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Academic Journal

Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions.

Subjects: Genome-Wide Association Study* ; Polymorphism, Single Nucleotide* ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/genetics

  • Source: American journal of human genetics [Am J Hum Genet] 2024 Jun 06; Vol. 111 (6), pp. 1061-1083. Date of Electronic Publication: 2024 May 08.Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A saturated map of common genetic variants associated with human height.

Subjects: Body Height*/Body Height*/Body Height*/genetics ; Polymorphism, Single Nucleotide*/Polymorphism, Single Nucleotide*/Polymorphism, Single Nucleotide*/genetics ; Chromosome Mapping*

  • Source: Nature [Nature] 2022 Oct; Vol. 610 (7933), pp. 704-712. Date of Electronic Publication: 2022 Oct 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

European polygenic risk score for prediction of breast cancer shows similar performance in Asian women.

  • Authors : Ho WK; School of Mathematical Sciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Jalan Broga, Semenyih, 43500, Selangor, Malaysia. .; Cancer Research Malaysia, 1 Jalan SS12/1A, Subang Jaya, 47500, Selangor, Malaysia. .

Subjects: Multifactorial Inheritance* ; Polymorphism, Single Nucleotide*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*diagnosis

  • Source: Nature communications [Nat Commun] 2020 Jul 31; Vol. 11 (1), pp. 3833. Date of Electronic Publication: 2020 Jul 31.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.

Subjects: Genetic Predisposition to Disease* ; Genome-Wide Association Study* ; Polymorphism, Single Nucleotide*

  • Source: Nature genetics [Nat Genet] 2020 Jan; Vol. 52 (1), pp. 56-73. Date of Electronic Publication: 2020 Jan 07.Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The functional ALDH2 polymorphism is associated with breast cancer risk: A pooled analysis from the Breast Cancer Association Consortium.

  • Authors : Ugai T; Division of Cancer Epidemiology and Prevention, Department of Preventive Medicine, Aichi Cancer Center Research Institute, Nagoya, Japan.; Milne RL

Subjects: Polymorphism, Single Nucleotide*; Aldehyde Dehydrogenase, Mitochondrial/Aldehyde Dehydrogenase, Mitochondrial/Aldehyde Dehydrogenase, Mitochondrial/*genetics ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics

  • Source: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2019 Jun; Vol. 7 (6), pp. e707. Date of Electronic Publication: 2019 May 07.Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101603758 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.

  • Authors : Bien SA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA. .; Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA. .

Subjects: Genetic Predisposition to Disease* ; Genome-Wide Association Study*/Genome-Wide Association Study*/Genome-Wide Association Study*/statistics & numerical data ; Polymorphism, Single Nucleotide*

  • Source: Human genetics [Hum Genet] 2019 Apr; Vol. 138 (4), pp. 307-326. Date of Electronic Publication: 2019 Feb 28.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7613873 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovery of common and rare genetic risk variants for colorectal cancer.

  • Authors : Huyghe JR; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Bien SA

Subjects: Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics ; Genetic Predisposition to Disease/Genetic Predisposition to Disease/Genetic Predisposition to Disease/*genetics ; Polymorphism, Single Nucleotide/Polymorphism, Single Nucleotide/Polymorphism, Single Nucleotide/*genetics

  • Source: Nature genetics [Nat Genet] 2019 Jan; Vol. 51 (1), pp. 76-87. Date of Electronic Publication: 2018 Dec 03.Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Subjects: Mutation* ; Polymorphism, Single Nucleotide*; BRCA1 Protein/BRCA1 Protein/BRCA1 Protein/*genetics

  • Source: Nature genetics [Nat Genet] 2017 Dec; Vol. 49 (12), pp. 1767-1778. Date of Electronic Publication: 2017 Oct 23.Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Chromosomes, Human, Pair 5/Chromosomes, Human, Pair 5/Chromosomes, Human, Pair 5/*genetics

  • Source: American journal of human genetics [Am J Hum Genet] 2016 Oct 06; Vol. 99 (4), pp. 903-911. Date of Electronic Publication: 2016 Sep 15.Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

Subjects: Alleles* ; Genetic Predisposition to Disease* ; Polymorphism, Single Nucleotide*

  • Source: Nature communications [Nat Commun] 2016 Sep 07; Vol. 7, pp. 12675. Date of Electronic Publication: 2016 Sep 07.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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