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مقايسه آزمايشگاهي اثر ضدكانديدايي عصاره هيدرو الكلي دارچين و مازو با نيستاتين در درمان دنجر استئوماتيت. (Arabic)
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- Author(s): فريده مهدوي; عليرضا اميرخاني; فاطمه اولياء
- Source:
Journal of Research in Dental Sciences; 2020, Vol. 17 Issue 3, p192-200, 9p- Subject Terms:
- Source:
- Additional Information
- Alternate Title: In vitro comparison of Anti-Candidal Activity of cinnamon and Querques infectoria hydroalcholic extracts with nystatin in treatment of denture stomatitis. (English)
- Abstract: Background and Aim: Candida albicans play the main role in the onset, preservation and progression of denture stomatitis. Therefore, the present study was conducted with the aim of comparing the anti candidal effect of cinnamon and Querques infectoria extracts with nystatin for treatment of denture stomatitis. Materials and methods: In this experimental study, 43 patients with clinical diagnosis of denture stomatitis were selected and maxillary dentures were taken for 24 hours. Dentures randomly were divided into three groups of 14 tests and one denture was considered as a negative control group for immersion in distilled water. From the tissue surface, all dentures were sampled with swab and the samples were transferred to the laboratory after transfer to the culture medium and the colony count (CFU / mm2) was measured. Then, each of the 14 denture groups were immersed in a hydroalcoholic solution of cinnamon (70%), a hydroalcoholic solution of Querques infectoria (70%) and nystatin suspension for 24 hours. After 24 hours, repeat sampling and colony count was measured and then the colony count before and after immersion was compared. Data was analyzed using SPSS17 statistical software, Chi-square, Fisher exact tests and ANOVA. Results: There was no significant difference between the three groups obtained colony counts of Candida albicans from dentures (P-value = 0.01). Conclusion: Both herbal extracts could be effective on treatment of denture stomatitis. It should be more evaluated in future studies. [ABSTRACT FROM AUTHOR]
- Abstract: كانديدا آلبيكنس نقش اصلي را در شروع، حفظ و پيشرفت دنچر استوماتيت بازي مي كنند. لذا مطالعه حاضر با هدف مقايسه آزمايشگاهي اثر ضد كانديدايي عصاره هيدرو الكلي گياهان دارچين و مازو با نيستاتين در درمان دنچر استوماتيت انجام شد. مواد و روش ها: دراين مطالعه تجربي آزمايشگاهي،43 بيمار با تشخيص باليني دنچر استوماتيت انتخاب شده و دنچر هاي فك بالاي بيماران به مدت 24 ساعت از آنها گرفته شد. دنچرها به طور تصادفي به سه گروه آزمايش 14 تايي تقسيم شده و يك دنچر به عنوان گروه كنترل منفي براي غوطه ورسازي در آب مقطر در نظرگرفته شد. از سطح بافتي تمام دنچر ها با سوآب نمونه گيري شده و نمونه ها پس از انتقال به محيط كشت به آزمايشگاه منتقل شدند و تعداد كلوني(mm2/cfu)اندازه گيري شد. سپس هركدام از گروه هاي 14تايي دنچر در محلول هيدروالكلي دارچين(70 ،(%محلول هيدروالكلي مازو (70 (%و سوسپانسيون نيستاتين به مدت 24 ساعت غوطه ور گرديدند. پس از 24ساعت نمونه گيري تكرار و تعداد كلونيها اندازه گيري شد و سپس ميزان كلوني هاي قبل و بعد از غوطه ور شدن مقايسه شدند. داده ها با استفاده از نرم افزار آماري SPSS17 و آزمون هاي آماري square-Chi و Fisher exactوANOVA تجزيه و تحليل شدند. يافته ها: تفاوت معني داري در سه گروه مورد بررسي در ميزان كلوني به دست آمده كانديداآلبيكنس از دست دندان هاي مورد بررسي مشاهده نشد. (P=0/1) نتيجه گيري: عصاره هاي گياهان دارچين و مازو ميتوانند در درمان دنچر استوماتيت موثر باشند كه بايد در مطالعات بعدي مورد ارزيابي بيشتر قرار گيرد. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Journal of Research in Dental Sciences is the property of Islamic Azad University, Dental Branch and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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