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Academic Journal

ZAP facilitates NLRP3 inflammasome activation via promoting the oligomerization of NLRP3.

  • Authors : Qin D; Key Laboratory for Experimental Teratology of the Chinese Ministry of Education, and Key Laboratory of Infection and Immunity of Shandong Province, School of Basic Medical Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China; Department of Pathogenic Biology, School of Basic Medical Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.

Subjects: NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/genetics ; Inflammasomes*/Inflammasomes*/Inflammasomes*/metabolism

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 May 30; Vol. 133, pp. 112123. Date of Electronic Publication: 2024 Apr 25.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis.

  • Authors : Wei J; Department of Laboratory Medicine, Nanjing First Hospital, Nanjng Medical University, Nanjing 210006, China.; Peng MY

Subjects: NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/genetics ; Pyroptosis*

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 May 30; Vol. 133, pp. 112096. Date of Electronic Publication: 2024 Apr 23.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A potential virulence factor: Brucella flagellin FliK does not affect the main biological properties but inhibits the inflammatory response in RAW264.7 cells.

  • Authors : Zhai Y; College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China; Key Laboratory of Animal Biotechnology of the Ministry of Agriculture, Northwest A&F University, Yangling 712100, China.

Subjects: Flagellin*/Flagellin*/Flagellin*/metabolism ; Virulence Factors*/Virulence Factors*/Virulence Factors*/metabolism ; Virulence Factors*/Virulence Factors*/Virulence Factors*/genetics

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 May 30; Vol. 133, pp. 112119. Date of Electronic Publication: 2024 Apr 21.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tranilast alleviates visceral hypersensitivity and colonic hyperpermeability by suppressing NLRP3 inflammasome activation in irritable bowel syndrome rat models.

  • Authors : Nozu T; Department of Regional Medicine and Education, Asahikawa Medical University, 2-1-1-1 Midorigaoka-Higashi, Asahikawa, Hokkaido 078-8510, Japan; Center for Medical Education, Asahikawa Medical University, 2-1-1-1 Midorigaoka-Higashi, Asahikawa, Hokkaido 078-8510, Japan

Subjects: NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/antagonists & inhibitors ; Irritable Bowel Syndrome*/Irritable Bowel Syndrome*/Irritable Bowel Syndrome*/drug therapy

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 May 30; Vol. 133, pp. 112099. Date of Electronic Publication: 2024 Apr 20.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exosomal long non-coding RNA AU020206 alleviates macrophage pyroptosis in atherosclerosis by suppressing CEBPB-mediated NLRP3 transcription.

  • Authors : Zhang N; Department of Vascular Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, PR China.; Luo Y

Subjects: Pyroptosis*/Pyroptosis*/Pyroptosis*/drug effects ; Pyroptosis*/Pyroptosis*/Pyroptosis*/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism

  • Source: Experimental cell research [Exp Cell Res] 2024 May 15; Vol. 438 (2), pp. 114054. Date of Electronic Publication: 2024 Apr 23.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Emodin relieves morphine-stimulated BV2 microglial activation and inflammation through the TLR4/NF-κB/NLRP3 pathway.

  • Authors : Li S; Department of Anesthesiology, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou Province, China.; Tang S

Subjects: Emodin*/Emodin*/Emodin*/pharmacology ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/drug effects

  • Source: Neuroreport [Neuroreport] 2024 May 15; Vol. 35 (8), pp. 518-528. Date of Electronic Publication: 2024 Apr 08.Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9100935 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Mechanism of NLRP3 Inflammasome in Epilepsy and Related Therapeutic Agents.

  • Authors : Chen J; Department of Pharmacology, Ningxia Medical University, Yinchuan 750004, China.; Gao Y

Subjects: NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/antagonists & inhibitors ; Epilepsy*/Epilepsy*/Epilepsy*/drug therapy

  • Source: Neuroscience [Neuroscience] 2024 May 14; Vol. 546, pp. 157-177. Date of Electronic Publication: 2024 Apr 03.Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

DT-13 attenuates inflammation by inhibiting NLRP3-inflammasome related genes in RAW264.7 macrophages.

  • Authors : Raina S; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Diagnostic Laboratory Medicine, Clinical Chemistry and Pathobiochemistry, Augustenburger Platz 1, D-13353, Berlin, Germany.; Hübner E

Subjects: Inflammasomes*/Inflammasomes*/Inflammasomes*/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 May 14; Vol. 708, pp. 149763. Date of Electronic Publication: 2024 Mar 13.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel Isoalantolactone-Based Derivatives as Potent NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.

  • Authors : Zhao M; Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, Chengdu 610041, China.; Ye N

Subjects: NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/antagonists & inhibitors ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; Inflammasomes*/Inflammasomes*/Inflammasomes*/metabolism

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 May 09; Vol. 67 (9), pp. 7516-7538. Date of Electronic Publication: 2024 Apr 30.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Monocyte-Derived Macrophages Aggravate Cardiac Dysfunction After Ischemic Stroke in Mice.

  • Authors : Lin HB; Department of Anesthesiology, Zhujiang Hospital Southern Medical University Guangzhou Guangdong China.; Hong P

Subjects: Macrophages*/Macrophages*/Macrophages*/metabolism ; Disease Models, Animal* ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism

  • Source: Journal of the American Heart Association [J Am Heart Assoc] 2024 May 07; Vol. 13 (9), pp. e034731. Date of Electronic Publication: 2024 May 03.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  11,700 results for ""NLR Family, Pyrin Domain-Containing 3 Protein""