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Academic Journal

FLT3-selective PROTAC: Enhanced safety and increased synergy with Venetoclax in FLT3-ITD mutated acute myeloid leukemia.

  • Authors : Tan Y; Department of Hematology, Zhongnan Hospital, Wuhan University, Wuhan, 430071, China.; Xin L

Subjects: fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/genetics ; fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/antagonists & inhibitors ; fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/fms-Like Tyrosine Kinase 3*/metabolism

  • Source: Cancer letters [Cancer Lett] 2024 Jun 28; Vol. 592, pp. 216933. Date of Electronic Publication: 2024 May 04.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Detection of novel PPP1R1B::STARD3 fusion transcript in acute myeloid leukemia: a case report.

  • Authors : Firouzabadi ED; Stem Cell and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR), Mashhad, Razavi Khorasan, Iran.; Department of Biology, Faculty of Science, Hakim Sabzevar University, Sabzevar, Iran.

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/diagnosis; Humans

  • Source: Journal of medical case reports [J Med Case Rep] 2024 Jun 05; Vol. 18 (1), pp. 269. Date of Electronic Publication: 2024 Jun 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947

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Academic Journal

Raman spectroscopy can recognize the KMT2A rearrangement as a distinct subtype of leukemia.

  • Authors : Leszczenko P; Jagiellonian University, Faculty of Chemistry, Department of Chemical Physics, Gronostajowa 2, 30-387 Krakow, Poland; Jagiellonian University, Doctoral School of Exact and Natural Sciences, Lojasiewicza 11, 30-348 Krakow, Poland. Electronic address: .

Subjects: Myeloid-Lymphoid Leukemia Protein*/Myeloid-Lymphoid Leukemia Protein*/Myeloid-Lymphoid Leukemia Protein*/genetics ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/diagnosis ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics

  • Source: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2024 Jun 05; Vol. 314, pp. 124173. Date of Electronic Publication: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557

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Academic Journal

Preferential HDAC6 inhibitors derived from HPOB exhibit synergistic antileukemia activity in combination with decitabine.

  • Authors : Tretbar M; Institute for Drug Discovery, Medical Faculty, Leipzig University, Brüderstraße 34, 04103, Leipzig, Germany.; Schliehe-Diecks J

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemistry ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemical synthesis

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Jun 05; Vol. 272, pp. 116447. Date of Electronic Publication: 2024 Apr 26.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML.

  • Authors : Marchesini M; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Translational Hematology and Chemogenomics Laboratory, University of Parma, Parma, Italy.

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/metabolism

  • Source: Nature communications [Nat Commun] 2024 Jun 04; Vol. 15 (1), pp. 4739. Date of Electronic Publication: 2024 Jun 04.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

In silico predicted compound targeting the IQGAP1-GRD domain selectively inhibits growth of human acute myeloid leukemia.

  • Authors : Sahasrabudhe DM; Wilmot Cancer Institute, University of Rochester Medical Center, 601 Elmwood Avenue, Box 704, Rochester, NY, 14618, USA. .; Department of Medicine, Hematology/Oncology, University of Rochester Medical Center, Rochester, NY, USA. .

Subjects: ras GTPase-Activating Proteins*/ras GTPase-Activating Proteins*/ras GTPase-Activating Proteins*/metabolism ; ras GTPase-Activating Proteins*/ras GTPase-Activating Proteins*/ras GTPase-Activating Proteins*/genetics ; ras GTPase-Activating Proteins*/ras GTPase-Activating Proteins*/ras GTPase-Activating Proteins*/antagonists & inhibitors

  • Source: Scientific reports [Sci Rep] 2024 Jun 04; Vol. 14 (1), pp. 12868. Date of Electronic Publication: 2024 Jun 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.

  • Authors : Qiao X; Division of Tumor Biology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. .; Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands. .

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/drug therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/mortality ; Aclarubicin*/Aclarubicin*/Aclarubicin*/pharmacology

  • Source: Molecular cancer [Mol Cancer] 2024 Jun 04; Vol. 23 (1), pp. 120. Date of Electronic Publication: 2024 Jun 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Implementation of and Systems-Level Barriers to Guideline-Driven Germline Genetic Evaluation in the Care of Patients With Myelodysplastic Syndrome and Acute Myeloid Leukemia.

  • Authors : Banaszak LG; Department of Medicine, University of Wisconsin-Madison, Madison, WI.; Cabral PL

Subjects: Myelodysplastic Syndromes*/Myelodysplastic Syndromes*/Myelodysplastic Syndromes*/genetics ; Myelodysplastic Syndromes*/Myelodysplastic Syndromes*/Myelodysplastic Syndromes*/therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics

  • Source: JCO precision oncology [JCO Precis Oncol] 2024 Jun; Vol. 8, pp. e2300518.Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101705370 Publication Model: Print Cited Medium: Internet

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Academic Journal

Post-transplant de novo anti-HLA donor specific antibodies may contribute to poor graft function after haploidentical haematopoietic stem cell transplantation.

  • Authors : Ji X; Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China.

Subjects: Hematopoietic Stem Cell Transplantation*/Hematopoietic Stem Cell Transplantation*/Hematopoietic Stem Cell Transplantation*/methods ; HLA Antigens*/HLA Antigens*/HLA Antigens*/immunology ; Isoantibodies*/Isoantibodies*/Isoantibodies*/immunology

  • Source: HLA [HLA] 2024 Jun; Vol. 103 (6), pp. e15560.Publisher: Wiley Blackwell Country of Publication: England NLM ID: 101675570 Publication Model: Print Cited Medium: Internet ISSN: 2059-2310

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Academic Journal

Chimeric antigen receptor T-cell therapy in childhood acute myeloid leukemia: how far are we from a clinical application?

  • Authors : Naik S; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN, USA.; Velasquez MP

Subjects: Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/therapy ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/immunology ; Receptors, Chimeric Antigen*/Receptors, Chimeric Antigen*/Receptors, Chimeric Antigen*/immunology

  • Source: Haematologica [Haematologica] 2024 Jun 01; Vol. 109 (6), pp. 1656-1667. Date of Electronic Publication: 2024 Jun 01.Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  83,793 results for ""Leukemia, Myeloid, Acute""