CHD-related/specific mortality of 3.17 million people in a transitioning region: trends, risk factors, and prevention.

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  • Additional Information
    • Source:
      Publisher: Springer Country of Publication: Germany NLM ID: 101132995 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1720-8319 (Electronic) Linking ISSN: 15940667 NLM ISO Abbreviation: Aging Clin Exp Res Subsets: MEDLINE
    • Publication Information:
      Publication: <2013-> : Berlin : Springer
      Original Publication: Milano, Italy : Editrice Kurtis, c2002-
    • Subject Terms:
      Aging* ; Coronary Disease*/epidemiology; Humans ; Aged ; China/epidemiology ; Risk Factors ; Mortality
    • Abstract:
      Background: Demographic shifts cause uncertain changes in the burden of coronary heart disease (CHD) in transitioning regions. We aimed to analyze the trends of CHD burden and its risk factors in Pudong, Shanghai, and explore prevention strategies for transitioning regions.
      Methods: We analyzed CHD-related and CHD-specific deaths in Pudong from 2005 to 2020, including the crude mortality rate (CMR), age-standardized mortality rate worldwide (ASMRW), years of life lost (YLL), and age-specific proportions. We also examined the impact of population aging on the burden of CHD. The Joinpoint Regression Program was used to analyze trends, and the decomposition method was used to evaluate the impact of demographics on the mortality rate.
      Results: Of the 86,171 CHD-related deaths, 52,152 (60.52%) were CHD-specific deaths. For both CHD-related and CHD-specific deaths, there was a significant increase in the CMR, ASMRW, and YLL rate, except in the 70-79-year age group, which exhibited a distinctive and statistically significant decline in these rates (all P < 0.05). There were steadily increasing trends in the rates caused by aging from 2005 to 2020, with average annual percent changes (AAPCs) of 42.59% and 41.43%, respectively (all P < 0.05).
      Conclusions: Our results indicate that the CHD burden in Pudong has been persistently increasing, but in the age group of 70-79 years, substantial declines were observed. The quality of primary healthcare services may be a critical point in addressing the overwhelming CHD burden.
      (© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
    • Grant Information:
      GWV-10.2-YQ43 Shanghai Public Health System Construction Three-year Action Plan Outstanding Youth Talent Training Program; 2019LJ15 Shanghai Municipal Program for Medical Leading Talents
    • Contributed Indexing:
      Keywords: Comorbidity; Coronary heart disease; Mortality; Primary health care; Trend analysis; Years of life lost
    • Publication Date:
      Date Created: 20231120 Date Completed: 20231216 Latest Revision: 20231216
    • Publication Date:
      20231217
    • Accession Number:
      10.1007/s40520-023-02618-1
    • Accession Number:
      37985650