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Phone: (843) 887-3699
Folly Beach Library
9 a.m. - 1 p.m.
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Miss Jane's Building (Edisto Library Temporary Location)
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Main Library
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West Ashley Library
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John L. Dart Library
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St. Paul's/Hollywood Library
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Mt. Pleasant Library
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John's Island Library
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Wando Mount Pleasant Library
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Association Between Long-Term Exposure to Ambient Air Pollution and the Risk of Mild Cognitive Impairment in a Chinese Urban Area: A Case-Control Study.
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- Author(s): Xie, Xin-Yan; Huang, Lin-Ya; Cheng, Gui-Rong; Liu, Dan; Hu, Fei-Fei; Zhang, Jing-Jing; Han, Gang-Bin; Liu, Xiao-Chang; Wang, Jun-Yi; Zhou, Juan; Zeng, De-Yang; Liu, Jing; Nie, Qian-Qian; Song, Dan; Yu, Ya-Fu; Hu, Chen-Lu; Fu, Yi-Di; Li, Shi-Yue; Cai, Cheng; Cui, Yu-Yang
- Source:
Journal of Alzheimer's Disease; 2024, Vol. 98 Issue 3, p941-955, 15p- Subject Terms:
- Source:
- Additional Information
- Abstract: Background: As a prodromal stage of dementia, significant emphasis has been placed on the identification of modifiable risks of mild cognitive impairment (MCI). Research has indicated a correlation between exposure to air pollution and cognitive function in older adults. However, few studies have examined such an association among the MCI population inChina. Objective: We aimed to explore the association between air pollution exposure and MCI risk from the Hubei Memory and Aging Cohort Study. Methods: We measured four pollutants from 2015 to 2018, 3 years before the cognitive assessment of the participants. Logistic regression models were employed to calculate odds ratios (ORs) to assess the relationship between air pollutants and MCI risk. Results: Among 4,205 older participants, the adjusted ORs of MCI risk for the highest quartile of PM
2.5 , PM10 , O3 , and SO2 were 1.90 (1.39, 2.62), 1.77 (1.28, 2.47), 0.56 (0.42, 0.75), and 1.18 (0.87, 1.61) respectively, compared with the lowest quartile. Stratified analyses indicated that such associations were found in both males and females, but were more significant in older participants. Conclusions: Our findings are consistent with the growing evidence suggesting that air pollution increases the risk of mild cognitive decline, which has considerable guiding significance for early intervention of dementia in the older population. Further studies in other populations and broader geographical areas are warranted to validate these findings. [ABSTRACT FROM AUTHOR] - Abstract: Copyright of Journal of Alzheimer's Disease is the property of IOS Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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