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Academic Journal

Genome organization around nuclear speckles drives mRNA splicing efficiency.

  • Authors : Bhat P; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

Subjects: Genome*/Genome*/Genome*/genetics ; Nuclear Speckles*/Nuclear Speckles*/Nuclear Speckles*/genetics ; Nuclear Speckles*/Nuclear Speckles*/Nuclear Speckles*/metabolism

  • Source: Nature [Nature] 2024 May; Vol. 629 (8014), pp. 1165-1173. Date of Electronic Publication: 2024 May 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Assessing the Impact of Novel BRCA1 Exon 11 Variants on Pre-mRNA Splicing.

  • Authors : Elshwekh H; International Centre for Genetic Engineering and Biotechnology, Padriciano 99, 34149 Trieste, Italy.; Department of Genetic Engineering, Libyan Biotechnology Research Center, Tripoli P.O. Box 30313, Libya.

Subjects: Exons*/Exons*/Exons*/genetics ; BRCA1 Protein*/BRCA1 Protein*/BRCA1 Protein*/genetics ; BRCA1 Protein*/BRCA1 Protein*/BRCA1 Protein*/metabolism

  • Source: Cells [Cells] 2024 May 11; Vol. 13 (10). Date of Electronic Publication: 2024 May 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

An interpretable model of pre-mRNA splicing for animal and plant genes.

  • Authors : McCue K; Computational and Systems Biology PhD Program, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.

Subjects: RNA Precursors*/RNA Precursors*/RNA Precursors*/genetics ; RNA Precursors*/RNA Precursors*/RNA Precursors*/metabolism ; RNA Splicing*

  • Source: Science advances [Sci Adv] 2024 May 10; Vol. 10 (19), pp. eadn1547. Date of Electronic Publication: 2024 May 08.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic

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Academic Journal

Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter.

  • Authors : Ni Z; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada.; Ahmed N

Subjects: CRISPR-Cas Systems* ; Genes, Reporter* ; mRNA Cleavage and Polyadenylation Factors*/mRNA Cleavage and Polyadenylation Factors*/mRNA Cleavage and Polyadenylation Factors*/metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 May 08; Vol. 52 (8), pp. 4483-4501.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

THUMPD2 catalyzes the N2-methylation of U6 snRNA of the spliceosome catalytic center and regulates pre-mRNA splicing and retinal degeneration.

  • Authors : Yang WQ; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.; Ge JY

Subjects: Retinal Degeneration*/Retinal Degeneration*/Retinal Degeneration*/metabolism ; RNA Precursors*/RNA Precursors*/RNA Precursors*/genetics ; RNA Precursors*/RNA Precursors*/RNA Precursors*/metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2024 Apr 12; Vol. 52 (6), pp. 3291-3309.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Post-transcriptional splicing can occur in a slow-moving zone around the gene.

  • Authors : Coté A; Department of Bioengineering, University of Pennsylvania, Philadelphia, United States.; O'Farrell A

Subjects: RNA Precursors*/RNA Precursors*/RNA Precursors*/genetics ; RNA Precursors*/RNA Precursors*/RNA Precursors*/metabolism ; Transcription, Genetic*

  • Source: ELife [Elife] 2024 Apr 05; Vol. 12. Date of Electronic Publication: 2024 Apr 05.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

MAPP unravels frequent co-regulation of splicing and polyadenylation by RNA-binding proteins and their dysregulation in cancer.

  • Authors : Bak M; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland.; Biozentrum, University of Basel, 4056, Basel, Switzerland.

Subjects: RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/metabolism ; RNA-Binding Proteins*/RNA-Binding Proteins*/RNA-Binding Proteins*/genetics ; Polyadenylation*

  • Source: Nature communications [Nat Commun] 2024 May 15; Vol. 15 (1), pp. 4110. Date of Electronic Publication: 2024 May 15.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Alternative pre-mRNA splicing in stem cell function and therapeutic potential: A critical review of current evidence.

  • Authors : Cui L; Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, 510280, Guangdong, China. Electronic address: .; Zheng Y

Subjects: Alternative Splicing* ; RNA Precursors*/RNA Precursors*/RNA Precursors*/genetics ; RNA Precursors*/RNA Precursors*/RNA Precursors*/metabolism

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2024 May; Vol. 268 (Pt 1), pp. 131781. Date of Electronic Publication: 2024 Apr 22.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Transcription and splicing variations of SR genes accompany with genome-wide accumulation of long-introns in pine.

  • Authors : Chen S; College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.; Zhang Y

Subjects: RNA Precursors*/RNA Precursors*/RNA Precursors*/genetics ; Arabidopsis*/Arabidopsis*/Arabidopsis*/genetics; Introns/Introns/Introns/genetics

  • Source: Plant science : an international journal of experimental plant biology [Plant Sci] 2024 May; Vol. 342, pp. 112056. Date of Electronic Publication: 2024 Mar 02.Publisher: Elsevier Ireland Country of Publication: Ireland NLM ID: 9882015 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RNA Pol II-dependent transcription efficiency fine-tunes A-to-I editing levels.

  • Authors : Szabo B; Department of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, A-1090 Vienna, Austria.; Mandl TC

Subjects: RNA Polymerase II*/RNA Polymerase II*/RNA Polymerase II*/genetics ; RNA Precursors*/RNA Precursors*/RNA Precursors*/genetics ; RNA Precursors*/RNA Precursors*/RNA Precursors*/metabolism

  • Source: Genome research [Genome Res] 2024 Mar 20; Vol. 34 (2), pp. 231-242. Date of Electronic Publication: 2024 Mar 20.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9518021 Publication Model: Electronic Cited Medium:

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  • 1-10 of  17,300 results for ""RNA Precursors""