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Academic Journal

The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes.

  • Authors : Pemberton JM; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Canada.; Biological Sciences Platform, Sunnybrook Research Institute, Toronto, Canada.

Subjects: Apoptosis Regulatory Proteins*/Apoptosis Regulatory Proteins*/Apoptosis Regulatory Proteins*/metabolism ; Neoplasms*; Humans

  • Source: ELife [Elife] 2023 Apr 20; Vol. 12. Date of Electronic Publication: 2023 Apr 20.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins.

  • Authors : van Leeuwen JE; Department of Medical Biophysics, University of Toronto, 101 College Street, Toronto, ON, M5G 1L7, Canada.; Princess Margaret Cancer Centre, University Health Network, 101 College Street, Toronto, ON, M5G 1L7, Canada.

Subjects: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/drug therapy

  • Source: Nature communications [Nat Commun] 2022 Oct 24; Vol. 13 (1), pp. 6323. Date of Electronic Publication: 2022 Oct 24.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells.

  • Authors : Saraon P; Drug Discovery Program, Ontario Institute for Cancer Research, Ontario, Canada. Electronic address: .; Snider J

Subjects: Drug Discovery*/Drug Discovery*/Drug Discovery*/methods; Coatomer Protein/Coatomer Protein/Coatomer Protein/*genetics ; Coatomer Protein/Coatomer Protein/Coatomer Protein/*metabolism

  • Source: Journal of molecular biology [J Mol Biol] 2021 Nov 19; Vol. 433 (23), pp. 167294. Date of Electronic Publication: 2021 Oct 16.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A reference library for assigning protein subcellular localizations by image-based machine learning.

Subjects: Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism ; Green Fluorescent Proteins/Green Fluorescent Proteins/Green Fluorescent Proteins/*metabolism ; Image Processing, Computer-Assisted/Image Processing, Computer-Assisted/Image Processing, Computer-Assisted/*standards

  • Source: The Journal of cell biology [J Cell Biol] 2020 Mar 02; Vol. 219 (3).Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Genome-wide analysis of Homo sapiens, Arabidopsis thaliana, and Saccharomyces cerevisiae reveals novel attributes of tail-anchored membrane proteins.

  • Authors : Brito GC; Biological Sciences, Sunnybrook Research Institute, Toronto, ON, M4N 3M5, Canada.; Schormann W

Subjects: Arabidopsis Proteins/Arabidopsis Proteins/Arabidopsis Proteins/*chemistry ; Arabidopsis Proteins/Arabidopsis Proteins/Arabidopsis Proteins/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*chemistry

  • Source: BMC genomics [BMC Genomics] 2019 Nov 11; Vol. 20 (1), pp. 835. Date of Electronic Publication: 2019 Nov 11.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Activated ErbB3 Translocates to the Nucleus via Clathrin-independent Endocytosis, Which Is Associated with Proliferating Cells.

  • Authors : Reif R; From the Leibniz Research Centre for Working Environment and Human Factors, 44139 Dortmund, Germany, .; Adawy A

Subjects: Cell Proliferation/Cell Proliferation/Cell Proliferation/*physiology ; Clathrin/Clathrin/Clathrin/*metabolism ; Endocytosis/Endocytosis/Endocytosis/*physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2016 Feb 19; Vol. 291 (8), pp. 3837-47. Date of Electronic Publication: 2015 Dec 30.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits.

  • Authors : Hardelauf H; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Otto-Hahn-Str. 6b, 44227, Dortmund, Germany.; Frimat JP

Subjects: Spheroids, Cellular*; Colonic Neoplasms/Colonic Neoplasms/Colonic Neoplasms/*metabolism ; Microarray Analysis/Microarray Analysis/Microarray Analysis/*methods

  • Source: Lab on a chip [Lab Chip] 2011 Feb 07; Vol. 11 (3), pp. 419-28. Date of Electronic Publication: 2010 Nov 16.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101128948 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Ep-CAM RNA expression predicts metastasis-free survival in three cohorts of untreated node-negative breast cancer.

  • Authors : Schmidt M; Department of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg-University, Langenbeckstr. 1, 55131, Mainz, Germany. ; Petry IB

Subjects: Gene Expression Regulation, Neoplastic*; Antigens, Neoplasm/Antigens, Neoplasm/Antigens, Neoplasm/*genetics ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics

  • Source: Breast cancer research and treatment [Breast Cancer Res Treat] 2011 Feb; Vol. 125 (3), pp. 637-46. Date of Electronic Publication: 2010 Mar 30.Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes.

  • Authors : Zellmer S; Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany. ; Schmidt-Heck W

Subjects: Cell Proliferation*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*physiology ; E2F1 Transcription Factor/E2F1 Transcription Factor/E2F1 Transcription Factor/*physiology

  • Source: Hepatology (Baltimore, Md.) [Hepatology] 2010 Dec; Vol. 52 (6), pp. 2127-36. Date of Electronic Publication: 2010 Oct 26.Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration.

  • Authors : Hoehme S; Interdisciplinary Centre for Bioinformatics (IZBI), University of Leipzig, Härtelstrasse 16-18, D-04107 Leipzig, Germany.; Brulport M

Subjects: Cell Movement* ; Liver Regeneration* ; Models, Biological*

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2010 Jun 08; Vol. 107 (23), pp. 10371-6. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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