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Academic Journal

Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19.

  • Authors : Vilskersts R; Laboratory of Pharmaceutical Pharmacology, Latvian Institute of Organic Synthesis, LV-1006 Riga, Latvia.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Rigas Stradins University, LV-1007 Riga, Latvia.

Subjects: Cardiotonic Agents/Cardiotonic Agents/Cardiotonic Agents/*pharmacology ; Methylhydrazines/Methylhydrazines/Methylhydrazines/*pharmacology; Animals

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 21; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Carnitine and γ-Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2-mediated Transport.

Subjects: Betaine/Betaine/Betaine/*analogs & derivatives ; Carnitine/Carnitine/Carnitine/*administration & dosage ; Methylhydrazines/Methylhydrazines/Methylhydrazines/*pharmacokinetics

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2017 May; Vol. 120 (5), pp. 450-456. Date of Electronic Publication: 2017 Jan 10.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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Academic Journal

Pharmacological effects of meldonium: Biochemical mechanisms and biomarkers of cardiometabolic activity.

  • Authors : Dambrova M; Latvian Institute of Organic Synthesis, Aizkraukles Str. 21, Riga LV-1006, Latvia; Riga Stradins University, Dzirciema Str. 16, Riga LV-1007, Latvia. Electronic address: .

Subjects: Biomarkers/Biomarkers/Biomarkers/*metabolism ; Methylhydrazines/Methylhydrazines/Methylhydrazines/*pharmacology ; Methylhydrazines/Methylhydrazines/Methylhydrazines/*therapeutic use

  • Source: Pharmacological research [Pharmacol Res] 2016 Nov; Vol. 113 (Pt B), pp. 771-780. Date of Electronic Publication: 2016 Feb 02.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Editorial & Opinion

The unusual pharmacokinetics of meldonium: Implications for doping.

  • Authors : Liepinsh E; Latvian Institute of Organic Synthesis, Aizkraukles Str. 21, Riga, LV1006, Latvia.; Dambrova M

Subjects: Doping in Sports/Doping in Sports/Doping in Sports/*methods ; Methylhydrazines/Methylhydrazines/Methylhydrazines/*pharmacokinetics; Animals

  • Source: Pharmacological research [Pharmacol Res] 2016 Sep; Vol. 111, pp. 100. Date of Electronic Publication: 2016 Jun 02.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Carnitine congener mildronate protects against stress- and haloperidol-induced impairment in memory and brain protein expression in rats.

  • Authors : Beitnere U; Department of Pharmacology, Faculty of Medicine, University of Latvia, 19, Raina blv., Riga LV-1586, Latvia.; Dzirkale Z

Subjects: Brain/Brain/Brain/*drug effects ; Memory/Memory/Memory/*drug effects ; Methylhydrazines/Methylhydrazines/Methylhydrazines/*pharmacology

  • Source: European journal of pharmacology [Eur J Pharmacol] 2014 Dec 15; Vol. 745, pp. 76-83. Date of Electronic Publication: 2014 Oct 17.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.

  • Authors : Kuka J; Latvian Institute of Organic Synthesis, Aizkraukles Str. 21, Riga, LV-1006, Latvia. Electronic address: .; Liepinsh E

Subjects: Biosynthetic Pathways/Biosynthetic Pathways/Biosynthetic Pathways/*drug effects ; Carnitine/Carnitine/Carnitine/*metabolism ; Gastrointestinal Tract/Gastrointestinal Tract/Gastrointestinal Tract/*microbiology

  • Source: Life sciences [Life Sci] 2014 Nov 11; Vol. 117 (2), pp. 84-92. Date of Electronic Publication: 2014 Oct 07.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of experimental and sample factors on dehydration kinetics of mildronate dihydrate: mechanism of dehydration and determination of kinetic parameters.

Subjects: Cardiovascular Agents/Cardiovascular Agents/Cardiovascular Agents/*chemistry ; Methylhydrazines/Methylhydrazines/Methylhydrazines/*chemistry ; Water/Water/Water/*chemistry

  • Source: Journal of pharmaceutical sciences [J Pharm Sci] 2014 Jun; Vol. 103 (6), pp. 1747-55. Date of Electronic Publication: 2014 Apr 11.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mildronate improves cognition and reduces amyloid-β pathology in transgenic Alzheimer's disease mice.

  • Authors : Beitnere U; Department of Pharmacology, Faculty of Medicine, University of Latvia, Riga, Latvia.; van Groen T

Subjects: Adjuvants, Immunologic/Adjuvants, Immunologic/Adjuvants, Immunologic/*therapeutic use ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism

  • Source: Journal of neuroscience research [J Neurosci Res] 2014 Mar; Vol. 92 (3), pp. 338-46. Date of Electronic Publication: 2013 Nov 22.Publisher: Wiley Interscience Country of Publication: United States NLM ID: 7600111 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mildronate, the inhibitor of L-carnitine transport, induces brain mitochondrial uncoupling and protects against anoxia-reoxygenation.

  • Authors : Makrecka M; Latvian Institute of Organic Synthesis, Aizkraukles Str. 21, Riga LV-1006, Latvia; Riga Stradins University, Faculty of Pharmacy, Dzirciema Str. 16, Riga LV-1007, Latvia. Electronic address: .

Subjects: Brain/Brain/Brain/*drug effects ; Carnitine/Carnitine/Carnitine/*antagonists & inhibitors ; Methylhydrazines/Methylhydrazines/Methylhydrazines/*pharmacology

  • Source: European journal of pharmacology [Eur J Pharmacol] 2014 Jan 15; Vol. 723, pp. 55-61. Date of Electronic Publication: 2013 Dec 12.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Microencapsulation of mildronate in biodegradable and non-biodegradable polymers.

  • Authors : Loca D; Rudolfs Cimdins Riga Biomaterials Innovations and Development Centre of Riga Technical University , Pulka 3/3, LV-1007, Riga , Latvia .; Sevostjanovs E

Subjects: Cardiovascular Agents*/Cardiovascular Agents*/Cardiovascular Agents*/chemistry ; Cardiovascular Agents*/Cardiovascular Agents*/Cardiovascular Agents*/pharmacokinetics ; Cardiovascular Agents*/Cardiovascular Agents*/Cardiovascular Agents*/pharmacology

  • Source: Journal of microencapsulation [J Microencapsul] 2014; Vol. 31 (3), pp. 246-53. Date of Electronic Publication: 2013 Oct 14.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8500513 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  41 results for ""Latvia""