Ensembl Genomes 2022: an expanding genome resource for non-vertebrates.

Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Publication: 1992- : Oxford : Oxford University Press
Original Publication: London, Information Retrieval ltd.

Databases, Genetic* ; Genomics* ; Internet* ; Software*; Animals ; Computational Biology ; Genome, Bacterial/genetics ; Genome, Fungal/genetics ; Genome, Plant/genetics ; Plants/classification ; Plants/genetics ; Vertebrates/classification ; Vertebrates/genetics

Ensembl Genomes (https://www.ensemblgenomes.org) provides access to non-vertebrate genomes and analysis complementing vertebrate resources developed by the Ensembl project (https://www.ensembl.org). The two resources collectively present genome annotation through a consistent set of interfaces spanning the tree of life presenting genome sequence, annotation, variation, transcriptomic data and comparative analysis. Here, we present our largest increase in plant, metazoan and fungal genomes since the project's inception creating one of the world's most comprehensive genomic resources and describe our efforts to reduce genome redundancy in our Bacteria portal. We detail our new efforts in gene annotation, our emerging support for pangenome analysis, our efforts to accelerate data dissemination through the Ensembl Rapid Release resource and our new AlphaFold visualization. Finally, we present details of our future plans including updates on our integration with Ensembl, and how we plan to improve our support for the microbial research community. Software and data are made available without restriction via our website, online tools platform and programmatic interfaces (available under an Apache 2.0 license). Data updates are synchronised with Ensembl's release cycle.
(© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.)

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75N93019C00077 United States AI NIAID NIH HHS; United Kingdom WT_ Wellcome Trust; U24 HG002223 United States HG NHGRI NIH HHS; 108749/Z/15/Z United Kingdom WT_ Wellcome Trust; MR/S000453/1 United Kingdom MRC_ Medical Research Council; 201535/Z/16/Z United Kingdom WT_ Wellcome Trust; BB/P024602/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; BB/P016855/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; BB/S02011X/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; BB/M028372/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; BB/P027849/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; BB/S020020/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; BB/T015691/1 United Kingdom BB_ Biotechnology and Biological Sciences Research Council; 222155/Z/20/Z United Kingdom WT_ Wellcome Trust

Date Created: 20211118 Date Completed: 20220223 Latest Revision: 20220223

20240513

PMC8728113

10.1093/nar/gkab1007

34791415