Factor-2*/genetics ; Eukaryotic Initiation Factor-2*/Eukaryotic Initiation Factor-2*/Eukaryotic Initiation Factor-2*/metabolism ; Genes, Tumor Suppressor*

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Mar; Vol. 300 (3), pp. 105673. Date of Electronic Publication: 2024 Jan 23.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Neuroprotective effect of isovaleraldehyde accompanied with upregulation of BDNF and CREB phosphorylation via the PKA pathway.

  • Authors : Shimada Y; Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 744 Motooka, Nishi-Ku, Fukuoka, 819-0395, Japan.; Kumazoe M

Subjects: Neuroprotective Agents*/Neuroprotective Agents*/Neuroprotective Agents*/pharmacology ; Aldehydes*/Aldehydes*/Aldehydes*/pharmacology ; Up-Regulation*/Up-Regulation*/Up-Regulation*/drug effects

  • Source: Journal of natural medicines [J Nat Med] 2024 Jan; Vol. 78 (1), pp. 208-215. Date of Electronic Publication: 2023 Dec 08.Publisher: Springer Country of Publication: Japan NLM ID: 101518405 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1861-0293

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Academic Journal

A Combination of Conformation-Specific RAF Inhibitors Overcome Drug Resistance Brought about by RAF Overexpression.

  • Authors : Imoto H; Systems Biology Ireland, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.; Rauch N

Subjects: Up-Regulation*; Computer Simulation ; Down-Regulation

  • Source: Biomolecules [Biomolecules] 2023 Aug 02; Vol. 13 (8). Date of Electronic Publication: 2023 Aug 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy.

  • Authors : Liu YC; From the Department of Pathology, Brigham and Women's Hospital (Y.-C.L., C. Gao, Jun Liu, J.Y., L. Chai), Harvard Stem Cell Institute, Harvard Medical School (A.I.J., M.A.B., D.G.T.), and the Department of Medical Oncology, Dana-Farber Cancer Institute (R.P.) - all in Boston; the Division of Hematology, Department of Medicine, Taipei Veterans General Hospital (Y.-C.L.), and the Faculty of Medicine and the Program in Molecular Medicine, Institute of Biopharmaceutical Sciences, School of Life Science, National Yang Ming Chiao Tung University (Y.-C.L., J.-H.L.) - both in Taipei, Taiwan

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Demethylation*/Demethylation*/Demethylation*/drug effects

  • Source: The New England journal of medicine [N Engl J Med] 2022 May 26; Vol. 386 (21), pp. 1998-2010.Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Up-regulation of long noncoding RNA MBNL1-AS1 suppresses breast cancer progression by modulating miR-423-5p/CREBZF axis.

  • Authors : Fang J; Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China.; Jiang G

Subjects: Gene Expression Regulation, Neoplastic* ; Signal Transduction* ; Up-Regulation*

  • Source: Bioengineered [Bioengineered] 2022 Feb; Vol. 13 (2), pp. 3707-3723.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101581063 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

miR‑27a‑3p upregulation by p65 facilitates cervical tumorigenesis by increasing TAB3 expression and is involved in the positive feedback loop of NF‑κB signaling.

  • Authors : Li M; Department of Pathogen Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, P.R. China.; Gao Z

Subjects: Up-Regulation* ; Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

  • Source: Oncology reports [Oncol Rep] 2023 Jul; Vol. 50 (1). Date of Electronic Publication: 2023 May 19.Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9422756 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Wnt5A and TGFβ1 Converges through YAP1 Activity and Integrin Alpha v Up-Regulation Promoting Epithelial to Mesenchymal Transition in Ovarian Cancer Cells and Mesothelial Cell Activation.

  • Authors : Dehghani-Ghobadi Z; Developmental Biology Laboratory, Department of Animal Biology, School of Biology, College of Science, University of Tehran, Tehran 1417614411, Iran.; Sheikh Hasani S

Subjects: Up-Regulation*/Up-Regulation*/Up-Regulation*/genetics; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*genetics ; Epithelium/Epithelium/Epithelium/*pathology

  • Source: Cells [Cells] 2022 Jan 11; Vol. 11 (2). Date of Electronic Publication: 2022 Jan 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Up-regulation of SETD3 may contribute to post-stroke depression in rat through negatively regulating VEGF expression.

  • Authors : Feng Y; Department of Neurology, Jinan University, Guangzhou City 510000, China; Department of Neurology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Province 533000, China.

Subjects: Histone Methyltransferases*/Histone Methyltransferases*/Histone Methyltransferases*/metabolism ; Up-Regulation*; Depression/Depression/Depression/*etiology

  • Source: Behavioural brain research [Behav Brain Res] 2022 Jan 07; Vol. 416, pp. 113564. Date of Electronic Publication: 2021 Sep 07.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Simulated Microgravity Increases the Permeability of HUVEC Monolayer through Up-Regulation of Rap1GAP and Decreased Rap2 Activation.

  • Authors : Shi S; School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.; Li J

Subjects: Up-Regulation* ; Weightlessness Simulation*; GTPase-Activating Proteins/GTPase-Activating Proteins/GTPase-Activating Proteins/*genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 06; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  881,394 results for ""Up-Regulation""