[Generics: essentially similar, bioequivalent but not identical].

Les génériques: essentiellement similaires, bioéquivalents mais non identiques.

Publisher: Association des médecins anciens étudiants de l'Université libre de Bruxelles Country of Publication: Belgium NLM ID: 8003474 Publication Model: Print Cited Medium: Print ISSN: 0035-3639 (Print) Linking ISSN: 00353639 NLM ISO Abbreviation: Rev Med Brux Subsets: MEDLINE

Original Publication: [Bruxelles] Association des médecins anciens étudiants de l'Université libre de Bruxelles [1945]-

Drugs, Generic/*pharmacokinetics ; Drugs, Generic/*standards; Belgium ; Chemistry, Pharmaceutical ; Cost Savings ; Drug Costs ; Drug Prescriptions/economics ; Drug Prescriptions/standards ; Drug and Narcotic Control ; Drugs, Generic/chemistry ; Drugs, Generic/economics ; Drugs, Generic/supply & distribution ; Health Policy ; Humans ; Marketing of Health Services ; Therapeutic Equivalency ; Treatment Outcome

The using of generic forms (GF) is presented as a potential source of budgetary "saving of money" in the field of pharmaceutical expenses. Not frequently prescribed in Belgium, they win a new interest thanks to the recent making use of the "reference repayment". Sale's authorization of GF is controlled by european rules, but some questions about their identity to original medications remain. Do similarities based only upon qualitative and quantitative composition in active molecules, pharmaceutical forms and biodisponibility give us all requested guarantees? Several cases of discordances can appear: the major elements of non conformity are the nature of excipients, notice's contents and the value of biodisponibility studies. However, in term of economy, in the drug market, development of GF appears to constitute an unavoidable phenomenon.

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0 (Drugs, Generic)

Date Created: 20020129 Date Completed: 20020301 Latest Revision: 20081121

20240513

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