Influence of Hepatitis C virus genotype and other factors on the viral load.

Publisher: Elsevier Country of Publication: United States NLM ID: 8700903 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1998-3646 (Electronic) Linking ISSN: 02550857 NLM ISO Abbreviation: Indian J Med Microbiol Subsets: MEDLINE

Publication: 2021- : [New York] : Elsevier
Original Publication: New Delhi : Indian Association of Medical Microbiologists

Hepacivirus*/genetics ; Hepacivirus*/classification ; Viral Load* ; Genotype* ; Hepatitis C*/virology; Humans ; Male ; Female ; Adult ; Middle Aged ; Young Adult ; Risk Factors ; Adolescent ; Aged ; Sex Factors

Anti-HCV reactive subjects were selected and relevant data was collected. Viral load and genotype were determined for all patients and were divided into low (<800,000 IU/mL) and high viral load (>800,000 IU/mL). Correlation of viral load with parameters like age, gender, risk factors and genotype etc. was determined by binomial regression. Higher viral load was noted with genotype 4, males and high risk groups like People Who Inject Drugs (PWIDs), blood transfusion before routine testing or frequent transfusion, Intravenous drug therapy and MTP by unregistered medical practitioners (P ≤ 0.5). Prevention and treatment strategies for HCV should be tailored around these areas.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved.)

Keywords: Genotype; Hepatitis C virus; Public health; Risk factors; Viral load

Date Created: 20240316 Date Completed: 20240506 Latest Revision: 20240506

20240507

10.1016/j.ijmmb.2024.100560

38492927