Testosterone level in aging male with different glucose tolerance state and its association with osteocalcin.

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  • Additional Information
    • Source:
      Publisher: Taylor & Francis Country of Publication: England NLM ID: 9808210 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-0790 (Electronic) Linking ISSN: 13685538 NLM ISO Abbreviation: Aging Male Subsets: MEDLINE
    • Publication Information:
      Publication: 2015- : Abingdon, Oxford : Taylor & Francis
      Original Publication: New York : Parthenon Pub., c1998-
    • Subject Terms:
      Blood Glucose/*analysis ; Glucose Intolerance/*blood ; Osteocalcin/*blood ; Testosterone/*blood; Aged ; Aged, 80 and over ; Biomarkers/blood ; Body Mass Index ; Cholesterol/blood ; Cross-Sectional Studies ; Enzyme-Linked Immunosorbent Assay ; Glucose Intolerance/classification ; Humans ; Linear Models ; Male ; Middle Aged ; Waist Circumference
    • Abstract:
      Objective: To investigate the relationship of testosterone and different glucose tolerance state, and its association with osteocalcin.
      Methods: A cross-sectional study was conducted of 1176 males aged 60-97 years who were arranged for an annual regular checkup from March to May 2012 in Chinese PLA general hospital in Beijing.
      Results: Individuals categorized as having prediabetes or diabetes were more likely to have lower osteocalcin, testosterone, and SHBG levels compared to those with normal glucose tolerance (p < .05 in males). In aging males, after adjusting for age, the negative association between osteocalcin and BMI, waist circumference, FPG, 2hPBG, or TG were significant. And serum TT was negatively associated with BMI, waist circumference, FPG, 2hPBG, or TG independent of age, ALP, Ca, P, VitD, and PTH.
      Conclusions: It showed that serum osteocalcin and TT were closely related with BMI, blood glucose, and TG, which supported the hypothesis that regulation of bone remodeling, energy metabolism, and reproduction are linked.
    • Contributed Indexing:
      Keywords: Testosterone; aging male; blood glucose; diabetes; osteocalcin
    • Accession Number:
      0 (Biomarkers)
      0 (Blood Glucose)
      104982-03-8 (Osteocalcin)
      3XMK78S47O (Testosterone)
      97C5T2UQ7J (Cholesterol)
    • Publication Date:
      Date Created: 20180725 Date Completed: 20190501 Latest Revision: 20190501
    • Publication Date:
      20231215
    • Accession Number:
      10.1080/13685538.2018.1481940
    • Accession Number:
      30039993