Clinical Features of Mpox Patients in Korea: A Multicenter Retrospective Study.

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  • Additional Information
    • Source:
      Publisher: Korean Academy of Medical Science Country of Publication: Korea (South) NLM ID: 8703518 Publication Model: Electronic Cited Medium: Internet ISSN: 1598-6357 (Electronic) Linking ISSN: 10118934 NLM ISO Abbreviation: J Korean Med Sci Subsets: MEDLINE
    • Publication Information:
      Original Publication: Seoul, Korea : Korean Academy of Medical Science, [1986-
    • Subject Terms:
      Mpox (monkeypox)* ; Exanthema*/etiology; Young Adult ; Humans ; Female ; Male ; Adult ; Retrospective Studies ; Republic of Korea/epidemiology ; Sexual Behavior
    • Abstract:
      Background: Mpox is a viral illness with a characteristic skin rash caused by the monkeypox virus. In 2022, Mpox spread throughout the world, and an epidemic through domestic transmission started in South Korea in early 2023. This study aimed to summarize the clinical features of Mpox patients in South Korea.
      Methods: This is a multicenter retrospective study conducted at four hospitals in South Korea. All adult patients diagnosed with Mpox who were admitted to the study hospitals between June 1, 2022 and May 26, 2023 and were discharged by June 30, 2023 were reviewed.
      Results: Sixty patients were included, accounting for 65.9% of Mpox cases reported in South Korea during the study period. Median age was 32 years and 97% (58/60) of patients were male. In total, 85% (51/60) of patients reported their sexual orientation as homosexual or bisexual. The most common route of transmission was sexual or close contact (55/60). Every patient had a skin rash and 88% (53/60) had constitutional symptoms. In total, 42% (25/60) of patients had human immunodeficiency virus and 25% (15/60) had concomitant sexually transmitted infections. Severe manifestations of Mpox were identified in only two patients.
      Conclusion: Mpox patients in South Korea were mainly young adult males and were infected through sexual contact. The clinical outcomes were favorable.
      Competing Interests: The authors have no potential conflicts of interest to disclose.
      (© 2024 The Korean Academy of Medical Sciences.)
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    • Contributed Indexing:
      Keywords: Korea; Monkeypox; Mpox; South Korea
    • Publication Date:
      Date Created: 20240130 Date Completed: 20240131 Latest Revision: 20240201
    • Publication Date:
      20240201
    • Accession Number:
      PMC10825456
    • Accession Number:
      10.3346/jkms.2024.39.e19
    • Accession Number:
      38288533