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Academic Journal

Motif A of bacteriophage T4 DNA polymerase: role in primer extension and DNA replication fidelity. Isolation of new antimutator and mutator DNA polymerases.

Subjects: DNA Primers* ; DNA Replication* ; Mutation*

  • Source: The Journal of biological chemistry [J Biol Chem] 1994 Feb 25; Vol. 269 (8), pp. 5635-43.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

APOBEC3-induced mutation of the hepatitis virus B DNA genome occurs during its viral RNA reverse transcription into (-)-DNA.

  • Authors : Chen Z; Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.; Eggerman TL

Subjects: Mutation*; APOBEC Deaminases/APOBEC Deaminases/APOBEC Deaminases/*metabolism ; DNA, Viral/DNA, Viral/DNA, Viral/*genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2021 Aug; Vol. 297 (2), pp. 100889. Date of Electronic Publication: 2021 Jun 25.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Impact of primer-induced conformational dynamics of HIV-1 reverse transcriptase on polymerase translocation and inhibition.

  • Authors : Auger A; Merck Frosst Centre for Therapeutic Research, Kirkland, Quebec, Canada.; Beilhartz GL

Subjects: DNA Primers/DNA Primers/DNA Primers/*chemistry ; DNA, Viral/DNA, Viral/DNA, Viral/*chemistry ; HIV Reverse Transcriptase/HIV Reverse Transcriptase/HIV Reverse Transcriptase/*antagonists & inhibitors

  • Source: The Journal of biological chemistry [J Biol Chem] 2011 Aug 26; Vol. 286 (34), pp. 29575-83. Date of Electronic Publication: 2011 Jul 07.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect.

  • Authors : Gao L; Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA.; Hanson MN

Subjects: Mutation, Missense*; DNA Primers/DNA Primers/DNA Primers/*chemistry ; DNA, Viral/DNA, Viral/DNA, Viral/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 2008 Apr 04; Vol. 283 (14), pp. 9196-205. Date of Electronic Publication: 2008 Jan 24.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots.

  • Authors : Bebenek K; Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709.; Abbotts J

Subjects: DNA Replication* ; Mutation*; DNA, Viral/DNA, Viral/DNA, Viral/*biosynthesis

  • Source: The Journal of biological chemistry [J Biol Chem] 1993 May 15; Vol. 268 (14), pp. 10324-34.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Mutation spectrum of copper-induced DNA damage.

  • Authors : Tkeshelashvili LK; Joseph Gottstein Memorial Cancer Research Laboratory, Department of Pathology, University of Washington, School of Medicine, Seattle 98195.; McBride T

Subjects: DNA Damage* ; Mutation*; Copper/Copper/Copper/*toxicity

  • Source: The Journal of biological chemistry [J Biol Chem] 1991 Apr 05; Vol. 266 (10), pp. 6401-6.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Mutations altering a structurally conserved loop-helix-loop region of a viral packaging motor change DNA translocation velocity and processivity.

  • Authors : Tsay JM; Department of Physics, University of California at San Diego, La Jolla, CA 92093, USA.; Sippy J

Subjects: Mutation*; DNA/DNA/DNA/*genetics ; DNA, Viral/DNA, Viral/DNA, Viral/*genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 2010 Jul 30; Vol. 285 (31), pp. 24282-9. Date of Electronic Publication: 2010 Jun 04.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Increased DNA unwinding efficiency of bacteriophage T7 DNA helicase mutant protein 4A'/E348K.

  • Authors : Washington MT; Department of Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA.; Patel SS

Subjects: Mutation*; Bacteriophage T7/Bacteriophage T7/Bacteriophage T7/*metabolism ; DNA Helicases/DNA Helicases/DNA Helicases/*genetics

  • Source: The Journal of biological chemistry [J Biol Chem] 1998 Apr 03; Vol. 273 (14), pp. 7880-7.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Specific function of DNA ligase I in simian virus 40 DNA replication by human cell-free extracts is mediated by the amino-terminal non-catalytic domain.

  • Authors : Mackenney VJ; Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms, Hertfordshire EN6 3LD, United Kingdom.; Barnes DE

Subjects: DNA Replication* ; Mutation*; DNA Ligases/DNA Ligases/DNA Ligases/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 1997 Apr 25; Vol. 272 (17), pp. 11550-6.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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Academic Journal

Step-arrest mutants of phage Mu transposase. Implications in DNA-protein assembly, Mu end cleavage, and strand transfer.

  • Authors : Kim K; Department of Microbiology, University of Texas at Austin 78712.; Namgoong SY

Subjects: Mutation*; Bacteriophage mu/Bacteriophage mu/Bacteriophage mu/*enzymology ; DNA, Viral/DNA, Viral/DNA, Viral/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 1995 Jan 20; Vol. 270 (3), pp. 1472-9.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID:

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