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Academic Journal

Phosphoenolpyruvate carboxykinase-1 targeted siRNA promotes wound healing in type 2 diabetic mice by restoring glucose homeostasis.

  • Authors : Bajaj G; National Agri-Food Biotechnology Institute (NABI), Sector-81, S.A.S Nagar, Mohali 140306, Punjab, India; Department of Biotechnology, Panjab University, Sector 25, Chandigarh 160014, India.

Subjects: Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/genetics ; Wound Healing*

  • Source: International journal of biological macromolecules [Int J Biol Macromol] 2024 Jun; Vol. 270 (Pt 2), pp. 132504. Date of Electronic Publication: 2024 May 20.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Dulaglutide restores endothelial progenitor cell levels in diabetic mice and mitigates high glucose-induced endothelial injury through SIRT1-mediated mitochondrial fission.

  • Authors : Mei X; Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China; Department of Endocrinology and Metabolism, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, China.

Subjects: Immunoglobulin Fc Fragments*/Immunoglobulin Fc Fragments*/Immunoglobulin Fc Fragments*/pharmacology ; Glucagon-Like Peptides*/Glucagon-Like Peptides*/Glucagon-Like Peptides*/analogs & derivatives ; Glucagon-Like Peptides*/Glucagon-Like Peptides*/Glucagon-Like Peptides*/pharmacology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jul 05; Vol. 716, pp. 150002. Date of Electronic Publication: 2024 Apr 25.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The paradox of fatty-acid β-oxidation in muscle insulin resistance: Metabolic control and muscle heterogeneity.

  • Authors : Vieira-Lara MA; Laboratory of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Electronic address: .; Bakker BM

Subjects: Insulin Resistance* ; Muscle, Skeletal*/Muscle, Skeletal*/Muscle, Skeletal*/metabolism ; Oxidation-Reduction*

  • Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Jun; Vol. 1870 (5), pp. 167172. Date of Electronic Publication: 2024 Apr 15.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults.

  • Authors : Nakhe AY; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, United States.; Dadi PK

Subjects: Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/genetics ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism ; Glucagon*/Glucagon*/Glucagon*/metabolism Maturity-Onset Diabetes of the Young, Type 2

  • Source: ELife [Elife] 2024 May 03; Vol. 12. Date of Electronic Publication: 2024 May 03.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Glucagon kinetics assessed by mathematical modelling during oral glucose administration in people spanning from normal glucose tolerance to type 2 diabetes.

  • Authors : Andreozzi F; Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, Catanzaro, Italy.; Mancuso E

Subjects: Blood Glucose*/Blood Glucose*/Blood Glucose*/metabolism ; Blood Glucose*/Blood Glucose*/Blood Glucose*/analysis ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/blood

  • Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 Apr 12; Vol. 15, pp. 1376530. Date of Electronic Publication: 2024 Apr 12 (Print Publication: 2024).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print

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Academic Journal

Indole-3-propionic acid attenuates high glucose induced ER stress response and augments mitochondrial function by modulating PERK-IRE1-ATF4-CHOP signalling in experimental diabetic neuropathy.

  • Authors : Gundu C; Molecular and Cellular Neuroscience Laboratory, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Hyderabad, Balanagar, India.; Arruri VK

Subjects: Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/drug effects ; Indoles*/Indoles*/Indoles*/pharmacology ; Diabetic Neuropathies*/Diabetic Neuropathies*/Diabetic Neuropathies*/metabolism

  • Source: Archives of physiology and biochemistry [Arch Physiol Biochem] 2024 Jun; Vol. 130 (3), pp. 243-256. Date of Electronic Publication: 2022 Jan 11.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9510153 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of Dapagliflozin on Renal and Hepatic Glucose Kinetics in T2D and NGT Subjects.

  • Authors : Chen X; Division of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX.; Tripathy D

Subjects: Glucosides*/Glucosides*/Glucosides*/therapeutic use ; Glucosides*/Glucosides*/Glucosides*/pharmacology ; Benzhydryl Compounds*/Benzhydryl Compounds*/Benzhydryl Compounds*/therapeutic use

  • Source: Diabetes [Diabetes] 2024 Jun 01; Vol. 73 (6), pp. 896-902.Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited

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Academic Journal

Glucose uptake in trophoblasts of GDM mice is regulated by the AMPK-CLUT3 signaling pathway.

  • Authors : Xiao Z; Department of Obstetrics, Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, People's Republic of China.; Liu X

Subjects: Trophoblasts*/Trophoblasts*/Trophoblasts*/metabolism ; Glucose*/Glucose*/Glucose*/metabolism ; AMP-Activated Protein Kinases*/AMP-Activated Protein Kinases*/AMP-Activated Protein Kinases*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 May 27; Vol. 14 (1), pp. 12051. Date of Electronic Publication: 2024 May 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism.

  • Authors : Wahlström A; Wallenberg Laboratory and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Brumbaugh A

Subjects: Deoxycholic Acid*/Deoxycholic Acid*/Deoxycholic Acid*/metabolism ; Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/physiology ; Glucose*/Glucose*/Glucose*/metabolism

  • Source: Nature communications [Nat Commun] 2024 May 20; Vol. 15 (1), pp. 4276. Date of Electronic Publication: 2024 May 20.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Comparison of an oral mixed meal plus arginine and intravenous glucose, GLP-1 plus arginine to unmask residual islet function in longstanding type 1 diabetes.

  • Authors : Uitbeijerse BS; Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.; Nijhoff MF

Subjects: Arginine*/Arginine*/Arginine*/administration & dosage ; Arginine*/Arginine*/Arginine*/pharmacology ; C-Peptide*/C-Peptide*/C-Peptide*/blood

  • Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2024 May 01; Vol. 326 (5), pp. E673-E680. Date of Electronic Publication: 2024 Mar 06.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium:

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