Presumed moxidectin toxicosis in three foals.

Publisher: American Veterinary Medical Association Country of Publication: United States NLM ID: 7503067 Publication Model: Print Cited Medium: Print ISSN: 0003-1488 (Print) Linking ISSN: 00031488 NLM ISO Abbreviation: J Am Vet Med Assoc Subsets: MEDLINE

Publication: Mar. 1975- : Schaumburg, Ill. : American Veterinary Medical Association
Original Publication: Ithaca, N.Y. : [American Veterinary Medical Association, 1915]-

Anthelmintics/*poisoning ; Coma/*veterinary ; Horse Diseases/*chemically induced; Administration, Oral ; Animals ; Animals, Newborn ; Anthelmintics/administration & dosage ; Anti-Bacterial Agents ; Coma/chemically induced ; Drug Overdose/veterinary ; Fatal Outcome ; Female ; Gels ; Horses ; Macrolides/administration & dosage ; Macrolides/poisoning ; Male ; Nonprescription Drugs/administration & dosage ; Nonprescription Drugs/poisoning

Outcome and complications associated with administration of moxidectin gel to 3 foals < 4 months old are described. Two foals became comatose but survived following supportive treatment. One foal died following loss of consciousness associated with moxidectin administration. Risk of moxidectin overdose exists, because horse owners often fail to read or comprehend the package insert instructions pertaining to use of the syringe-locking mechanism. In addition, moxidectin should not be administered to foals < 4 months old, because it is likely that treated foals will become comatose.

0 (Anthelmintics)
0 (Anti-Bacterial Agents)
0 (Gels)
0 (Macrolides)
0 (Nonprescription Drugs)
NGU5H31YO9 (moxidectin)

Date Created: 19990324 Date Completed: 19990510 Latest Revision: 20191210

20240513

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