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Academic Journal

RUNX1 C-terminal mutations impair blood cell differentiation by perturbing specific enhancer-promoter networks.

  • Authors : Jayne ND; Moores UCSD Cancer Center, University of California San Diego, La Jolla, CA.; School of Biological Sciences, University of California San Diego, La Jolla, CA.

Subjects: Core Binding Factor Alpha 2 Subunit*/Core Binding Factor Alpha 2 Subunit*/Core Binding Factor Alpha 2 Subunit*/genetics ; Core Binding Factor Alpha 2 Subunit*/Core Binding Factor Alpha 2 Subunit*/Core Binding Factor Alpha 2 Subunit*/metabolism ; Cell Differentiation*/Cell Differentiation*/Cell Differentiation*/genetics

  • Source: Blood advances [Blood Adv] 2024 May 28; Vol. 8 (10), pp. 2410-2423.Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet

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Academic Journal

Effect of DNMT3A R882H Hot Spot Mutations on DDX43 Promoter Methylation in Acute Myeloid Leukemia.

  • Authors : Tabatabaei T; Department of Hematology and Blood Transfusion, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran.; Rezvany MR

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics ; DNA Methyltransferase 3A*/DNA Methyltransferase 3A*/DNA Methyltransferase 3A*/genetics ; Promoter Regions, Genetic*/Promoter Regions, Genetic*/Promoter Regions, Genetic*/genetics

  • Source: BioMed research international [Biomed Res Int] 2024 May 21; Vol. 2024, pp. 9625043. Date of Electronic Publication: 2024 May 21 (Print Publication: 2024).Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

A radiomics-based nomogram may be useful for predicting telomerase reverse transcriptase promoter mutation status in adult glioblastoma.

  • Authors : Li Y; Department of Neurosurgery, Liuzhou Worker's Hospital, Guangxi, China.; Chen L

Subjects: Telomerase*/Telomerase*/Telomerase*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/diagnostic imaging

  • Source: Brain and behavior [Brain Behav] 2024 May; Vol. 14 (5), pp. e3528.Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101570837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Precore mutation enhances viral replication to facilitate persistent infection especially in HBeAg-negative patients.

  • Authors : Li G; Peking University People's Hospital, Peking University Hepatology Institute, Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases, Beijing International Cooperation Base for Science and Technology on NAFLD Diagnosis, Beijing, 100044, China.; Yang D

Subjects: Virus Replication* ; Hepatitis B virus*/Hepatitis B virus*/Hepatitis B virus*/genetics ; Hepatitis B virus*/Hepatitis B virus*/Hepatitis B virus*/physiology

  • Source: Virologica Sinica [Virol Sin] 2024 Apr; Vol. 39 (2), pp. 319-330. Date of Electronic Publication: 2024 Mar 14.Publisher: Elsevier B.V. on behalf of KeAi Communications Co. Ltd Country of Publication: Netherlands NLM ID: 101514185 Publication Model: Print-Electronic

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Academic Journal

Development of a rapid and comprehensive genomic profiling test supporting diagnosis and research for gliomas.

  • Authors : Nakashima T; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-Ku, Tokyo, 104-0045, Japan.; Department of Neurosurgery, Nagoya University School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, 466-8550, Japan.

Subjects: Glioma*/Glioma*/Glioma*/genetics ; Glioma*/Glioma*/Glioma*/diagnosis ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/genetics

  • Source: Brain tumor pathology [Brain Tumor Pathol] 2024 Apr; Vol. 41 (2), pp. 50-60. Date of Electronic Publication: 2024 Feb 08.Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 9716507 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Adult epithelioid glioblastoma exhibits an extremely poor prognosis and high frequency of SWI/SNF complex mutation: Insights from a retrospective study.

  • Authors : Xi S; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, China.; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China.

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/mortality

  • Source: International journal of cancer [Int J Cancer] 2024 Jul 01; Vol. 155 (1), pp. 172-183. Date of Electronic Publication: 2024 Feb 27.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

AAV-mediated hepatic expression of SLC30A10 and the Thr95Ile variant attenuates manganese excess and other phenotypes in Slc30a10-deficient mice.

  • Authors : Prajapati M; Department of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.; Quenneville CB

Subjects: Cation Transport Proteins*/Cation Transport Proteins*/Cation Transport Proteins*/deficiency ; Cation Transport Proteins*/Cation Transport Proteins*/Cation Transport Proteins*/genetics ; Cation Transport Proteins*/Cation Transport Proteins*/Cation Transport Proteins*/metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Mar; Vol. 300 (3), pp. 105732. Date of Electronic Publication: 2024 Feb 08.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Update on quality assurance in neuropathology: Summary of the round robin trials on TERT promoter mutation, H3-3A mutation, 1p/19q codeletion, and KIAA1549::BRAF fusion testing in Germany in 2020 and 2021.

Subjects: Biomarkers, Tumor*/Biomarkers, Tumor*/Biomarkers, Tumor*/genetics ; Chromosome Deletion* ; Genetic Testing*

  • Source: Clinical neuropathology [Clin Neuropathol] 2023 May-Jun; Vol. 42 (3), pp. 112-121.Publisher: Dustri-Verlag Country of Publication: Germany NLM ID: 8214420 Publication Model: Print Cited Medium: Internet ISSN: 0722-5091 (Print)

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Academic Journal

High-resolution landscape of an antibiotic binding site.

  • Authors : Yang KB; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.; Cameranesi M

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/chemistry ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/metabolism ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology

  • Source: Nature [Nature] 2023 Oct; Vol. 622 (7981), pp. 180-187. Date of Electronic Publication: 2023 Aug 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.

  • Authors : Patel PS; Princess Margaret Cancer Centre, University Health Network, Toronto, OntarioM5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto, OntarioM5G 1L7, Canada.

Subjects: BRCA1 Protein*/BRCA1 Protein*/BRCA1 Protein*/deficiency ; BRCA1 Protein*/BRCA1 Protein*/BRCA1 Protein*/genetics ; DNA Replication*/DNA Replication*/DNA Replication*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 May 22; Vol. 51 (9), pp. 4341-4362.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  3,713 results for ""Promoter Regions, Genetic""