[The importance of hemorheological examinations in experimental limb ischemia-reperfusion injuries].

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  • Additional Information
    • Transliterated Title:
      A haemorheologiai vizsgálatok jelentosége kísérletes végtagi ischaemiareperfusiós károsodások kapcsán.
    • Source:
      Publisher: Ifjúsági Lapkiadó Vállalat Country of Publication: Hungary NLM ID: 18420110R Publication Model: Print Cited Medium: Print ISSN: 0025-0295 (Print) Linking ISSN: 00250295 NLM ISO Abbreviation: Magy Seb Subsets: MEDLINE
    • Publication Information:
      Original Publication: Budapest, Ifjúsági Lapkiadó Vállalat.
    • Subject Terms:
      Erythrocyte Deformability* ; Hemorheology*; Extremities/*blood supply ; Reperfusion Injury/*physiopathology; Animals ; Disease Models, Animal ; Dogs ; Rats ; Time Factors
    • Abstract:
      Rheological properties of the blood are determined by several factors and if they change it may be diagnostic for many diseases. It is well-known that during ischemia and reperfusion different free-radical liberating pathways are inducted besides the local physical and metabolical changes. These processes may harm red blood cells by increasing their rigidity and impairing their deformability. In ischemia-reperfusion models measurements of erythrocyte deformability is important. Characteristic alterations were observed in both rat and dog hind limb ischemia-reperfusion with vascular clamping on femoral vessels for 1 or 3 hours. Erythrocyte deformability was significantly impaired on the postoperative 1st-3rd days. The acute limb ischemia-reperfusion experimental models seem suitable for further in vivo rheological studies.
    • Publication Date:
      Date Created: 20050716 Date Completed: 20050913 Latest Revision: 20061115
    • Publication Date:
      20231215
    • Accession Number:
      16018285