[Lyme disease in Mato Grosso do Sul State, Brazil: report of three clinical cases, including the first of Lyme meningitis in Brazil].

Doença de Lyme em Mato Grosso do Sul: relato de três casos clínicos, incluindo o primeiro relato de meningite de Lyme no Brasil.

Publisher: Faculdade de Medicina da Universidade de São Paulo Country of Publication: Brazil NLM ID: 0415246 Publication Model: Print Cited Medium: Print ISSN: 0041-8781 (Print) Linking ISSN: 00418781 NLM ISO Abbreviation: Rev Hosp Clin Fac Med Sao Paulo Subsets: MEDLINE

Original Publication: São Paulo, Faculdade de Medicina da Universidade de São Paulo

Borrelia Infections/*diagnosis ; Lyme Disease/*diagnosis ; Meningitis, Bacterial/*diagnosis; Adolescent ; Adult ; Borrelia Infections/drug therapy ; Brazil ; Female ; Humans ; Lyme Disease/drug therapy ; Male ; Meningitis, Bacterial/drug therapy

The authors report the occurrence of the first three clinical cases of Lyme disease in Mato Grosso do Sul State, including the first case of Lyme meningitis in Brazil. These were identified by clinical and laboratorial criteria. Anti-Borrelia burgdorferi antibody search was carried out through ELISA and Western Blotting techniques, the former providing identification of IgG class antibodies alone, in one only of those cases. Through Immunoblotting, the following features were found in serum: 5 IgG and 2 IgM bands for the first case; 7 IgG and 2 IgM bands for the second; and 5 IgG and 6 IgM bands for the third. In the latter, presence fo specific antibodies was searched in liquor, due to lymphomonocitary meningitis occurrence, and one IgM band was detected. After antibiotic therapy, all patients exhibited significant clinical and laboratorial improvement in their conditions along with symptom regression to the present moment.

Date Created: 19961101 Date Completed: 19970923 Latest Revision: 20061115

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