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Academic Journal

Immune-Escape Mutations Are Prevalent among Patients with a Coexistence of HBsAg and Anti-HBs in a Tertiary Liver Center in the United States.

  • Authors : Ali MJ; Liver Center, Division of Gastroenterology and Hepatology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Howard University Hospital, Howard University College of Medicine, Washington, DC 20060, USA.

Subjects: Hepatitis B Surface Antigens*/Hepatitis B Surface Antigens*/Hepatitis B Surface Antigens*/genetics ; Hepatitis B Surface Antigens*/Hepatitis B Surface Antigens*/Hepatitis B Surface Antigens*/immunology ; Hepatitis B virus*/Hepatitis B virus*/Hepatitis B virus*/genetics

  • Source: Viruses [Viruses] 2024 Apr 30; Vol. 16 (5). Date of Electronic Publication: 2024 Apr 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

US Food and Drug Administration Approval Summary: Talazoparib in Combination With Enzalutamide for Treatment of Patients With Homologous Recombination Repair Gene-Mutated Metastatic Castration-Resistant Prostate Cancer.

  • Authors : Heiss BL; Center for Drug Evaluation and Research (CDER), US Food and Drug Administration, Silver Spring, MD.; Chang E

Subjects: Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/drug therapy ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/genetics ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/pathology

  • Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 May 20; Vol. 42 (15), pp. 1851-1860. Date of Electronic Publication: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model:

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Academic Journal

Efficacy of Poly(ADP-ribose) Polymerase Inhibitors by Individual Genes in Homologous Recombination Repair Gene-Mutated Metastatic Castration-Resistant Prostate Cancer: A US Food and Drug Administration Pooled Analysis.

  • Authors : Fallah J; Center for Drug Evaluation and Research (CDER), U.S. Food and Drug Administration, Silver Spring, MD.; Xu J

Subjects: Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/drug therapy ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/genetics ; Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/Prostatic Neoplasms, Castration-Resistant*/pathology

  • Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 May 10; Vol. 42 (14), pp. 1687-1698. Date of Electronic Publication: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model:

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Periodical

White House overhauls rules for risky pathogen research.

Subjects: Gain of Function Mutation*; Humans ; United States

  • Source: Science (New York, N.Y.) [Science] 2024 May 10; Vol. 384 (6696), pp. 611. Date of Electronic Publication: 2024 May 09.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Periodical

US funders to tighten oversight of controversial 'gain of function' research.

Subjects: Research Support as Topic*/Research Support as Topic*/Research Support as Topic*/ethics ; Research Support as Topic*/Research Support as Topic*/Research Support as Topic*/legislation & jurisprudence ; Gain of Function Mutation*

  • Source: Nature [Nature] 2024 May; Vol. 629 (8012), pp. 510-511.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The value of Korean, American, and Chinese ultrasound risk stratification systems combined with BRAF(V600E) mutation for detecting papillary thyroid carcinoma in cytologically indeterminate thyroid nodules.

  • Authors : Lin Y; Department of Pathology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China.

Subjects: Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/genetics ; Thyroid Nodule*/Thyroid Nodule*/Thyroid Nodule*/genetics ; Thyroid Nodule*/Thyroid Nodule*/Thyroid Nodule*/diagnostic imaging

  • Source: Endocrine [Endocrine] 2024 May; Vol. 84 (2), pp. 549-559. Date of Electronic Publication: 2023 Nov 09.Publisher: Humana Press Country of Publication: United States NLM ID: 9434444 Publication Model: Print-Electronic Cited

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Academic Journal

Dynamic analysis of SARS-CoV-2 evolution based on different countries.

  • Authors : Xiao B; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing, China

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/immunology ; COVID-19*/COVID-19*/COVID-19*/epidemiology SARS-CoV-2 variants

  • Source: Gene [Gene] 2024 Jul 20; Vol. 916, pp. 148426. Date of Electronic Publication: 2024 Apr 03.Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Germline pathogenic variants associated with triple-negative breast cancer in US Hispanic and Guatemalan women using hospital and community-based recruitment strategies.

  • Authors : Godinez Paredes JM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Gaithersburg, MD, USA.; Rodriguez I

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/genetics ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/ethnology

  • Source: Breast cancer research and treatment [Breast Cancer Res Treat] 2024 Jun; Vol. 205 (3), pp. 567-577. Date of Electronic Publication: 2024 Mar 23.Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Editorial & Opinion

The American Academy of Microbiology discusses gain-of-function research of concern (GOFROC) and enhanced potential pandemic pathogens (ePPP).

  • Authors : Casadevall A; Former Chair of the American Academy of Microbiology Committee of Governors, Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, USA.; Imperiale MJ

Subjects: Gain of Function Mutation* ; Pandemics*/Pandemics*/Pandemics*/prevention & control; Humans

  • Source: MBio [mBio] 2024 Jan 16; Vol. 15 (1), pp. e0276123. Date of Electronic Publication: 2023 Dec 11.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model:

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Academic Journal

Different selection dynamics of S and RdRp between SARS-CoV-2 genomes with and without the dominant mutations.

  • Authors : Koçhan N; Izmir Biomedicine and Genome Center (IBG), Izmir, Turkey.; Eskier D

Subjects: Genome, Viral* ; Point Mutation*; COVID-19/COVID-19/COVID-19/*epidemiology

  • Source: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2021 Jul; Vol. 91, pp. 104796. Date of Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 101084138 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  3,963 results for ""Mutation""