COVID-19 vaccine uptake, conspiracy theories, and health literacy among Black individuals in Canada: Racial discrimination, confidence in health, and COVID-19 stress as mediators.

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    • Source:
      Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE
    • Publication Information:
      Publication: New York Ny : Wiley-Liss
      Original Publication: New York, Liss.
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    • Abstract:
      Factors influencing vaccine uptake in Black individuals remain insufficiently documented. Understanding the role of COVID-19 related stress, conspiracy theories, health literacy, racial discrimination experiences, and confidence in health authorities can inform programs to increase vaccination coverage. We sought to analyze these factors and vaccine uptake among Black individuals in Canada. A representative sample of 2002 Black individuals from Ontario, Quebec, Alberta, Nova Scotia, New Brunswick, British Columbia, and Manitoba, aged 14 years or older completed questionnaires assessing vaccine uptake, health literacy, conspiracy theories, racial discrimination experiences, COVID-19-related stress, and confidence in health authorities. Mediation analyses were conducted to assess (1) the effect of health literacy on COVID-19 vaccination uptake through confidence and need, COVID-19 related traumatic stress, and racial discrimination, and (2) the effect of conspiracy beliefs on COVID-19 vaccination uptake through the same factors. Overall, 69.57% (95% confidence interval, 67.55%-71.59%) of the participants were vaccinated and 83.48% of them received two or more doses. Those aged 55 years and older were less likely to be vaccinated, as well as those residing in British Columbia and Manitoba. Mediation models showed that the association between health literacy and COVID-19 vaccine uptake was mediated by confidence in health authorities (B = 0.02, p < 0.001), COVID-19-related stress (B = -0.02, p < 0.001), and racial discrimination (B = -0.01, p = 0.032), but both direct and total effects were nonsignificant. Lastly, conspiracy beliefs were found to have a partial mediation effect through the same mediators (B = 0.02, p < 0.001, B = -0.02, p < 0.001, B = -0.01, p = 0.011, respectively). These findings highlight the need for targeted interventions to address vaccine hesitancy and inform approaches to improve access to vaccinations among Black communities.
      (© 2024 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC.)
    • References:
      Government of Canada. COVID-19 Vaccination Coverage by Ethnicity: Insight From the Canadian Community Health Survey (CCHS). Vaccination Coverage in Canada. Government of Canada; 2022. https://www.canada.ca/en/public-health/services/immunization-vaccines/vaccination-coverage/covid-19-additional-doses-results-2022-canadian-community-health-survey.html.
      Government of Canada. COVID-19 Vaccination Coverage in Canada-Canada.ca. Government of Canada; 2022. https://health-infobase.canada.ca/covid-19/vaccination-coverage/archive/2021-08-13/.
      Cénat JM, Noorishad PG, Moshirian Farahi SMM, et al. Prevalence and factors related to COVID-19 vaccine hesitancy and unwillingness in Canada: a systematic review and meta-analysis. J Med Virol. 2023;95(1):e28156. doi:10.1002/jmv.28156.
      Cénat JM, Noorishad PG, Bakombo SM, et al. A systematic review on vaccine hesitancy in Black communities in Canada: critical issues and research failures. Vaccines. 2022;10(11):1937. doi:10.3390/vaccines10111937.
      Piraveenan M, Sawleshwarkar S, Walsh M, et al. Optimal governance and implementation of vaccination programmes to contain the COVID-19 pandemic. R Soc Open Sci. 2021;8(6):210429. doi:10.1098/rsos.210429.
      Rzymski P, Camargo CA Jr, Fal A, et al. COVID-19 vaccine boosters: the good, the bad, and the ugly. Vaccines. 2021;9(11):1299. doi:10.3390/vaccines9111299.
      Gupta S, Aitken N. COVID-19 mortality among racialized populations in Canada and its association with income StatCan COVID-19: data to insights for a better Canada. August 2022. Accessed September 13, 2022. https://www150.statcan.gc.ca/n1/pub/45-28-0001/2022001/article/00010-eng.htm?utm_source=rddt&utm_medium=smo&utm_campaign=statcan-all-content-22-23.
      Cénat JM, Hajizadeh S, Dalexis RD, Ndengeyingoma A, Guerrier M, Kogan C. Prevalence and effects of daily and major experiences of racial discrimination and microaggressions among Black individuals in Canada. J Interpers Violence. 2022;37(17-18):NP16750-NP16778. doi:10.1177/08862605211023493.
      Etowa J, Demeke J, Abrha G, et al. Social determinants of the disproportionately higher rates of COVID-19 infection among African Caribbean and Black (ACB) population: a systematic review protocol. J Public Health Res. 2022;11:2274. doi:10.4081/JPHR.2021.2274.
      Cénat JM. Who is Black? The urgency of accurately defining the Black population when conducting health research in Canada. Can Med Assoc J. 2022;194(27):E948-E949. doi:10.1503/CMAJ.220274.
      Maheux H, Do D. Diversity of the Black population in Canada: an overview. 2019. Accessed March 20, 2020. https://www150.statcan.gc.ca/n1/pub/89-657-x/89-657-x2019002-fra.htm.
      Statistics Canada. 2016 Census of Population. Statistics Canada; 2018. https://www12.statcan.gc.ca/census-recensement/2016/dp-pd/prof/index.cfm?Lang=E.
      Cénat JM, Farahi SMMM, Dalexis RD. Prevalence and determinants of depression, anxiety, and stress symptoms among Black individuals in Canada in the context of the COVID-19 pandemic. Psychiatry Res. 2023;326:115341. doi:10.1016/j.psychres.2023.115341.
      Cénat JM, Moshirian Farahi SMM, Broussard C, Dalexis RD. The state of COVID-19 vaccine confidence and need in Black individuals in Canada: understanding the role of sociodemographic factors, health literacy, conspiracy theories, traumatic stressors and racial discrimination. Vaccine. 2023;42(4): 960-968. doi:10.1016/j.vaccine.2023.10.048.
      Cénat JM, Moshirian Farahi SMM, Bakombo SM, et al. Vaccine mistrust among Black individuals in Canada: the major role of health literacy, conspiracy theories, and racial discrimination in the healthcare system. J Med Virol. 2023;95(4):e28738. doi:10.1002/jmv.28738.
      Kira IA, Shuwiekh HAMM, Rice KG, et al Measuring COVID-19 as traumatic stress: initial psychometrics and validation. J Loss Trauma. 2020;26(3):1-18. doi:10.1080/15325024.2020.1790160.
      Kira IA, Shuwiekh HAM, Ashby JS, Rice KG, Alhuwailah A. Measuring COVID-19 stressors and their impact: the second-order factor model and its four first-order factors: infection fears, economic, grief, and lockdown stressors. J Loss Trauma. 2021;26(8):733-751. doi:10.1080/15325024.2021.1920270.
      Ashby JS, Rice KG, Kira IA, Davari J. The relationship of COVID-19 traumatic stress, cumulative trauma, and race to posttraumatic stress disorder symptoms. J Community Psychol. 2022;50(6):2597-2610. doi:10.1002/jcop.22762.
      Constantinou M, Kagialis A, Karekla M. Covid-19 scientific facts vs. conspiracy theories: is science failing to pass its message? Int J Environ Res Public Health. 2021;18(12):6343. doi:10.3390/ijerph18126343.
      Norman CD, Skinner HA. eHEALS: the eHealth Literacy Scale. J Med Internet Res. 2006;8(4):e507. doi:10.2196/jmir.8.4.e27.
      Williams DR, Yan Yu U, Jackson JS, Anderson NB. Racial differences in physical and mental health. Socio-economic status, stress and discrimination. J Health Psychol. 1997;2(3):335-351. doi:10.1177/135910539700200305.
      Miconi D, Li ZY, Frounfelker RL, Venkatesh V, Rousseau C. Socio-cultural correlates of self-reported experiences of discrimination related to COVID-19 in a culturally diverse sample of Canadian adults. Int J Intercult Relat. 2021;81:176-192. doi:10.1016/j.ijintrel.2021.01.013.
      Cénat JM, Kouamou LN, Moshirian Farahi SMM, et al. Perceived racial discrimination, psychosomatic symptoms, and resilience among Black individuals in Canada: a moderated mediation model. J Psychosom Res. 2022;163:111053. doi:10.1016/j.jpsychores.2022.111053.
      Bogart LM, Dong L, Gandhi P, et al. COVID-19 vaccine intentions and mistrust in a national sample of Black Americans. J Natl Med Assoc. 2022;113(6):599-611. doi:10.1016/j.jnma.2021.05.011.
      Blackburn AM, Han H, Gelpí RA, et al. Mediation analysis of conspiratorial thinking and anti-expert sentiments on vaccine willingness. Health Psychol. 2023;42(4):235-246. doi:10.1037/hea0001268.
      Capasso M, Caso D, Zimet GD. The mediating roles of attitude toward COVID-19 vaccination, trust in science and trust in government in the relationship between anti-vaccine conspiracy beliefs and vaccination intention. Front Psychol. 2022;13:936917. doi:10.3389/fpsyg.2022.936917.
      Kowalska-Duplaga K, Duplaga M. The association of conspiracy beliefs and the uptake of COVID-19 vaccination: a cross-sectional study. BMC Public Health. 2023;23(1):672. doi:10.1186/s12889-023-15603-0.
      Jiang F, Zhao Y, Bai J, et al. Perceived health literacy and COVID-19 vaccine acceptance among Chinese college students: a mediation analysis. PLoS One. 2022;17(9):e0273285. doi:10.1371/journal.pone.0273285.
      Collini F, Bonaccorsi G, Del Riccio M, et al. Does vaccine confidence mediate the relationship between vaccine literacy and influenza vaccination? Exploring determinants of vaccination among staff members of nursing homes in Tuscany, Italy, during the COVID-19 pandemic. Vaccines. 2023;11(8):1375. doi:10.3390/vaccines11081375.
      Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol. 1986;51(6):1173-1182.
      Gunzler D, Chen T, Wu P, Zhang H. Introduction to mediation analysis with structural equation modeling. Shanghai Arch Psychiatry. 2013;25(6):390-394. doi:10.3969/j.issn.1002-0829.2013.06.009.
      Hayes AF. Partial, conditional, and moderated moderated mediation: quantification, inference, and interpretation. Commun Monogr. 2018;85(1):4-40. doi:10.1080/03637751.2017.1352100.
      Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis-Model Numbers. Vol 46. Guilford Press; 2022. http://www.guilford.com/ebooks.
      Ndugga N, Hill L, Artiga S, Parker N. Latest data on COVID-19 vaccinations by race/ethnicity. Kaiser Family Foundation; 2021.
      Chiranjib C, Ashish RS, Manojit B, Govindasamy A, Sang-Soo L. All nations must prioritize the COVID-19 vaccination program for elderly adults urgently. Aging Dis. 2022;12(3):688. doi:10.14336/ad.2021.04016.
      Castro MC, Singer B. Prioritizing COVID-19 vaccination by age. Proc Natl Acad Sci USA. 2021;118(15):e2103700118. doi:10.1073/PNAS.2103700118.
      Soiza RL, Scicluna C, Thomson EC. Efficacy and safety of COVID-19 vaccines in older people. Age Ageing. 2021;50(2):279-283. doi:10.1093/ageing/afaa274.
      Harris OO, Perry TE, Johnson JK, et al. Understanding the concept of trust and other factors related to COVID-19 vaccine intentions among Black/African American older adults prior to vaccine development. SSM Qual Res Health. 2023;3:100230. doi:10.1016/j.ssmqr.2023.100230.
      Abbasi J. Widespread misinformation about infertility continues to create COVID-19 vaccine hesitancy. JAMA. 2022;327(11):1013-1015. doi:10.1001/jama.2022.2404.
      Eissa A, Lofters A, Akor N, Prescod C, Nnorom O. Increasing SARS-CoV-2 vaccination rates among Black people in Canada. Can Med Assoc J. 2021;193(31):E1220-E1221. doi:10.1503/CMAJ.210949.
      Kemei J, Tulli M, Olanlesi-Aliu A, Tunde-Byass M, Salami B. Impact of the COVID-19 pandemic on Black communities in Canada. Int J Environ Res Public Health. 2023;20(2):1580. doi:10.3390/ijerph20021580.
      Wang Y, Thier K, Ntiri SO, Quinn SC, Adebamowo C, Nan X. Beliefs in COVID-19 vaccine misinformation among unvaccinated Black Americans: prevalence, socio-psychological predictors, and consequences. Health Commun. 2023:1-13. doi:10.1080/10410236.2023.2179711.
      Dubé È, Dionne M, Rochette L. Exploring the impact of Quebec's vaccine lottery and vaccine passports on Covid-19 vaccination intention: findings from repeated cross-sectional surveys. Hum Vaccines Immunother. 2022;18(6):2100168. doi:10.1080/21645515.2022.2100168.
      Lessard D, Ortiz-Paredes D, Park H, et al. Barriers and facilitators to COVID-19 vaccine acceptability among people incarcerated in Canadian federal prisons: a qualitative study. Vaccine: X. 2022;10:100150. doi:10.1016/j.jvacx.2022.100150.
      Bogart LM, Dong LU, Gandhi P, et al. What Contributes to COVID-19 Vaccine Hesitancy in Black Communities, and How can it be Addressed? RAND Corporation; 2021. doi:10.7249/rra1110-1.
      Paul E, Fancourt D, Razai M. Racial discrimination, low trust in the health system and COVID-19 vaccine uptake: a longitudinal observational study of 633 UK adults from ethnic minority groups. J R Soc Med. 2022;115:439-447. doi:10.1177/01410768221095241.
      Savoia E, Piltch-Loeb R, Goldberg B, et al. Predictors of COVID-19 vaccine hesitancy: socio-demographics, co-morbidity, and past experience of racial discrimination. Vaccines. 2021;9(7):2021.01.12.21249152. doi:10.3390/vaccines9070767.
      Cénat JM. Complex racial trauma: evidence, theory, assessment, and treatment. Perspectives on Psychological Science. 2023;18(3):675-687. doi:10.1177/17456916221120428.
      Rousseau, C, Gomez-Carrillo, A, & Cénat, JM. Safe enough? Rethinking the concept of cultural safety in healthcare and training. BJPsych. 2022; 221(4): 587-588. https://doi.org/10.1192/bjp.2022.102.
    • Grant Information:
      #469050 Canada CAPMC CIHR
    • Contributed Indexing:
      Keywords: COVID-19 vaccine uptake; COVID-19-related stress; conspiracy theories; health literacy; racial discrimination
    • Accession Number:
      0 (COVID-19 Vaccines)
    • Publication Date:
      Date Created: 20240213 Date Completed: 20240214 Latest Revision: 20240214
    • Publication Date:
      20240214
    • Accession Number:
      10.1002/jmv.29467
    • Accession Number:
      38348886