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Structural and Computational Insights into Dynamics and Intermediate States of Orexin 2 Receptor Signaling.

• Authors : Yokoi S; Department of Physics, School of Science and Technology, Meiji University, 1-1-1 Higashi-Mita, Tama-ku, Kawasaki, Kanagawa 214-8571, Japan.; Suno R

• Source: The journal of physical chemistry. B [J Phys Chem B] 2024 May 09. Date of Electronic Publication: 2024 May 09.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet

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Exploring Diverse Signaling Mechanisms of G Protein-Coupled Receptors through Structural Biology.

• Authors : Suno R; Department of Medical Chemistry, Kansai Medical University, Hirakata, 573-1010, Japan.

Subjects: Receptors, G-Protein-Coupled*/Receptors, G-Protein-Coupled*/Receptors, G-Protein-Coupled*/metabolism ; Signal Transduction*; GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/metabolism

• Source: Journal of biochemistry [J Biochem] 2024 Mar 25; Vol. 175 (4), pp. 357-365.Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print Cited Medium: Internet ISSN:

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Interaction modes of human orexin 2 receptor with selective and nonselective antagonists studied by NMR spectroscopy.

• Authors : Imamura K; Department of Biophysics, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.; Akagi KI

Subjects: Methionine*; Humans ; Orexins

• Source: Structure (London, England : 1993) [Structure] 2024 Mar 07; Vol. 32 (3), pp. 352-361.e5. Date of Electronic Publication: 2024 Jan 08.Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor.

• Authors : Asada H; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan. Electronic address: .; Im D

Subjects: Pyridines* ; Drug Design*; Orexins

• Source: Structure (London, England : 1993) [Structure] 2022 Dec 01; Vol. 30 (12), pp. 1582-1589.e4. Date of Electronic Publication: 2022 Nov 22.Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Structural insights into the G protein selectivity revealed by the human EP3-G i signaling complex.

• Authors : Suno R; Department of Medical Chemistry, Kansai Medical University, Hirakata 573-1010, Japan. Electronic address: .; Sugita Y

Subjects: Dinoprostone*/Dinoprostone*/Dinoprostone*/pharmacology ; Receptors, Prostaglandin E*/Receptors, Prostaglandin E*/Receptors, Prostaglandin E*/agonists ; Receptors, Prostaglandin E*/Receptors, Prostaglandin E*/Receptors, Prostaglandin E*/metabolism

• Source: Cell reports [Cell Rep] 2022 Sep 13; Vol. 40 (11), pp. 111323.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247

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A Liquid Chromatography-Mass Spectrometry Method to Study the Interaction between Membrane Proteins and Low-Molecular-Weight Compound Mixtures.

• Authors : Ogiso H; Toyama Prefectural Institute for Pharmaceutical Research, Imizu 939-0363, Toyama, Japan.; Suno R

Subjects: Membrane Proteins*; Chromatography, Gel ; Chromatography, Liquid/Chromatography, Liquid/Chromatography, Liquid/methods

• Source: Molecules (Basel, Switzerland) [Molecules] 2022 Jul 30; Vol. 27 (15). Date of Electronic Publication: 2022 Jul 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Vibrational spectroscopy analysis of ligand efficacy in human M 2 muscarinic acetylcholine receptor (M 2 R).

• Authors : Katayama K; Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, Showa-ku, Nagoya, 466-8555, Japan. .; OptoBioTechnology Research Center, Nagoya Institute of Technology, Showa-ku, Nagoya, 466-8555, Japan. .

Subjects: Receptor, Muscarinic M2/Receptor, Muscarinic M2/Receptor, Muscarinic M2/*chemistry; Humans ; Ligands

• Source: Communications biology [Commun Biol] 2021 Nov 23; Vol. 4 (1), pp. 1321. Date of Electronic Publication: 2021 Nov 23.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Cryo-EM structure of the human MT 1 -G i signaling complex.

• Authors : Okamoto HH; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.; Miyauchi H

Subjects: GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/*metabolism ; Melatonin/Melatonin/Melatonin/*metabolism ; Receptor, Melatonin, MT1/Receptor, Melatonin, MT1/Receptor, Melatonin, MT1/*metabolism

• Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2021 Aug; Vol. 28 (8), pp. 694-701. Date of Electronic Publication: 2021 Aug 05.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Vibrational analysis of acetylcholine binding to the M 2 receptor.

• Authors : Suzuki K; Department of Life Science and Applied Chemistry, Nagoya Institute of Technology Showa-ku Nagoya 466-8555 Japan .; Katayama K

• Source: RSC advances [RSC Adv] 2021 Apr 07; Vol. 11 (21), pp. 12559-12567. Date of Electronic Publication: 2021 Apr 07 (Print Publication: 2021).Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN:

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Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein.

• Authors : Nojima S; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto 606-8501, Japan.; Fujita Y

Subjects: GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/*chemistry ; Receptors, Prostaglandin E, EP4 Subtype/Receptors, Prostaglandin E, EP4 Subtype/Receptors, Prostaglandin E, EP4 Subtype/*chemistry; Animals

• Source: Structure (London, England : 1993) [Structure] 2021 Mar 04; Vol. 29 (3), pp. 252-260.e6. Date of Electronic Publication: 2020 Dec 01.Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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