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PBPK Modeling of the Effect of Reduced Kidney Function on the Pharmacokinetics of Drugs Excreted Renally by Organic Anion Transporters.

• Authors : Hsueh CH; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA.; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA.

Subjects: Renal Elimination*; Organic Anion Transporters/Organic Anion Transporters/Organic Anion Transporters/*metabolism ; Pharmaceutical Preparations/Pharmaceutical Preparations/Pharmaceutical Preparations/*urine

• Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2018 Mar; Vol. 103 (3), pp. 485-492. Date of Electronic Publication: 2017 Jul 24.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium:

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Risk-benefit perception of pregnancy among breast cancer survivors.

• Authors : Hsieh PL; Department of Nursing, Mackay Medical College, New Taipei City, Taiwan.; Huang SM

Subjects: Reproductive Health* ; Risk Assessment* ; Survivors*

• Source: European journal of cancer care [Eur J Cancer Care (Engl)] 2018 Mar; Vol. 27 (2), pp. e12696. Date of Electronic Publication: 2017 Apr 25.Publisher: Wiley Country of Publication: England NLM ID: 9301979 Publication Model: Print-Electronic Cited Medium:

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Toward greater insights on pharmacokinetics and exposure-response relationships for therapeutic biologics in oncology drug development.

• Authors : Wang Y; Office of Clinical Pharmacology, Office of Translational Sciences, US Food and Drug Administration, Silver Spring, Maryland, USA.; Booth B

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacokinetics ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Biological Products/Biological Products/Biological Products/*pharmacokinetics

• Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2017 May; Vol. 101 (5), pp. 582-584. Date of Electronic Publication: 2017 Mar 15.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium:

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Cancer Therapy: Shooting for the Moon.

• Authors : Lee J; Office of the Director, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.; Blumenthal GM

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/classification ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/economics ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

• Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2017 May; Vol. 101 (5), pp. 552-558.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print Cited Medium: Internet

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Systematic and quantitative assessment of the effect of chronic kidney disease on CYP2D6 and CYP3A4/5.

• Authors : Yoshida K; Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.; Sun B

Subjects: Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*genetics ; Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/Cytochrome P-450 CYP3A/*genetics ; Pharmaceutical Preparations/Pharmaceutical Preparations/Pharmaceutical Preparations/*metabolism

• Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2016 Jul; Vol. 100 (1), pp. 75-87. Date of Electronic Publication: 2016 Mar 07.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium:

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Precision Medicine.

• Authors : Pacanowski M; U.S. Food and Drug Administration, Office of Clinical Pharmacology, Silver Spring, Maryland, USA.; Huang SM

Subjects: Precision Medicine/Precision Medicine/Precision Medicine/*trends; Biomarkers ; Drug Design

• Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2016 Feb; Vol. 99 (2), pp. 124-9.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print Cited Medium: Internet

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Organ Impairment-Drug-Drug Interaction Database: A Tool for Evaluating the Impact of Renal or Hepatic Impairment and Pharmacologic Inhibition on the Systemic Exposure of Drugs.

• Authors : Yeung CK; Department of Pharmacy, School of Pharmacy, University of Washington Seattle, Washington, USA ; Drug Interaction Database Program, University of Washington Seattle, Washington, USA.

• Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2015 Aug; Vol. 4 (8), pp. 489-94. Date of Electronic Publication: 2015 Jul 14.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium:

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Application of Physiologically Based Pharmacokinetic (PBPK) Modeling to Support Dose Selection: Report of an FDA Public Workshop on PBPK.

• Authors : Wagner C; Office of Clinical Pharmacology, Office of Translational Sciences, US Food and Drug Administration, Silver Spring Maryland, USA.; Zhao P

• Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2015 Apr; Vol. 4 (4), pp. 226-30. Date of Electronic Publication: 2015 Apr 17.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium:

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Novel approaches to address challenges in global drug development.

• Authors : Smith BP; Novartis Pharmaceuticals, East Hanover, New Jersey, USA.; Huang SM

Subjects: Internationality*; Drug Discovery/Drug Discovery/Drug Discovery/*methods ; Drug Discovery/Drug Discovery/Drug Discovery/*trends

• Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2015 Mar; Vol. 97 (3), pp. 196-9. Date of Electronic Publication: 2015 Jan 22.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium:

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Intelligent pharmaceuticals: beyond the tipping point.

• Authors : Honig P; Collegeville, Pennsylvania, USA.; Huang SM

Subjects: Drug Design* ; Pharmaceutical Preparations*; Drug Industry/Drug Industry/Drug Industry/*trends

• Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2014 May; Vol. 95 (5), pp. 455-9.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print Cited Medium: Internet

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