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Academic Journal

Genetic insights into the age-specific biological mechanisms governing human ovarian aging.

Subjects: *DNA repair; *OVARIAN reserve; *HUMAN phenotypeUNITED Kingdom

  • Source: American Journal of Human Genetics. Sep2023, Vol. 110 Issue 9, p1549-1563. 15p.

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Academic Journal

Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology.

  • Authors : SenGupta T; Department of Clinical Molecular Biology, University of Oslo, Oslo, Norway; Department of Clinical Molecular Biology, Akershus University Hospital, Lørenskog, Norway.

Subjects: Aging*; DNA Repair/DNA Repair/DNA Repair/*physiology ; DNA, Single-Stranded/DNA, Single-Stranded/DNA, Single-Stranded/*metabolism

  • Source: Cell reports [Cell Rep] 2021 Sep 07; Vol. 36 (10), pp. 109668.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium:

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Academic Journal

Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage.

  • Authors : Chesnokova V; Pituitary Center, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Zonis S

Subjects: Aging* ; DNA Damage*; Carrier Proteins/Carrier Proteins/Carrier Proteins/*physiology

  • Source: Cell reports [Cell Rep] 2021 Dec 14; Vol. 37 (11), pp. 110068.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium:

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Academic Journal

Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging.

  • Authors : Huang J; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.; Zhou Q

Subjects: DNA Repair*; Aging/Aging/Aging/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism

  • Source: Molecular cell [Mol Cell] 2020 Sep 03; Vol. 79 (5), pp. 824-835.e5. Date of Electronic Publication: 2020 Jul 09.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Cytoplasmic DNA sensing by KU complex in aged CD4 + T cell potentiates T cell activation and aging-related autoimmune inflammation.

  • Authors : Wang Y; CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.; Fu Z

Subjects: Aging/Aging/Aging/*immunology ; Autoimmune Diseases/Autoimmune Diseases/Autoimmune Diseases/*immunology ; CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/*immunology

  • Source: Immunity [Immunity] 2021 Apr 13; Vol. 54 (4), pp. 632-647.e9. Date of Electronic Publication: 2021 Mar 04.Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Do DNA Double-Strand Breaks Drive Aging?

  • Authors : White RR; Department of Genetics, Albert Einstein College of Medicine, 1301 Morris Park Ave., Bronx, NY 10461, USA. Electronic address: .; Vijg J

Subjects: DNA Breaks, Double-Stranded* ; DNA Repair* ; Gene Expression Regulation*

  • Source: Molecular cell [Mol Cell] 2016 Sep 01; Vol. 63 (5), pp. 729-38.Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium:

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Academic Journal

IL-4-ever young: Type 2 cytokine signaling in macrophages slows aging.

Subjects: *MACROPHAGES; *CELLULAR aging; *AGING

  • Source: Immunity (10747613). Mar2024, Vol. 57 Issue 3, p403-406. 4p.

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Academic Journal

Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes.

  • Authors : Zelazowski MJ; Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Smithville, TX 78957, USA.; Sandoval M

Subjects: Aging* ; Chromosome Segregation* ; Meiosis*

  • Source: Cell [Cell] 2017 Oct 19; Vol. 171 (3), pp. 601-614.e13. Date of Electronic Publication: 2017 Sep 21.Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson's Disease.

  • Authors : Sepe S; Department of Molecular Genetics, Erasmus Medical Center, 3015 Rotterdam, the Netherlands.; Milanese C

Subjects: DNA Repair*; Aging/Aging/Aging/*pathology ; Parkinson Disease/Parkinson Disease/Parkinson Disease/*pathology

  • Source: Cell reports [Cell Rep] 2016 May 31; Vol. 15 (9), pp. 1866-75. Date of Electronic Publication: 2016 May 19.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited

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Academic Journal

Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation.

  • Authors : Foronda M; Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.; Martínez P

Subjects: Adult Stem Cells/Adult Stem Cells/Adult Stem Cells/*metabolism ; Aging/Aging/Aging/*genetics ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*genetics

  • Source: Cell reports [Cell Rep] 2014 Jul 24; Vol. 8 (2), pp. 487-500. Date of Electronic Publication: 2014 Jul 17.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited

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