Mindfulness-based intervention for hypertension patients with depression and/or anxiety in the community: a randomized controlled trial.

Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE

Original Publication: [London] : BioMed Central, 2006-

Mindfulness*/methods ; Hypertension*/therapy ; Hypertension*/psychology ; Depression*/therapy ; Depression*/psychology ; Anxiety*/therapy ; Anxiety*/psychology; Humans ; Male ; Female ; Middle Aged ; Aged ; Treatment Outcome ; Blood Pressure ; Self Efficacy ; Time Factors ; Mental Health

Objective: To evaluate mindfulness-based intervention for hypertension with depression and/or anxiety.
Methods: 10-week mindfulness-based intervention, including health education for hypertension, exclusively for the control group, was administered to the intervention group to assist sixty hypertension patients with depression/anxiety. Among them, the intervention group comprised 8 men and 22 women, with a mean age of 60.02 years and a mean duration of hypertension of 6.29 years. The control group consisted of 14 men and 16 women with a mean age of 57.68 years and a mean duration of hypertension of 6.32 years. The severity of depressive and/or anxiety symptoms was assessed using the 9-item Patient Health Questionnaire (PHQ-9) and the 7-item Generalized Anxiety Disorder scale (GAD-7), along with blood pressure (BP) measurements taken twice daily. The study utilized a self-made self-efficacy scale and awareness of physical and mental health to evaluate mental health and state.
Results: The depression PHQ-9 or GAD-7 scores reduced by 21.1% or 17.8% in the mindfulness-based intervention group, compared to the control (Z = -2.040, P = 0.041) post 10-week period, suggesting significant reduction in anxiety/stress. These results were consistent with a reduction in systolic BP of 12.24 mm Hg (t = 6.041, P = 0.000). The self-efficacy score of the mindfulness intervention group significantly improved compared to the control (t = 7.818, P < 0.001), while the awareness of physical and mental health in the mindfulness intervention group significantly improved compared to the control (χ2 = 5.781, P = 0.016).
Conclusion: Mindfulness-based, short-term focused interventions provide modest relief for depression and/or anxiety and are effective in lowering blood pressure and improving self-efficacy scores.
Trial Registration: Chinese Clinical Trial Registry, ChiCTR1900028258. Registered 16 December 2019, https://www.chictr.org.cn/showproj.html?proj=43627 .
(© 2024. The Author(s).)

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2020-2-11-16 2020 Science and Technology Project of Chengguan District, Lanzhou; 2016YJRC-01 Talent Introduction Program of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine; 2020B-153 University Innovation Capacity Improvement Project in Gansu Province; 2021CX69 the Innovation Fund of Postgraduate, Gansu University of Chinese Medicine

Keywords: Anxiety; Blood pressure (BP); Depression; Hypertension; Mindfulness-based therapy

Date Created: 20240502 Date Completed: 20240503 Latest Revision: 20240517

20240518

10.1186/s13063-024-08139-0

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