Search Results

Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells.

• Authors : Li L; Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, MD, USA.; Zou J

Subjects: Annexin A5/Annexin A5/Annexin A5/*administration & dosage ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*administration & dosage ; Apoptosis/Apoptosis/Apoptosis/*drug effects

• Source: Nature biomedical engineering [Nat Biomed Eng] 2020 Nov; Vol. 4 (11), pp. 1102-1116. Date of Electronic Publication: 2020 Aug 17.Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited

Record details

Combination of ruxolitinib with ABT-737 exhibits synergistic effects in cells carrying concurrent JAK2V617F and ASXL1 mutations.

• Authors : Yuan, Jiajia; Song, Junzhe; Chen, Chao

Subjects: DISEASE progression; GENETIC mutation; COMBINATION drug therapy

• Source: Investigational New Drugs; Dec2022, Vol. 40 Issue 6, p1194-1205, 12p

Record details

Letter to Editor: Treatment with the apoptosis inhibitor asunercept reduces clone sizes in patients with lower risk myelodysplastic neoplasms.

• Authors : Zaidi, Syeda Dua e Zehra; Fatima Zaidi, Syeda Mahrukh; Rangwala, Burhanuddin Sohail

Subjects: MOLECULAR cloning; AZACITIDINE; APOPTOSIS

• Source: Annals of Hematology; Jun2024, Vol. 103 Issue 6, p2163-2164, 2p

Record details

Hippo pathway-related genes expression is deregulated in myeloproliferative neoplasms.

• Authors : Cacemiro, Maira da Costa; Cominal, Juçara Gastaldi; Pereira, Luiz Miguel

• Source: Medical Oncology; Aug2022, Vol. 39 Issue 8, p1-11, 11p

Record details

Bcl-2 and Noxa are potential prognostic indicators for patients with gastroenteropancreatic neuroendocrine neoplasms.

• Authors : Guo, Yu; Zhang, Lin; Zhang, Ning

• Source: Endocrine (1355008X); Oct2022, Vol. 78 Issue 1, p159-168, 10p

Record details

Phenformin increases early hematopoietic progenitors in the Jak2V617F murine model.

• Authors : Alves-Silva, Antônio Bruno; Fenerich, Bruna Alves; Fonseca, Natasha Peixoto

Subjects: IN vitro studies; GENETIC mutation; POLYCYTHEMIA vera

• Source: Investigational New Drugs; Jun2022, Vol. 40 Issue 3, p576-585, 10p

Record details

Deletion of Stat3 enhances myeloid cell expansion and increases the severity of myeloproliferative neoplasms in Jak2V617F knock-in mice.

• Authors : Yan, D; Jobe, F; Hutchison, R E

Subjects: CELL metabolism; ANIMAL experimentation; APOPTOSIS

• Source: Leukemia (08876924); Oct2015, Vol. 29 Issue 10, p2050-2061, 12p, 1 Color Photograph, 6 Graphs

Record details

Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids.

• Authors : Harter MF; Institute of Human Biology (IHB), Roche Innovation Center Basel, Basel, Switzerland.; Gustave Roussy Cancer Campus, University Paris-Saclay, Paris, France.

Subjects: Antibodies, Bispecific*/Antibodies, Bispecific*/Antibodies, Bispecific*/immunology ; Antibodies, Bispecific*/Antibodies, Bispecific*/Antibodies, Bispecific*/pharmacology ; Organoids*/Organoids*/Organoids*/immunology

• Source: Nature biomedical engineering [Nat Biomed Eng] 2024 Apr; Vol. 8 (4), pp. 345-360. Date of Electronic Publication: 2023 Dec 19.Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited

Record details

Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2V617F cells.

• Authors : Machado-Neto, João Agostinho; Coelho-Silva, Juan Luiz; Santos, Fábio Pires de Souza

Subjects: AUTOPHAGY; GENES; MYELOPROLIFERATIVE neoplasms

• Source: Investigational New Drugs; Jun2020, Vol. 38 Issue 3, p733-745, 13p

Record details

Cotargeting the JAK/STAT signaling pathway and histone deacetylase by ruxolitinib and vorinostat elicits synergistic effects against myeloproliferative neoplasms.

• Authors : Hao, Xing; Xing, Wen; Yuan, Jiajia

Subjects: ANIMAL experimentation; ANTINEOPLASTIC agents; APOPTOSIS

• Source: Investigational New Drugs; Jun2020, Vol. 38 Issue 3, p610-620, 11p

Record details