Elevated resting heart rate is associated with the metabolic syndrome.

Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE

Original Publication: London : BioMed Central, [2002-

Arrhythmias, Cardiac/*physiopathology ; Heart Rate/*physiology ; Metabolic Syndrome/*physiopathology ; Rest/*physiology; Adult ; Arrhythmias, Cardiac/complications ; Arrhythmias, Cardiac/diagnosis ; Cohort Studies ; Cross-Sectional Studies ; Female ; Humans ; Male ; Metabolic Syndrome/complications ; Metabolic Syndrome/diagnosis ; Middle Aged ; Risk Factors

Background: Increased resting heart rate (RHR) may be associated with increased cardiovascular morbidity. Our aim was to explore the possibility that increased RHR is associated with the prevalence of the metabolic syndrome (MetS) in a sample of apparently healthy individuals and those with cardiovascular risk factors.
Methods: We performed a cross-sectional analysis in a large sample of apparently healthy individuals who attended a general health screening program and agreed to participate in our survey. We analyzed a sample of 7706 individuals (5106 men and 2600 women) with 13.2% of men and 8.9% of the women fulfilling the criteria for the MetS. The participants were divided into quintiles of resting heart rate. Multiple adjusted odds ratio was calculated for having the MetS in each quintile compared to the first.
Results: The multi-adjusted odds for the presence of the MetS increased gradually from an arbitrarily defined figure of 1.0 in the lowest RHR quintile (<60 beats per minute (BPM) in men and <64 BPM in women) to 4.1 and 4.2 in men and women respectively in the highest one (>or=80 BPM in men and >or=82 BPM in women).
Conclusion: Raised resting heart rate is significantly associated with the presence of MetS in a group of apparently healthy individuals and those with an atherothrombotic risk. The strength of this association supports the potential presence of one or more shared pathophysiological mechanisms for both RHR and the MetS.

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Date Created: 20091016 Date Completed: 20100524 Latest Revision: 20220410

20231215

PMC2768698

10.1186/1475-2840-8-55

19828043