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Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.

• Authors : Gorman J; Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.; Mason RD

Subjects: Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*chemistry ; Antibodies, Neutralizing/Antibodies, Neutralizing/Antibodies, Neutralizing/*chemistry ; HIV/HIV/HIV/*physiology

• Source: Immunity [Immunity] 2019 Oct 15; Vol. 51 (4), pp. 724-734.e4. Date of Electronic Publication: 2019 Oct 02.Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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A high throughput lentivirus sieving assay identifies neutralization resistant Envelope sequences and predicts in vivo sieving.

• Authors : Iwamoto N; ImmunoTechnology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, United States.; Mason R

Subjects: Gene Products, env* ; High-Throughput Nucleotide Sequencing* ; Immunogenicity, Vaccine*

• Source: Journal of immunological methods [J Immunol Methods] 2019 Jan; Vol. 464, pp. 64-73. Date of Electronic Publication: 2018 Oct 31.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1305440 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Therapeutic vaccination expands and improves the function of the HIV-specific memory T-cell repertoire.

• Authors : Casazza JP; Bowman KA ...

Subjects: AIDS Vaccines/AIDS Vaccines/AIDS Vaccines/*immunology ; CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/*immunology ; HIV/HIV/HIV/*immunology

• Source: The Journal of infectious diseases [J Infect Dis] 2013 Jun 15; Vol. 207 (12), pp. 1829-40. Date of Electronic Publication: 2013 Mar 12.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print-Electronic Cited Medium: Internet

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Estimating the impact of vaccination on acute simian-human immunodeficiency virus/simian immunodeficiency virus infections.

• Authors : Petravic J; Complex Systems in Biology Group, Centre for Vascular Research, University of New South Wales 2052, New South Wales, Australia.; Ribeiro RM

Subjects: HIV/HIV/HIV/*immunology ; SAIDS Vaccines/SAIDS Vaccines/SAIDS Vaccines/*immunology ; Simian Acquired Immunodeficiency Syndrome/Simian Acquired Immunodeficiency Syndrome/Simian Acquired Immunodeficiency Syndrome/*prevention & control

• Source: Journal of virology [J Virol] 2008 Dec; Vol. 82 (23), pp. 11589-98. Date of Electronic Publication: 2008 Sep 17.Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium:

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Early and Long-Term HIV-1 Immunogenicity Induced in Macaques by the Combined Administration of DNA, NYVAC and Env Protein-Based Vaccine Candidates: The AUP512 Study.

• Authors : Perdiguero, Beatriz; Asbach, Benedikt; Gómez, Carmen E.

Subjects: IMMUNE response; HIV; MACAQUES

• Source: Frontiers in Immunology; 7/22/2022, Vol. 13, p1-20, 20p

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The V2 loop of HIV gp120 delivers costimulatory signals to CD4+ T cells through Integrin α4β7 and promotes cellular activation and infection.

• Authors : Goes, Livia R.; Sajani, Alia; Sivro, Aida

Subjects: T cells; HIV infections; INTEGRINS

• Source: Proceedings of the National Academy of Sciences of the United States of America; 12/22/2020, Vol. 117 Issue 51, p32566-32573, 8p

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Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.

• Authors : Roederer, Mario; Keele, Brandon F.; Schmidt, Stephen D.

Subjects: IMMUNOLOGY; VIROLOGY; SIMIAN immunodeficiency virus diseases

• Source: Nature. 1/23/2014, Vol. 505 Issue 7484, p502-508. 7p.

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Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge.

• Authors : Welles, Hugh C.; Jennewein, Madeleine F.; Mason, Rosemarie D.

Subjects: ADENO-associated virus; GENE delivery techniques; IMMUNOGLOBULINS

• Source: PLoS Pathogens; 12/5/2018, Vol. 14 Issue 12, p1-28, 28p

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Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells.

• Authors : Bolton, Diane L.; McGinnis, Kathleen; Finak, Greg

Subjects: CD4 antigen; T cells; FLOW cytometry

• Source: PLoS Pathogens; 6/27/2017, Vol. 13 Issue 6, p1-19, 19p

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Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques.

• Authors : Zurawski, Gerard; Zurawski, Sandra; Flamar, Anne-Laure

Subjects: AIDS vaccines; GLYCOPROTEINS; RHESUS monkeys

• Source: PLoS ONE; 4/14/2016, Vol. 11 Issue 4, p1-23, 23p

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Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability.

• Authors : Mason, Rosemarie D.; Welles, Hugh C.; Adams, Cameron

Subjects: VIRUS isolation; SIMIAN immunodeficiency virus diseases; SIMIAN immunodeficiency virus

• Source: PLoS Pathogens; 4/11/2016, Vol. 12 Issue 4, p1-33, 33p

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Homologous Boosting with Adenoviral Serotype 5 HIV Vaccine (rAd5) Vector Can Boost Antibody Responses despite Preexisting Vector-Specific Immunity in a Randomized Phase I Clinical Trial.

• Authors : Sarwar, Uzma N.; Novik, Laura; Enama, Mary E.

Subjects: AIDS vaccines; ADENOVIRUSES; HIV prevention

• Source: PLoS ONE; Sep2014, Vol. 9 Issue 9, p1-10, 10p

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Phase I Randomized Clinical Trial of VRC DNA and rAd5 HIV-1 Vaccine Delivery by Intramuscular (IM), Subcutaneous (SC) and Intradermal (ID) Administration (VRC 011).

• Authors : Enama, Mary E.; Ledgerwood, Julie E.; Novik, Laura

Subjects: CLINICAL trials; VIRAL vaccines; DRUG administration

• Source: PLoS ONE; Mar2014, Vol. 9 Issue 3, p1-11, 11p

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A Conversation with Leonard and Leonore Herzenberg.

• Authors : Herzenberg, Leonard A.; Herzenberg, Leonore A.; Roederer, Mario

Subjects: FLOW cytometry; HYBRIDOMAS; IMMUNOLOGY

• Source: Annual Review of Physiology; 2014, Vol. 76, p1-20, 16p

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Loss of Circulating CD4 T Cells with B Cell Helper Function during Chronic HIV Infection.

• Authors : Boswell, Kristin L.; Paris, Robert; Boritz, Eli

Subjects: T cells; LYMPHOCYTES; B cells

• Source: PLoS Pathogens; Jan2014, Vol. 10 Issue 1, p1-14, 14p

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Mixture models for single-cell assays with applications to vaccine studies.

• Authors : Finak, Greg; McDavid, Andrew; Chattopadhyay, Pratip

Subjects: CYTOLOGY; IMMUNOLOGY; BIOLOGICAL assay

• Source: Biostatistics; Jan2014, Vol. 15 Issue 1, p87-101, 15p

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DNA Vaccine Delivered by a Needle-Free Injection Device Improves Potency of Priming for Antibody and CD8+ T-Cell Responses after rAd5 Boost in a Randomized Clinical Trial.

• Authors : Graham, Barney S.; Enama, Mary E.; Nason, Martha C.

Subjects: DNA vaccines; DRUG synergism; IMMUNOGLOBULINS

• Source: PLoS ONE; Apr2013, Vol. 8 Issue 4, p1-11, 11p

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Early immunologic correlates of HIV protection can be identified from computational analysis of complex multivariate T-cell flow cytometry assays*.

• Authors : Aghaeepour, Nima; Chattopadhyay, Pratip K.; Ganesan, Anuradha

Subjects: HIV prevention; COMPUTATIONAL biology; T cellsBIOCONDUCTOR (Computer software)

• Source: Bioinformatics; Apr2012, Vol. 28 Issue 7, p1009-1016, 8p

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Genetic immunization in the lung induces potent local and systemic immune responses.

• Authors : Kaimei Song; Bolton, Diane L.; WiIson, Robert L.

Subjects: RESPIRATORY infections; IMMUNE response; IMMUNOLOGY

• Source: Proceedings of the National Academy of Sciences of the United States of America; 12/21/2010, Vol. 107 Issue 51, p22213-22218, 6p, 1 Chart, 4 Graphs

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High frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections.

• Authors : Nishimura, Yoshiaki; Sadjadpour, Reza; Mattapallil, Joseph J.

Subjects: CD4 antigen; T cells; RHESUS monkeys

• Source: Proceedings of the National Academy of Sciences of the United States of America; 5/12/2009, Vol. 106 Issue 19, p8015-8020, 6p, 1 Chart, 4 Graphs

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Emerging Concepts in the Immunopathogenesis of AIDS.

• Authors : Douek, Daniel C.; Roederer, Mario; Koup, Richard A.

Subjects: AIDS; HIV; IMMUNE system

• Source: Annual Review of Medicine; 2009, Vol. 60 Issue 1, p471-484, 14p, 3 Diagrams

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T-cell quality in memory and protection: implications for vaccine design.

• Authors : Seder, Robert A.; Darrah, Patricia A.; Roederer, Mario

Subjects: T cells; FLOW cytometry; LYMPHOCYTES

• Source: Nature Reviews Immunology; Apr2008, Vol. 8 Issue 4, p247-258, 12p, 1 Diagram, 1 Chart, 4 Graphs

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Phase 1 Safety and Immunogenicity Evaluation of a Multiclade HIV-1 Candidate Vaccine Delivered by a Replication-Defective Recombinant Adenovirus Vector.

• Authors : Catanzaro, Andrew T.; Koup, Richard A.; Roederer, Mario

Subjects: HIV; VIRAL vaccines; PLASMIDS

• Source: Journal of Infectious Diseases; 12/15/2006, Vol. 194 Issue 12, p1638-1649, 12p

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Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge.

• Authors : Mattapallil, Joseph J.; Douek, Daniel C.; Buckler-White, Alicia

Subjects: SIMIAN viruses; HIV; CD4 antigen

• Source: Journal of Experimental Medicine; 6/12/2006, Vol. 203 Issue 6, p1533-1541, 9p

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Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates.

• Authors : Wille-Reece, Ulrike; Flynn, Barbara J.; Loré, Karin

Subjects: T cells; IMMUNIZATION; PRIMATES

• Source: Journal of Experimental Medicine; 5/15/2006, Vol. 203 Issue 5, p1249-1258, 10p

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Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses.

• Authors : Price, David A.; Brenchley, Jason M.; Ruff, Laura E.

Subjects: CYTOMEGALOVIRUSES; EPSTEIN-Barr virus; DNA viruses

• Source: Journal of Experimental Medicine; 11/21/2005, Vol. 202 Issue 10, p1349-1361, 13p

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Resting naïve CD4+ T cells massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques.

• Authors : Nishimura, Yoshiaki; Brown, Charles R.; Mattapallil, Joseph J.

Subjects: HIV; IMMUNODEFICIENCY; LYMPHOCYTES

• Source: Proceedings of the National Academy of Sciences of the United States of America; 5/31/2005, Vol. 102 Issue 22, p8000-8005, 6p

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Naive CD4 T cells inhibit CD28-costimulated R5 HIV replication in memory CD4 T cells.

• Authors : Mengozzi, Manuela; Malipatlolla, Meena; De Rosa, Stephen C.

Subjects: T cells; HIV; VIRAL replication

• Source: Proceedings of the National Academy of Sciences of the United States of America; 9/25/2001, Vol. 98 Issue 20, p11644, 6p, 3 Diagrams, 24 Graphs

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Antibody Fab‐Fc properties outperform titer in predictive models of SIV vaccine‐induced protection.

• Authors : Pittala, Srivamshi; Bagley, Kenneth; Schwartz, Jennifer A

Subjects: NATURAL immunity; BIOLOGICAL tags; SEROLOGY

• Source: Molecular Systems Biology; May2019, Vol. 15 Issue 5, pN.PAG-N.PAG, 1p

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OMIP-005: Quality and phenotype of antigen-responsive rhesus macaque T cells.

• Authors : Foulds, Kathryn E.; Donaldson, Mitzi; Roederer, Mario

• Source: Cytometry. Part A; May2012, Vol. 81A Issue 5, p360-361, 2p

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OMIP-009: Characterization of antigen-specific human T-cells.

• Authors : Lamoreaux, Laurie; Koup, Richard A.; Roederer, Mario

• Source: Cytometry. Part A; May2012, Vol. 81A Issue 5, p362-363, 2p

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Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine

• Authors : Catanzaro, Andrew T.¹; Roederer, Mario¹; Koup, Richard A.¹

Subjects: *DNA vaccines; *HIV; *T cells

• Source: Vaccine. May2007, Vol. 25 Issue 20, p4085-4092. 8p.

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152: CD8 T cell responses correlate with antigen but are independent of type I IFN and STING signaling after adenoviral vaccination.

• Authors : Quinn, Kylie¹; Zak, Daniel²; Costa, Andreia³

Subjects: *CD8 antigen; *T cells; *IMMUNOLOGY

• Source: Cytokine. Nov2014, Vol. 70 Issue 1, p64-65. 2p.

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Expression of CD40L by the ALVAC-Simian Immunodeficiency Virus Vector Abrogates T Cell Responses in Macaques.

• Authors : de Castro, Isabela Silva¹; Gordon, Shari N.¹; Jun Liu^2,3

Subjects: *T cells; *MACAQUES; *SIMIAN immunodeficiency virus

• Source: Journal of Virology. Mar2020, Vol. 94 Issue 6, p1-20. 20p.

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Early treatment with reverse transcriptase inhibitors significantly suppresses peak plasma IFNα in vivo during acute simian immunodeficiency virus infection.

• Authors : George, Jeffy¹; Renn, Lynnsey²; Verthelyi, Daniela³

Subjects: *SIMIAN immunodeficiency virus diseases; *REVERSE transcriptase inhibitors; *INTERFERONS

• Source: Cellular Immunology. Dec2016, Vol. 310, p156-164. 9p.

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Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses.

• Authors : Zurawski, Gerard^1,2,3; Xiaoying Shen⁴; Sandra Zurawski^1,2,3

Subjects: *CD40 antigen; *T cells; *HIV

• Source: Journal of Virology. May2017, Vol. 91 Issue 9, p1-20. 20p.

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Differential Impact of Magnitude, Polyfunctional Capacity, and Specificity of HIV-Specific CD8+ T Cell Responses on HIV Set Point.

• Authors : Riou, Catherine¹; Burgers, Wendy A.¹ ; Mlisana, Koleka^2,3

Subjects: *HIV; *HIV infection risk factors; *HIV infection transmission

• Source: Journal of Virology. Feb2014, Vol. 88 Issue 3, p1819-1824. 6p.

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Replication-Defective Adenovirus Vectors with Multiple Deletions Do Not Induce Measurable Vector-Specific T Cells in Human Trials.

• Authors : Koup, Richard A.^1,2 ; Lamoreaux, Laurie²; Zarkowsky, David²

Subjects: *ADENOVIRUSES; *DNA viruses; *T cells

• Source: Journal of Virology. Jun2009, Vol. 83 Issue 12, p6318-6322. 5p.

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Reduced Protection from Simian Immunodeficiency Virus SIVmac251 Infection Afforded by Memory CD8+ T Cells Induced by Vaccination during CD4+ T-Cell Deficiency.

• Authors : Vaccari, Monica¹; Mattapallil, Joseph²; Kaimei Song³

Subjects: *T cells; *HIV; *SIMIAN viruses

• Source: Journal of Virology. Oct2008, Vol. 82 Issue 19, p9629-9638. 10p.

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Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer

• Authors : Kern, Florian¹ ; LiPira, Giuseppina²; Gratama, Jan W.³

Subjects: *IMMUNE response; *ANTIGEN-antibody reactions; *CELLULAR immunity

• Source: Trends in Immunology. Sep2005, Vol. 26 Issue 9, p477-484. 8p.

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T-Cell Subsets That Harbor Human Immunodeficiency Virus (HIV) In Vivo: Implications for HIV Pathogenesis.

• Authors : Brenchley, Jason M.¹; Hill, Brenna J.¹; Ambrozak, David R.²

Subjects: *HIV; *HIV infections; *T cells

• Source: Journal of Virology. Feb2004, Vol. 78 Issue 3, p1160-1168. 9p. 2 Diagrams, 2 Charts, 16 Graphs.

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Differential Specificity and Immunogenicity of Adenovirus Type 5 Neutralizing Antibodies Elicited by Natural Infection or Immunization.

• Authors : Cheng Cheng¹; Gall, Jason G. D.²; Nason, Martha¹

Subjects: *ADENOVIRUSES; *INFECTION; *IMMUNIZATION

• Source: Journal of Virology. Jan2010, Vol. 84 Issue 1, p40-40. 1p.

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Estimating the Infectivity of CCR5-Tropic Simian Immunodeficiency Virus SIVmac251 in the Gut.

• Authors : Wilson, David P.^1,2; Mattapallil, Joseph J.³; Lay, Matthew D. H.¹

Subjects: *HIV; *HIV infections; *T cells

• Source: Journal of Virology. Aug2007, Vol. 81 Issue 15, p38-38. 1p.

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