Search Results

Lowering Mutant Huntingtin Levels and Toxicity: Autophagy-Endolysosome Pathways in Huntington's Disease.

• Authors : Valionyte E; Peninsula Schools of Medicine and Dentistry, Institute of Translational and Stratified Medicine, University of Plymouth, Research Way, Plymouth PL6 8BU, UK.; Yang Y

Subjects: Autophagy*; Huntingtin Protein/Huntingtin Protein/Huntingtin Protein/*deficiency ; Huntington Disease/Huntington Disease/Huntington Disease/*metabolism

• Source: Journal of molecular biology [J Mol Biol] 2020 Apr 03; Vol. 432 (8), pp. 2673-2691. Date of Electronic Publication: 2019 Nov 29.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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A clinical study and future prospects for bioactive compounds and semi-synthetic molecules in the therapies for Huntington's disease.

• Authors : Islam MR; Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, 1207, Dhaka, Bangladesh.; Jony MH

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism ; Biological Products*/Biological Products*/Biological Products*/therapeutic use ; Neuroprotective Agents*/Neuroprotective Agents*/Neuroprotective Agents*/pharmacology

• Source: Molecular neurobiology [Mol Neurobiol] 2024 Mar; Vol. 61 (3), pp. 1237-1270. Date of Electronic Publication: 2023 Sep 12.Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Dose-dependent reduction of somatic expansions but not Htt aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111 mice.

• Authors : Driscoll, Rachelle; Hampton, Lucas; Abraham, Neeta A.

Subjects: HUNTINGTIN protein; RNA interference; HUNTINGTON disease

• Source: Scientific Reports; 1/24/2024, Vol. 14 Issue 1, p1-11, 11p

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Gut-Brain Axis Deregulation and Its Possible Contribution to Neurodegenerative Disorders.

• Authors : Villavicencio-Tejo F; Laboratory of Neurodegenerative Diseases, Facultad de Ciencias de La Salud, Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, El Llano Subercaseaux 2801, 5to Piso, San Miguel 8910060, Santiago, Chile.; Olesen MA

Subjects: Amyotrophic Lateral Sclerosis* ; Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/physiology ; Neurodegenerative Diseases*/Neurodegenerative Diseases*/Neurodegenerative Diseases*/pathology

• Source: Neurotoxicity research [Neurotox Res] 2023 Dec 16; Vol. 42 (1), pp. 4. Date of Electronic Publication: 2023 Dec 16.Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-3524

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Dissecting the Relationship Between Neuropsychiatric and Neurodegenerative Disorders.

• Authors : Gupta R; Molecular Neuroscience and Functional Genomics Laboratory, Department of Biotechnology, Delhi Technological University, Shahbad Daulatpur, Bawana Road, New Delhi, Delhi, 110042, India.; Advani D

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Parkinson Disease* ; Huntington Disease*

• Source: Molecular neurobiology [Mol Neurobiol] 2023 Nov; Vol. 60 (11), pp. 6476-6529. Date of Electronic Publication: 2023 Jul 17.Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The translational potential of cholesterol-based therapies for neurological disease.

• Authors : Valenza M; Department of Biosciences, University of Milan, Milan, Italy. .; Istituto Nazionale di Genetica Molecolare 'Romeo ed Enrica Invernizzi', Milan, Italy. .

Subjects: Cholesterol*/Cholesterol*/Cholesterol*/metabolism ; Huntington Disease*/Huntington Disease*/Huntington Disease*/therapy ; Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism

• Source: Nature reviews. Neurology [Nat Rev Neurol] 2023 Oct; Vol. 19 (10), pp. 583-598. Date of Electronic Publication: 2023 Aug 29.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500072 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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CRISPR-Cas9 mediated genome editing of Huntington's disease neurospheres.

• Authors : Han JY; Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, South Korea.; Seo J

Subjects: Brain-Derived Neurotrophic Factor*/Brain-Derived Neurotrophic Factor*/Brain-Derived Neurotrophic Factor*/genetics ; Brain-Derived Neurotrophic Factor*/Brain-Derived Neurotrophic Factor*/Brain-Derived Neurotrophic Factor*/metabolism ; Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism

• Source: Molecular biology reports [Mol Biol Rep] 2023 Mar; Vol. 50 (3), pp. 2127-2136. Date of Electronic Publication: 2022 Dec 23.Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4978

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Ginsenoside Rg1 exerts neuroprotective effects in 3-nitropronpionic acid-induced mouse model of Huntington's disease via suppressing MAPKs and NF-κB pathways in the striatum.

• Authors : Yang X; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.; Chu SF

Subjects: Corpus Striatum/Corpus Striatum/Corpus Striatum/*metabolism ; Ginsenosides/Ginsenosides/Ginsenosides/*pharmacology ; Huntington Disease/Huntington Disease/Huntington Disease/*metabolism

• Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2021 Sep; Vol. 42 (9), pp. 1409-1421. Date of Electronic Publication: 2020 Nov 19.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Fibroblast Growth Factor 9 Stimulates Neuronal Length Through NF-kB Signaling in Striatal Cell Huntington's Disease Models.

• Authors : Yusuf IO; Taiwan International Graduate Program in Interdisciplinary Neuroscience, National Cheng Kung University and Academia Sinica, Taipei, 11529, Taiwan.; Institute of Clinical Medicine, Taipei, Taiwan.

Subjects: Corpus Striatum/Corpus Striatum/Corpus Striatum/*drug effects ; Fibroblast Growth Factor 9/Fibroblast Growth Factor 9/Fibroblast Growth Factor 9/*pharmacology ; Huntington Disease/Huntington Disease/Huntington Disease/*metabolism

• Source: Molecular neurobiology [Mol Neurobiol] 2021 May; Vol. 58 (5), pp. 2396-2406. Date of Electronic Publication: 2021 Jan 09.Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The Role of Glial Cells in Synaptic Dysfunction: Insights into Alzheimer's Disease Mechanisms

• Authors : Yu, Yang; Chen, Ran; Mao, Kaiyue

• Source: Aging and Disease. April, 2024, Vol. 15 Issue 2, p459, 21 p.

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