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Association between Iodized Salt Intake and Cognitive Function in Older Adults in China.
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- Author(s): Wu, M. N.; Liu, W. F.; Li, F. D.; Huang, Y. W.; Gu, X.; Zhai, Y. J.; Zhang, T.; Xu, L.; Lin, Junfen
- Source:
Journal of Nutrition, Health & Aging; Nov2023, Vol. 27 Issue 11, p1005-1011, 7p- Subject Terms:
COGNITION disorder risk factors; COGNITION disorders; CONFIDENCE intervals; MULTIVARIATE analysis; RISK assessment; NEUROPSYCHOLOGICAL tests; RESEARCH funding; QUESTIONNAIRES; DESCRIPTIVE statistics; DISEASE prevalence; LOGISTIC regression analysis; ODDS ratio; COGNITION in old age; DIETARY sodium; IODINE - Source:
- Additional Information
- Subject Terms:
- Abstract: Objectives: To investigate the association between iodized salt intake and cognitive function in older adults. Design: A cross-sectional study. Settings: Individuals from the Zhejiang Major Public Health Surveillance Program (ZPHS). Participants: Data of 10,217 participants (including 4,680 coastal residents and 5,537 inland residents) aged ≥ 60 years were analyzed. Measurements: Salt intake was evaluated using a questionnaire, and participants were stratified into the following three groups: iodized salt, non-iodized salt, and mixed salt. Cognitive function was assessed through the Mini-Mental State Examination and defined using education-specific cut-off points. Logistic regression models controlling for an extensive range of potential confounders were generated to examine the association between salt intake and cognitive function among all participants. Results: Data from 10,217 participants with a 16.1% prevalence of cognitive impairment were analyzed. Compared with non-iodized salt intake, consumption of iodized salt was inversely associated with cognitive impairment (odds ratio [OR], 0.410; 95% confidence interval [CI], 0.351–0.480; P < 0.001) in all participants after multivariable adjustment. An association between iodized salt intake and cognitive impairment was observed in coastal (OR, 0.441; 95% CI, 0.340–0.572; P < 0.001) and inland residents (OR, 0.569; 95% CI, 0.439–0.738; P < 0.001). Despite the insufficient sample size, the results for individuals consuming mixed salt suggested an inverse association between mixed salt intake and cognitive impairment among coastal residents (OR, 0.598; 95% CI, 0.405–0.885; P = 0.010) after multivariable adjustment. Conclusion: Our results indicate that iodized salt intake may reduce the risk of cognitive impairment in older adults living in coastal or inland areas, and the protective effect of iodized salt intake is greater in coastal areas than in inland areas. [ABSTRACT FROM AUTHOR]
- Abstract: Copyright of Journal of Nutrition, Health & Aging is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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