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Language : english Publisher : national academy of sciences Filter by : Subject

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Academic Journal

Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function.

Authors : Silberstein, John L.; Du, Jasper; Kun-Wei Chan

Subjects: LIGAND binding (Biochemistry); MAJOR histocompatibility complex; T cells

Source: Proceedings of the National Academy of Sciences of the United States of America; 3/19/2024, Vol. 121 Issue 12, p1-11, 26p

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Academic Journal

Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease.

Authors : Shengnan Zhang; Yu-Qing Liu; Chunyu Jia

Subjects: PARKINSON'S disease; CELL receptors; ALPHA-synuclein

Source: Proceedings of the National Academy of Sciences of the United States of America; 6/29/2021, Vol. 118 Issue 26, p1-12, 12p

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Academic Journal

TCR–pMHC kinetics under force in a cell-free system show no intrinsic catch bond, but a minimal encounter duration before binding.

Authors : Limozin, Laurent; Bridge, Marcus; Bongrand, Pierre

Subjects: T cell receptors; LAMINAR flow; LYMPHOCYTE transformation

Source: Proceedings of the National Academy of Sciences of the United States of America; 8/20/2019, Vol. 116 Issue 34, p16943-16948, 6p

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Academic Journal

Longitudinal multiparameter assay of lymphocyte interactions from onset by microfluidic cell pairing and culture.

Authors : Dura, Burak; Servos, Mariah M.; Barry, Rachel M.

Subjects: CELL communication; MICROFLUIDICS; CELL culture

Source: Proceedings of the National Academy of Sciences of the United States of America; 6/28/2016, Vol. 113 Issue 26, pE3599-E3608, 10p

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Academic Journal

An evolving autoimmune microenvironment regulates the quality of effector T cell restimulation and function.

Authors : Friedman, Rachel S.; Lindsay, Robin S.; Lilly, Jason K.

Subjects: AUTOIMMUNITY; T cells; LYMPHOCYTE transformation

Source: Proceedings of the National Academy of Sciences of the United States of America; 6/24/2014, Vol. 111 Issue 25, p9223-9228, 6p

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Academic Journal

Feedback regulation mediated by Bcl-2 and DARPP-32 regulates inositol 1,4,5-trisphosphate receptor phosphorylation and promotes cell survival.

Authors : Ming-Jin Chang; Fei Zhong; Lavik, Andrew R.

Subjects: CALCIUM; LYMPHOCYTE transformation; T cells

Source: Proceedings of the National Academy of Sciences of the United States of America; 1/21/2014, Vol. 111 Issue 3, p1186-1191, 6p

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Academic Journal

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation.

Authors : Glanville, Jacob; Kuo, Tracy C.; von Büdingen, H.-Christiar

Subjects: AUTOANTIBODIES; VIRUS diseases; IMMUNE response

Source: Proceedings of the National Academy of Sciences of the United States of America; 12/13/2011, Vol. 108 Issue 50, p20066-20071, 6p

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Academic Journal

Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation.

Authors : Michalek, Ryan D.; Gerriets, Valerie A.; Nichols, Amanda G.

Subjects: T cell differentiation; ESTROGEN receptors; GENETIC regulation

Source: Proceedings of the National Academy of Sciences of the United States of America; 11/8/2011, Vol. 108 Issue 45, p18348-18353, 6p

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Academic Journal

Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production.

Authors : Lutz, Johannes; Heideman, Marinus R.; Roth, Edith

Subjects: B cell differentiation; LYMPHOCYTE transformation; MESSENGER RNA

Source: Proceedings of the National Academy of Sciences of the United States of America; 6/28/2011, Vol. 108 Issue 26, p10644-10649, 6p

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Academic Journal

Inhibition of the K+ channel KCa3.1 ameliorates I cell-mediated colitis.

Authors : Di, Lie; Srivastava, Shekhar; Zhdanova, Olga

Subjects: CALCIUM; CELL-mediated cytotoxicity; LABORATORY mice

Source: Proceedings of the National Academy of Sciences of the United States of America; 1/26/2010, Vol. 107 Issue 4, p1541-1546, 6p

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