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Academic Journal

Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation.

  • Authors : Zhu Y; State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China.; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China.

Subjects: ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/metabolism ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/genetics ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/antagonists & inhibitors

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 May 09; Vol. 67 (9), pp. 7283-7300. Date of Electronic Publication: 2024 Apr 27.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

BRAF V600E mutation does not predict lymph node metastases and recurrence in Chinese papillary thyroid microcarcinoma patients.

  • Authors : Zhao H; Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100010, China; Surgery Centre of Diabetes Mellitus, Beijing Shijitan Hospital, Capital Medical University, Beijing 100036, China. Electronic address: .

Subjects: Thyroid Neoplasms*/Thyroid Neoplasms*/Thyroid Neoplasms*/genetics ; Thyroid Neoplasms*/Thyroid Neoplasms*/Thyroid Neoplasms*/pathology ; Thyroid Neoplasms*/Thyroid Neoplasms*/Thyroid Neoplasms*/therapy Papillary Thyroid Microcarcinoma

  • Source: Oral oncology [Oral Oncol] 2024 May; Vol. 152, pp. 106755. Date of Electronic Publication: 2024 Mar 28.Publisher: Elsevier Country of Publication: England NLM ID: 9709118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0593

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Academic Journal

Infectivity versus fatality of SARS-CoV-2 mutations and influenza.

  • Authors : Xue L; College of Mathematical Sciences, Harbin Engineering University, Harbin, Heilongjiang, 150001, China.; Jing S

Subjects: COVID-19*/COVID-19*/COVID-19*/epidemiology ; COVID-19*/COVID-19*/COVID-19*/virology ; Influenza A Virus, H1N1 Subtype*/Influenza A Virus, H1N1 Subtype*/Influenza A Virus, H1N1 Subtype*/genetics SARS-CoV-2 variants

  • Source: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2022 Aug; Vol. 121, pp. 195-202. DatePublisher: Elsevier Country of Publication: Canada NLM ID: 9610933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3511

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Academic Journal

Targeted therapy with anlotinib for a H3K27M mutation diffuse midline glioma patient with PDGFR-α mutation: a case report.

  • Authors : Wang Q; Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, 305 East Zhongshan Road, Nanjing, 210002, Jiangsu, China.; Niu W

Subjects: Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/drug therapy ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/genetics ; Glioma*/Glioma*/Glioma*/drug therapy

  • Source: Acta neurochirurgica [Acta Neurochir (Wien)] 2022 Aug; Vol. 164 (8), pp. 2063-2066. Date of Electronic Publication: 2021 Nov 23.Publisher: Springer Country of Publication: Austria NLM ID: 0151000 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0942-0940

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Academic Journal

Mitochondrial base editor induces substantial nuclear off-target mutations.

  • Authors : Lei Z; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.

Subjects: Cell Nucleus*/Cell Nucleus*/Cell Nucleus*/genetics ; Cytosine*/Cytosine*/Cytosine*/metabolism ; Gene Editing*

  • Source: Nature [Nature] 2022 Jun; Vol. 606 (7915), pp. 804-811. Date of Electronic Publication: 2022 May 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Diverse kinase alterations and myeloid-associated mutations in adult histiocytosis.

  • Authors : Chen J; Department of Hematology, Peking Union Medical Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.; Zhao AL

Subjects: Mutation*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*genetics ; Histiocytosis/Histiocytosis/Histiocytosis/*pathology

  • Source: Leukemia [Leukemia] 2022 Feb; Vol. 36 (2), pp. 573-576. Date of Electronic Publication: 2021 Oct 05.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo.

  • Authors : Liu Y; Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China.; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use

  • Source: Cancer science [Cancer Sci] 2022 Feb; Vol. 113 (2), pp. 709-720. Date of Electronic Publication: 2021 Dec 16.Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic

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Academic Journal

Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy.

  • Authors : Zhu M; Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.

Subjects: Biomarkers, Tumor* ; Mutation*; Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*diagnosis

  • Source: Frontiers in immunology [Front Immunol] 2022 Jan 06; Vol. 12, pp. 800951. Date of Electronic Publication: 2022 Jan 06 (Print Publication: 2021).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Report

Novel bi-allelic HPDL variants cause hereditary spastic paraplegia in a Chinese patient.

  • Authors : Yu H; Department of Neurology and Research Center of Neurology in Second Affiliated Hospital, and Key Laboratory of Medical Neurobiology of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou, China.; Wei Q

Subjects: Alleles* ; Genetic Association Studies*/Genetic Association Studies*/Genetic Association Studies*/methods ; Genetic Predisposition to Disease*

  • Source: Clinical genetics [Clin Genet] 2021 Dec; Vol. 100 (6), pp. 777-778. Date of Electronic Publication: 2021 Sep 13.Publisher: Munksgaard Country of Publication: Denmark NLM ID: 0253664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0004

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Academic Journal

A comprehensive genome-wide analysis of long non-coding RNA and mRNA expression profiles of JAK2V617F-positive classical myeloproliferative neoplasms.

  • Authors : Zhou J; Tongji University School of Medicine, Shanghai, 200092, China.; Department of Gastroenterology, Tongji Hospital of Tongji University, Shanghai, 200065, China.

Subjects: Gene Expression Profiling* ; Gene Expression Regulation, Neoplastic* ; Genome, Human*

  • Source: Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (2), pp. 10564-10586.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101581063 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  341 results for ""Hao H""